Systemic physiological harm can be mapped to aging. This study shows evidence goes far beyond a general mapping to molecular markers:

Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 Survivors

Figures explained in thread
1/
ncbi.nlm.nih.gov/pmc/articles/P…
Black dashed line in the figure shows the direct correlation of chronological age (horizontal axis) with genetic age markers (vertical axis) for uninfected individuals (blue), and significant departure for infected individuals (red) especially for younger individuals.

2/
This figure shows the same results but after subtracting the chronological age. The age difference that results across the population is

10.45 ± 7.29 years (+5.25 years above the range of normality) compared with 3.68 ± 8.17 years for COVID-19-free population (p < 0.0001)

3/
Here are the results separated into three age groups, with younger people (under 60) aging by 15 years, 61-69 aging by 10 years, and 70 and over gaining about 3 years on average.

The linear fit of aging extrapolates to a biological aging of over 30 years for children.

4/
COVID infection aging for

20 year olds is 27 years, so they have a biological marker age almost 50

30 year olds is 23 years, so a biological marker age of 53.

40 year olds is 18 years, so biological marker age is 58

Children 5 years old, gain 33 years, to be almost 40.

5/

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More from @yaneerbaryam

18 Oct
Important example of the failure of current school guidelines. Wishful thinking doesn't work in a pandemic. This is not just in Ireland.

Covid-19: Primary school closes until November after outbreak of 30 cases

1/
irishtimes.com/news/education… via @IrishTimes
"A primary school in Co Wexford has blamed “serious flaws” with revised close contact rules for an outbreak of more than 30 cases of Covid-19, which has forced it to shut until next month.

2/
"It follows an emergency meeting of CBS primary school’s board of management on Sunday evening. The board said it was closing the 270-pupil school as a “vital health and safety precaution for all”.

3/
Read 15 tweets
15 Oct
"Back from the brink: how Japan became a surprise Covid success

7-day average is 700 cases per day, 1/33 peak at end of August. Vaccination, masking, end of summer socializing appear to help.

1/

theguardian.com/world/2021/oct…
Paraphrasing: Previous prime minister, Yoshihide Suga, who ignored his chief health adviser in pushing ahead with the Games, was forced to step down amid stubbornly low approval ratings. He was criticised for emphasising the economy over the virus response.

2/
Recent polls show public expects new prime minister Fumio Kishida to prioritise public health
“The end of emergency doesn’t mean we are 100% free. The government should send a clear message to the people that we can only relax gradually”chief medical adviser Shigeru Omi cautioned
Read 4 tweets
12 Oct
India continues to improve, under 20 cases per day in

11 States: Bihar, Chhattisgarh, Gujarat, Haryana, Jharkhand, Madhya Pradesh, Nagaland, Rajasthan, Sikkim, Tripura, Uttar Pradesh, Uttarakhand.

Population over 600 million.

1/

endcoronavirus.org/india-states-ut ImageImage
Bihar population 100 M, Uttar Pradesh population about 220 M.

Also under 20 cases per day in 5 Union territories:
Andaman & Nicobar Islands; Chandigarh; Dadra, Nagar Haveli, Daman & Diu; Ladakh; Lakshadweep.

2/
Delhi recently, population 31 million, has about 1 case per million

Maharashtra, population 110 million, after opening too early, recently adopted best practices from other states and is now declining down to 2,600 per day, under 25 per million.

3/ ImageImage
Read 7 tweets
12 Oct
Update: The UK House of Commons

Health and Social Care, and Science and Technology Committees

Coronavirus: lessons learned to date

Report released today.

Report quotes:

1/
“Covid-19 has been the biggest crisis our country has faced in generations, and the greatest peacetime challenge in a century. It has disrupted our lives to an extent few predicted; separated friends and families; closed businesses and damaged livelihoods; ..

2/
“…and, most tragically of all, it has been associated with the deaths of over 150,000 people in the UK and nearly 5 million people worldwide to date.

3/
Read 12 tweets
7 Oct
India: Assam, a state of 30M people, has 314 cases per day, 1 per 100,000 population.

Current Covid-19 advisory designates any area with more than 10 cases in the last 7 days as a "total containment zone."

1/
covid19.assam.gov.in/covid_asm_advi…
In a total containment zone, unauthorized entry or exit is prohibited.

Essential services operate within limited hours. Government, offices, education, and business establishments are closed, with few exemptions.

2/

covid19.assam.gov.in/containment-zo…
In addition, there are state wide restrictions including suspension of all inter-district travel services, a mask mandate, limited gathering sizes, even outside of total containment zones.

3/
Read 8 tweets
5 Oct
COVID-19 must be eliminated, not become endemic, if America is to survive

"More and more people seem to be accepting the idea the future will include COVID-19.

"Those people don’t understand what that means.

1/

dailykos.com/story/2021/10/…
Take The Wall Street Journal, which on Friday published an article stating “COVID-19 will soon become endemic—and the sooner the better.”
"This... is not just a formula for millions of deaths, but an absolute ticket to the end of the line for America, and likely for what..

2/
"we currently think of as modern society. We simply cannot live with endemic COVID-19.

"Hang on, let me say that again: We. Cannot. Live. With. Endemic. COVID-19. I can be louder. And I will be.

3/
Read 34 tweets

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