The mechanism of action may be more than just 5HT based. Sigma 1 receptor (S1R) plays a role. Methylated serotonin mimetics like DMT, Psilocin, or psilocybin are known to hit the same receptors.
Keep in mind, stress and depression raises cortisol levels and weakens the immune system. Elimination of this may eliminate the Nocebo effect in many C19 trials.
No other drug trials have a captive population doom scrolling bad news about COVID. Placebo/Nocebo confounders.
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1.5yr ago I posted a video reminding folks that even if this virus is man made, nothing is new under the sun and the parts all have ancestors. Our immune systems have some memory of the ancestors.
Most colleagues were so engrossed in fear that they argued against this , eventually blocked me, only to occasionally return and scream 650K deaths & blood on my hands for being lax.
While excess mortality and comorbidity data implies the lockdowns likely did more harm.
Meanwhile over $7T has been printed and given to friends of government.
Supply shortages rage on throughout the Diagnostics space.
Economy has been wrecked. Kids education sacrificed.
If you can print money for emergencies, people manufacture emergencies to print money.