COVID-19: ICU costs in Canada

A Canadian Institute for Health Information (CIHI) report shows that COVID-19 patients remain in hospital for about 15 days and the average cost per COVID-19 patient in the ICU is more than $50,000 ( cihi.ca/en/covid-19-ho… ). 🧵1/
The average cost for treating a patient with COVID-19 is more than $23,000 which is 4x higher than a patient with influenza. For those that are still uncertain, even financial data can tell you and come to the conclusion that COVID-19 is significantly worse than the flu. 2/
Unfortunately 1 in 5 COVID-19 patients admitted to the ICU dies there. CIHI estimated the hospitalization cost of COVID-19 in Canada (excluding Quebec) was nearly $1 billion from January 2020 to March 2021 and the cost tripled between November 2020 and March 2021. 3/
The report provided the average estimated cost of a hospital stay for several conditions:
- $27,093 = Kidney transplant
- $23,111 = COVID-19
- $8,433 = Pneumonia
- $7,446 = Heart attack
- $6,349 = Average hospital stay (non-COVID)
- $4,959 = Influenza

4/
Looking specifically at the ICU, COVID-19 patients stay for 21 days on average and are much sicker than most other patients. "The one major distinction about COVID patients in the ICU is they stay a long time. 5/
They take a long time to recover, if they recover at all," says Dr. Donald Redelmeier, a professor at the University of Toronto's faculty of medicine ( cbc.ca/news/health/ci… ). 6/
Since Dec. 14, 2020 (when COVID-19 vaccines began in Ontario) until Sept. 4, 2021 there have only been 25 fully vaccinated individuals in the ICU and only 1 under the age of 50 ( ). 7/
Just in the last 2 months there have been nearly 300 ICU admissions and 0 fully vaccinated deaths under the age of 50. Ontario has released data showing the impact of vaccines ( publichealthontario.ca/-/media/docume… ). 8/
In the past 30 days, unvaccinated individuals were 7.9 times more likely to become infected than fully vaccinated individuals. 9/
In the past 30 days, unvaccinated adults 60 years of age or older were approximately 30.3 times more likely to be hospitalized due to COVID-19 compared to those fully vaccinated. You can see the difference in hospitalization rates in the graph. 10/
Alberta is now requesting potential help from Ontario and Quebec to take ICU patients in their crumbling healthcare system due to COVID-19 hospitalizations amongst mostly unvaccinated individuals ( cbc.ca/news/canada/ed… ). 11/
Alberta health care workers are now being briefed on the critical care triage protocol which describes how to cope if intensive care units no longer have the resources to care for every critically ill patient ( cbc.ca/news/canada/ed… ). 12/
The protocol has never been enacted but with 20 new COVID patients admitted to the ICU every day, they are getting ready to use it. "I can not stress enough how serious the situation is in our hospitals" said Dr. Verna Yiu, president and CEO of Alberta Health Services. 13/
With the majority of hospitalized COVID patients being unvaccinated, you can start to understand why provinces are implementing vaccine passports to help protect hospitals from becoming overwhelmed which they already are in some places in Canada. 14/
The main goal is to increase vaccine uptake, so that even if breakthrough infections can happen, the people will unlikely be hospitalized. 15/
Another significant objective is preventing unvaccinated people from entering potential super-spreading environments such as high-risk indoor locations ( cbc.ca/news/health/va… ). 16/
This Alberta nurse gives you an idea of what it is like there right now: globalnews.ca/video/rd/5c412… 17/

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More from @jeffgilchrist

20 Sep
COVID-19: Ontario vaccine passports

Ontario's vaccine passport is coming into effect in two days on September 22nd and more details have now emerged how this will be implemented ( news.ontario.ca/en/release/100… ). 🧵1/
The proof does not apply to "Workers, contractors, repair workers, delivery workers, students, volunteers, inspectors or others who are entering the business or organization for work purposes and not as patrons." ( health.gov.on.ca/en/pro/program… ). 2/
Unvaccinated workers are 6.7x more likely to become infected and can still spread the virus to others at these locations. Over the last week, vaccines are still 85.2% effective at reducing infections ( gilchrist.ca/jeff/COVID-19/… ). 3/
Read 16 tweets
18 Sep
COVID-19: MMR and Tdap vaccines may reduce severity of COVID-19

For some time now scientists hypothesized that immune memory for other viruses could potentially reduce severity of COVID-19 as well. 🧵1/
Analysis of a large and well-characterized COVID-19 patient cohort revealed that prior MMR (measles-mumps-rubella) and Tdap (tetanus-diphtheria-pertussis) vaccination associates with reduced disease severity and death ( cell.com/med/fulltext/S… ). 2/
How is that possible? A diverse immune T cell response controls viral infections and a major goal of vaccines is to induce a strong and durable T cell memory. Reactivation of memory T cells generated against a different pathogen could enhance immunity to novel pathogens. 3/
Read 11 tweets
17 Sep
COVID-19: UK vaccine updates: Boosters for 50+

JCVI is now recommending booster shots (3rd dose) be offered to those more at risk of serious disease for the following groups no earlier than 6 months after getting the second dose ( gov.uk/government/new… ). 🧵1/
- those living in residential care homes for older adults
- all adults aged 50 years or over
- frontline health and social care workers
- all those aged 16 to 49 years with underlying health conditions that put them at higher risk of severe COVID-19, and adult carers

2/
- adult household contacts of immunosuppressed individuals

3/
Read 16 tweets
17 Sep
COVID-19: UK vaccine update: Children 12-15

Chief Medical Officers from the UK have recommended COVID-19 vaccines for all those 12-15 ( gov.uk/government/pub… ). This would be 1 dose with a second dose determined later (spring) based on more data accrued internationally. 🧵1/4
The recent advice from the UK's Joint Committee on Vaccination and Immunisation (JCVI) did not take into account any benefits to the community or society despite finding marginally better benefits from vaccinating children 12-15. 2/4
In this case the four CMOs looked at a much wider perspective and when taking into account other details including disruption to education, protection of parents and family members, they came to the conclusion that all 12-15 should be vaccinated. 3/4
Read 4 tweets
16 Sep
COVID-19: Pfizer vs Moderna dosing and combo Flu-COVID-RSV

Have you ever noticed that Pfizer's COVID-19 vaccine uses 30 ug doses and Moderna is100 ug doses and wondered why (  )? 🧵1/
In real-world effectiveness studies, the Moderna vaccine seems to outperform Pfizer with higher protection.  Since the two vaccines are using the same COVID-19 spike protein design, the two major differences between the vaccines are the dose amount and the time between doses.  2/
Some scientists believe the improved performance is because Moderna's dose is more than 3x higher than Pfizer.  Studies have shown increased neutralizing antibody level production with higher doses of mRNA vaccine given to rats ( science.org/doi/10.1126/sc… ).  3/
Read 10 tweets
8 Sep
COVID-19: UK decision not to universally vaccinate children 12-15

The UK's Joint Committee on Vaccination Immunisation (JCVI) recently announced they did not support universal vaccination of 12-15 year olds at this time ( gov.uk/government/new… ). 🧵1/
How did they come to a different conclusion than all the other countries who are already offering vaccines to those 12+ despite actually admitting that the benefits from the vaccine for 12-15 are "marginally greater than the potential known harms"? 2/
As usual, you need to look at the fine print and context they were using. First, they seemed to be using ICU treatment as their baseline and noted that only 2 healthy children per million need ICU care which was too small of a benefit ( washingtontimes.com/news/2021/sep/… ). 3/
Read 34 tweets

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