1. Ariadne's Thread - SARS Vaccines

Collection of SARS Vaccine papers for Maze addicts

How was the Minotaur born?
2. Immunogenicity difference between the SARS coronavirus and the bat SARS-like coronavirus spike (S) proteins
Peng Zhou,Zhenggang Han,Lin-Fa Wang, Zhengli Shi

ncbi.nlm.nih.gov/labs/pmc/artic…
3. Immunogenicity of the spike glycoprotein of Bat SARS-like coronavirus

Yu-xuan Hou,Cheng Peng, Zheng-gang Han, Peng Zhou, Ji-guo Chen, Zheng-li Shi

1https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7090579/
4. Following the thread
5. Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity

ncbi.nlm.nih.gov/labs/pmc/artic…
6. Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection

ncbi.nlm.nih.gov/labs/pmc/artic…
7. A 219-mer CHO-Expressing Receptor-Binding Domain of SARS-CoV S Protein Induces Potent Immune Responses and Protective Immunity

ncbi.nlm.nih.gov/labs/pmc/artic…
8. Unravelling the Thread
9. Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells

ncbi.nlm.nih.gov/labs/pmc/artic…
10. Vaccine Design for Severe Acute Respiratory Syndrome Coronavirus

liebertpub.com/doi/10.1089/vi…
11. Recombinant Modified Vaccinia Virus Ankara Expressing the Spike Glycoprotein of Severe Acute Respiratory Syndrome Coronavirus Induces Protective Neutralizing Antibodies Primarily Targeting the Receptor Binding Region

ncbi.nlm.nih.gov/labs/pmc/artic…
12. Recombinant Modified Vaccinia Virus Ankara Expressing the Spike Glycoprotein of Severe Acute Respiratory Syndrome Coronavirus Induces Protective Neutralizing Antibodies Primarily Targeting the Receptor Binding Region

ncbi.nlm.nih.gov/labs/pmc/artic…
13. Minotaur emerges
14. Intranasal Vaccination of Recombinant Adeno-Associated Virus Encoding Receptor-Binding Domain of SARS-CoV Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-Term Protection against SARS-CoV Infection

ncbi.nlm.nih.gov/labs/pmc/artic…
15. Effect of mucosal and systemic immunization with virus-like particles of severe acute respiratory syndrome coronavirus in mice (WIV, 2010)

ncbi.nlm.nih.gov/labs/pmc/artic…
16. Easy for a Mouse
17. A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

ncbi.nlm.nih.gov/labs/pmc/artic…
For whom does the Bell Toll?

Effects of Toll-Like Receptor Stimulation on Eosinophilic Infiltration in Lungs of BALB/c Mice Immunized with UV-Inactivated Severe Acute Respiratory Syndrome-Related Coronavirus Vaccine

ncbi.nlm.nih.gov/labs/pmc/artic…
19. For Ferrets and Monkeys!

Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

ncbi.nlm.nih.gov/labs/pmc/artic…
20. SARS-CoV Spike Proteins Expressed by the Vaccinia Virus Tiantan Strain: Secreted SQ Protein Induces Robust Neutralization Antibody in Mice

liebertpub.com/doi/10.1089/vi…
21. Chimeric Minotaur
22. Chimeric severe acute respiratory syndrome coronavirus (SARS-CoV) S glycoprotein and influenza matrix 1 efficiently form virus-like particles (VLPs) that protect mice against challenge with SARS-CoV

ncbi.nlm.nih.gov/labs/pmc/artic…
23. Development of subunit vaccines against severe acute respiratory syndrome
Du, L., He, Y., Jiang, S., Zheng, B.-J.

