"Two new caches of documents have added considerable substance..to the idea that the SARS2 epidemic may have originated in a lab accident."

Nicolas Wade: New Routes to Making Covid-19 in the Lab
link.medium.com/O1xv2MomNjb
"One is a grant proposal written by EcoHealth in March 2018 to DARPA, a research agency in the Department of Defense."
"A prominent feature of the proposal is to 'introduce..human-specific cleavage sites' into SARS-like viruses. Such a procedure is eye-catching, if not jaw-dropping, because the distinctive feature of the SARS2 virus is a genetic element known as a furin cleavage site.
"The element greatly enhances the virus’s ability to infect human cells. The furin cleavage site attracted attention from the start because SARS2 is the only member of its family — a group known as Sarbecoviruses — to possess one."
"This led to the suggestion that the furin cleavage site had been genetically engineered into..a SARS-like virus, creating SARS2."

"The..grant proposal..now puts beyond doubt that engineering cleavage sites into SARS-like viruses was a technique to be explored at..Wuhan"
"A second remarkable document..was..grant proposal and progress reports submitted by EcoHealth to..National Institute of Allergy and Infectious Diseases..in support of..research at..Wuhan..2014 to 2019. It was obtained by the Intercept after..FOIA request, followed by.a lawsuit."
"[I]t’s now clear..the Wuhan researchers were..creating..novel viruses, which they..tested on humanized mice..The novel viruses caused the mice to lose more weight than the parent virus.., and generated far more viral particles..The..enhancements represent a gain of function."
"In a letter of July 7, 2016 [from the NIH]..Ecohealth Alliance..was told that its experiments at the Wuhan institute must stop immediately if any novel virus started growing 10 times faster than its parent virus."
"In fact the novel viruses attained growth rates up to 10,000 times faster than that of their parent virus, the new documents show. But there’s no evidence that the Wuhan researchers stopped the experiments."
"The traffic stop turned flashing red and they just drove straight through it. All that..[NIAID Director] Fauci and..[NIH Director] Collins did was award them another grant."

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More from @R_H_Ebright

23 Sep
"A GRANT PROPOSAL written by the US-based nonprofit the EcoHealth Alliance and submitted in 2018 to..DARPA, provides evidence that the group was working — or at least planning to work — on several risky areas of research."
theintercept.com/2021/09/23/cor…
"Among the scientific tasks the group described in its proposal..was the creation of full-length infectious clones of bat SARS-related coronaviruses and the insertion of a tiny part of the virus known as a “proteolytic cleavage site” into bat coronaviruses."
"Of particular interest was a type of cleavage site able to interact with furin, an enzyme expressed in human cells."
Read 9 tweets
21 Sep
"Wuhan scientists were planning to release enhanced airborne coronaviruses into Chinese bat populations to inoculate them against diseases that could jump to humans, leaked grant proposals dating from 2018 show."

telegraph.co.uk/news/2021/09/2…
"They also planned to create chimeric viruses, genetically enhanced to infect humans more easily, and requested $14million from the [US] Defense Advanced Research Projects Agency (Darpa) to fund the work."
"The bid was submitted by British zoologist Peter Daszak of EcoHealth Alliance, the US-based organisation, which has worked closely with the Wuhan Institute of Virology (WIV) researching bat coronaviruses. Team members included..Shi Zhengli, the WIV researcher dubbed 'bat woman'"
Read 7 tweets
21 Sep
EcoHealth: "We will analyze..SARSr-CoV..sequences for..proteolytic cleavage sites in S2 and..potential Furin cleavage sites..[W]e will introduce..human-specific cleavage sites and evaluate growth..in Vero cells and HAE cultures."

(full proposal now up)
drasticresearch.files.wordpress.com/2021/09/main-d…
Read 4 tweets
20 Sep
EcoHealth: "We will analyze all SARSr-CoV..sequences for..proteolytic cleavage sites in S2 and for..potential Furin cleavage sites..[W]e will introduce appropriate human-specific cleavage sites and evaluate growth potential in Vero cells and HAE cultures."
drasticresearch.files.wordpress.com/2021/09/defuse…
DARPA:

"1. The proposal is considered to potentially involve GoF/DURC research because they propose to synthesize spike glycoproteins which bind to human cell receptors and insert them into SARSr-CoV backbones to assess whether they can cause SARS-like disease.
"2. However the proposal does not mention or assess potential risks of Gain of Function (GoF) research.

"3. Nor does the proposal mention or assess Dual Use Research of Concern (DURC) issues, and thus fails to present a DURC risk mitigation plan.

(drasticresearch.files.wordpress.com/2021/09/defuse…)
Read 6 tweets
17 Sep
"More than a hundred safety breaches have been investigated at UK laboratories that handle dangerous viruses and other pathogens in the past 15 years, records obtained by The Times show."

Safety breaches at UK labs that deal with deadly viruses
thetimes.co.uk/article/safety…
"The real number of accidents and near-misses will have been [much, much] higher, as the executive has refused to provide any information of incidents involving so-called 'schedule 5' substances, which include diseases such as ebola and anthrax."
The sham list omits even widely reported lab incidents, such as the Foot and Mouth Disease virus leak from BSL-4 lab at Pirbright in 2007--which required culling 4 M animals and cost 3 B GBP--and the isolation-suit failures in Ministry of Defence BSL-4 lab at Porton Down in 2013.
Read 9 tweets
12 Sep
Virus research: Germany and the EU are also working together with bio-laboratories in Wuhan

Virusforschung: Auch Deutschland und die EU arbeiten mit Bio-Laboren in Wuhan zusammen
de.rt.com/meinung/122326…
<< EU maintains two virus archives in one of the bio-laboratories in Wuhan. The project is funded by the EU investment program "Horizon 2020". A German-Chinese high-security laboratory also works in the city. But the international public hardly knows anything about it. >>
<< The European Union played a major role in promoting the WIV..The European Union set up, promoted, and financed a 'European Virus Archive' and a 'Global Virus Archive' in the WIV. >>
Read 5 tweets

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