1. The preprint from the @NIH mix-&-match #Covid vaccine trial is out. Interesting though not surprising findings. It is too bad the study was conducted using a full dose of Moderna's vaccine, given the fact the company's booster is a half dose. medrxiv.org/content/10.110…
2. The fact that the study used 2x as much vaccine in the Moderna arm than Moderna is proposing to give people with its booster shot means the Moderna findings have to be taken with a big grain of salt. It's a huge shame.
3. The study found all boosters did what the name implied — they boosted antibody levels. But mRNA boosters did it more than the J&J vaccine did.
Caveat: These findings are based on antibodies in blood not vaccine effectiveness trials. Don't know how long the boost will last.
Caveat: These findings are based on antibodies in blood not vaccine effectiveness trials. Don't know how long the boost will last.
4. The list of limitations on the mix-&-match study are sobering. These data point in a direction. But to paraphrase @matthewherper, they aren't a lot to make policy on. 
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