Local public health chiefs in England are breaking from the government’s official guidance and recommending protective measures to combat a surge in coronavirus cases.
Study points to possible Covid brain damage mechanism:
Covid protein (protease) cuts a protein (NEMO) important in cells forming the walls of small capilaries of the brain (endothelial cells). This results in cell death and loss of capilaries.
"We obtained evidence that brain endothelial cells are infected and that the main protease of SARS-CoV-2 (Mpro) cleaves NEMO, the essential modulator of nuclear factor-κB.
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Loss of cells lining the walls of capillaries in the brain makes them unable to cary blood—harming the brain. What is left are called "string vessels" and are found in increased numbers in Alzheimer's and Parkinson's
"Brazilian senators have recommended President Jair Bolsonaro be charged with 10 crimes, including crimes against humanity, alleging his "reckless" mismanagement of the Covid-19 crisis that led to the deaths of hundreds of thousands of people.
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"Lawmakers investigating the President officially presented their report on Wednesday, condemning the populist leader's handling of the crisis and pushing for him to face a swathe of charges.
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"A primary school in Co Wexford has blamed “serious flaws” with revised close contact rules for an outbreak of more than 30 cases of Covid-19, which has forced it to shut until next month.
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"It follows an emergency meeting of CBS primary school’s board of management on Sunday evening. The board said it was closing the 270-pupil school as a “vital health and safety precaution for all”.
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Black dashed line in the figure shows the direct correlation of chronological age (horizontal axis) with genetic age markers (vertical axis) for uninfected individuals (blue), and significant departure for infected individuals (red) especially for younger individuals.
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This figure shows the same results but after subtracting the chronological age. The age difference that results across the population is
10.45 ± 7.29 years (+5.25 years above the range of normality) compared with 3.68 ± 8.17 years for COVID-19-free population (p < 0.0001)
Paraphrasing: Previous prime minister, Yoshihide Suga, who ignored his chief health adviser in pushing ahead with the Games, was forced to step down amid stubbornly low approval ratings. He was criticised for emphasising the economy over the virus response.
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Recent polls show public expects new prime minister Fumio Kishida to prioritise public health
“The end of emergency doesn’t mean we are 100% free. The government should send a clear message to the people that we can only relax gradually”chief medical adviser Shigeru Omi cautioned
Bihar population 100 M, Uttar Pradesh population about 220 M.
Also under 20 cases per day in 5 Union territories:
Andaman & Nicobar Islands; Chandigarh; Dadra, Nagar Haveli, Daman & Diu; Ladakh; Lakshadweep.
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Delhi recently, population 31 million, has about 1 case per million
Maharashtra, population 110 million, after opening too early, recently adopted best practices from other states and is now declining down to 2,600 per day, under 25 per million.