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Eric Feigl-Ding Profile picture
@DrEricDing
Oct 22, 2021 • 14 tweets • 6 min read • Read on X
BEST BOOSTER? Mix it up — but depends which you had first. Switching vaccine for the booster seems to be the best—Pfizer to Moderna booster, Moderna to Pfizer for booster, and J&J should switch to Moderna / Pfizer booster. HT to @ScientistSwanda. #COVID19 #BoosterShots #vaccinate Image
2) Vaccine efficacy and booster eligibility summarized here by @MedicalLetter. secure.medicalletter.org/downloads/1621… Image
4) Here are the official eligibility criteria for boosters. Note that Moderna as a booster is a modified 50 mcg. Normal first 2 shots of Moderna is 100 mcg.
5) that said, if you have a cancer or immunocompromised like #MultipleMyeloma, then you should go with the Moderna full dose 100 mcg two shots. Ask your doctor if still possible.
6) Moderna 2 shots (2x 100 mcg) yielded 6x greater antibody response than 2 shots of Pfizer. Might be too late to change; but just FYI for those not vaccinated yet.
7) This booster study (top post) is funded by the NIH. Though keep in mind the Moderna “booster” they tested was the 100 mcg full dose, and not the 50 mcg currently FDA authorized Moderna booster. So while Moderna looks strongest, keep in mind it’s 2x the current booster dose. Image
8) The study hold a wealth of data on boosters. Really key is that J&J seems to lag all the other boosters in terms of antibody response. medrxiv.org/content/10.110…
9) What does booster offer) more than 90% risk reduction in SEVERE DISEASE in Israel 🇮🇱 for those who got 3 Pfizer doses versus 2 doses after 6 months!!! And it benefits both elderly and younger adults!!! Middle age should definitely take booster! Image
10) This is what happens when nationwide boosters were rolled out in Israel 🇮🇱. Its Delta variant wave stopped soon after. Image
11) good morning - 100 million at risk Americans can likely get boosters starting today.
12) Forgot to mention - it seems having initial Pfizer doses then switching to Moderna has slightly less severe headache, fatigue, nausea, and myalgia than a 3rd Pfizer dose.
medrxiv.org/content/10.110… Image
13) Unpopular thing to utter aloud — but many scientists think 1 dose J&J is way too weak. It should never have been a one dose vaccine in the first place. 2 dose should have been minimum.
14) Even 2 doses of J&J is much weaker for T cell stimulation versus 2 Pfizers.
15) What is better than figuring out which booster to get? GOING OUT TO GET ONE! see thread 🧵 of evidence 👇

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More from @DrEricDing

Eric Feigl-Ding Profile picture
Mar 14
I’ve said it before, and I’ll say it again… once upon a time, liberals did have our own “Leftist Joe Rogan”… his name was Joe Rogan…

Here he is advocating for socialized medicine, healthcare for all, and supporting labor unions to protect workers.
2) Recall, Rogan was once pro Obama and pro Bernie Sanders, and pro Yang Gang, and anti Trump. It’s sad he has since failed to the dark side. But like Vader… maybe he can be redeemed someday and come back to the light.
3) *Fallen, not failed (above).

Joe Rogan was also pro gay rights and pro DACA and pro helping inner city communities that suffer economic and social injustices. It’s sad what he has become. I feel we should try to pull & welcome him back someday. Everyone can be redeemed.
Read 4 tweets
Eric Feigl-Ding Profile picture
Feb 26
BREAKING—FDA suddenly cancels meeting to update next season’s flu vaccines, with zero explanations. Any delays will jeopardize next year’s vaccine supply chain. Image
2) Folks who follow me know that I’m no bullshitter. I criticized past pandemic response right and left, and have called balls and strikes without bias. And I often say things that doctors & epidemiologists are whispering among themselves but don’t say publicly. (Cough cough) ⬇️
3) While I don’t recommend hoarding… I think stocking up on flu antivirals, which you can obtain prophylactically (preventively) from doctors if you ask nicely why you’re high risk, can be a good idea. I know many doctors, epidemiologists and virologists who do for their family.
Read 6 tweets
Eric Feigl-Ding Profile picture
Feb 26
Doctors are debunking RFK Jr’s claim that 20 hospitalized measles cases in Texas are there for mainly quarantine. Doctors on the ground say the 20 kids hospitalized are having trouble breathing. Oh and they are all unvaccinated against measles, which RFK Jr neglects to mention. Image
2) RFK Jr told Trump today there’s now 2 measles deaths.
3) RFK Jr is a tear with his FDA today. A dark Darwinian future lies ahead for America.
Read 4 tweets
Eric Feigl-Ding Profile picture
Feb 26
BREAKING—Reports coming in about potentially *2 measles deaths* in Texas, not just one, according to an HHS briefing to the White House today.
2) Earlier today, one measles death in an unvaccinated child was reported in Texas. Image
3) It seems to be RFK Jr who said it in an official Trump WH cabinet meeting today. Not saying he doesn’t lie, but he is now HHS Secretary
Read 6 tweets
Eric Feigl-Ding Profile picture
Feb 21
Woke or biology? There are actually more than the basic “male” XY & “female” XX sexes. Why? Because biology also creates people with single X chromosomes, or extra chromosomes like XXX, XXY, XYY, or XXX+, plus many 🧬genes. 👉All I’m asking is— please be kind to others. Thanks🙏 Image
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2) “The most frequent SCAs include Turner syndrome (45,X), Klinefelter syndrome (47,XXY), Trisomy X syndrome (47,XXX), and Double Y syndrome (47,XYY).”

pmc.ncbi.nlm.nih.gov/articles/PMC10…
3) “The phenotype seen in SCAs is highly variable and may not merely be due to the direct genomic imbalance from altered sex chromosome gene dosage but also due to additive alterations in gene networks and regulatory pathways across the genome as well as individual genetic modifiers.”
Read 5 tweets
Eric Feigl-Ding Profile picture
Feb 16
I'm shocked a lot of doctors don't know about this newer flu antiviral drug called Baloxavir (XOFLUZA)... that shortens your flu illness by 33%, and reduces your viral load by day 2, versus what a placebo takes 5-6 days to achieve. Baloxavir also seems superior to TAMIFLU (oseltamivir) for smashing your viral load on 2 day, achieving what takes Tamiflu 3-4 days. CDC even lists Baloxavir on their website as one of the top 4 drugs that it tracks whether it works against new flu strains (it works)Image
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2) "Baloxavir was associated with significantly more rapid declines in infectious viral load than placebo or oseltamivir (Figure 3A and 3B)."
nejm.org/doi/full/10.10…
3) Adverse events for baloxavir were no different than placebo. in fact theres even hints that it could be lower than Tamiflu.

"Adverse events that were considered to be related to the trial regimen were more common in oseltamivir recipients (8.4%) than in baloxavir recipients (4.4%, P=0.009)"Image
Read 13 tweets

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