journals.prous.com/journals/servl…
24. The Shadow
25. Potent neutralization antibody elicited in mice by SARS-associated coronavirus spike protein S1 domain

pubmed.ncbi.nlm.nih.gov/15640862/
27. The expression and antigenicity of a truncated spike-nucleocapsid fusion protein of severe acute respiratory syndrome-associated coronavirus

ncbi.nlm.nih.gov/labs/pmc/artic…
28. Truncated Recombinations, a Mouse's Nightmare
29. More
1. Studies of SARS vaccines
hkmj.org/abstracts/v14n…
2. Animal coronavirus vaccines: lessons for SARS
pubmed.ncbi.nlm.nih.gov/15742624/
3. SARS Vaccine Development
ncbi.nlm.nih.gov/labs/pmc/artic…
4.Vaccine Design for SARS
liebertpub.com/doi/10.1089/vi…
5. SARS Vaccination
cmi.ustc.edu.cn/1/3/193.pdf
30. From SARS 1 to SARS 2

A Review on SARS-CoV-2-Induced Neuroinflammation, Neurodevelopmental Complications, and Recent Updates on the Vaccine Development

ncbi.nlm.nih.gov/labs/pmc/artic…
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More from @BillyBostickson

1 Nov
1. Calling for Volunteers to help map BSL 3 & 4 Labs

#DRASTIC Bio-Safety Labs World Map

Only 12 Lab complexes added so far 😧

google.com/maps/d/viewer?…
2. The Volunteer who went AWOL

Unfortunately we lost our volunteer BSL Lab mapmaker to the competition

(they got a 110,00 GBP grant..we didn't)

kcl.ac.uk/news/project-a…
3. Decentralised Cooperation

Due to lack of funds, we want to decentralise the work:

One or more people from every nation to fill in a document with:

Lab names
Latitudes & Longitudes
Description
Size
Photos
Research fields
Viruses studied (if known)
Researchers
Reference URLs Image
Read 9 tweets
1 Nov
1. Latest Updates from @AGHuff on LinkedIn

The Soap Opera gets even more soapy! ImageImageImage
2. Today's Main Statement of Interest
"I GUESS I SOLVED WUHAN FOLKS. ALL BECAUSE I REMEMBER A STUPID QUESTION PETER ASKED ME IN 2016.STUPID BECAUSE HE BROKE HIS SECURITY CLEARANCE OR BECAUSE HE DIDN'T REALIZE WHAT HE TOLD ME IS ABOUT THE MOST SENSITIVE TYPE OF IC SECRET THERE IS" Image
3. "The government is pissed because I won’t tell them first so they can set the narrative. I am sure that they already know as I have told everyone close to me in case they pull some shit"

"Statement to public coming from my attorney shortly" Image
Read 4 tweets
28 Oct
1. North Korean Delegation visiting WIV in 2011

In a forthcoming report!

"Experts of the delegation agreed to establish cooperative relations, and to send visiting scholars to the laboratory learning exchange"
2. Some Names for Researchers to Check
North Korean Academy of Sciences Institute of Microbiology: KIM MUN CHOL
Deputy Director of Pyongyang Medical University Virus Research Institute: RI SUNG IK
Director of North Korean Academy of Sciences Institute of Microbiology: RI IN CHOL
3. KIM MUN CHOL = Kim Myong Chol?

Good Starter

North Korea’s Biological Weapons Program

The Known and Unknown

belfercenter.org/sites/default/…

KIM MUN CHOL = Kim Myong Chol?
Read 8 tweets
28 Oct
@ydeigin Following the unauthorized brandjacking of #DRASTIC by a Russian embezzler (Pharma Bio & Skolkovo) who co-founded youthbiotx.com with CFO Viet Ly (fined $100,000 by SEC for scamming Genprex investors)
dfi.wa.gov/documents/secu…
Comrade Deigin no longer represents #DRASTIC
@ydeigin The original lineage is natural, the new lineage is definitely engineered and likely a bioweapon ;)
@ydeigin What's Yuri's company "Youth Bio" doing in Japan?
Read 13 tweets
28 Oct
"The streets of Zanzibar are empty of prostitutes because the homes are full of them and there is no scandal because there is no shame”

Zanzibar tales told by natives of the east coast of Africa : translated from the original Swahili (1901)

archive.org/details/zanzib…
British Goblins: Welsh Folk-lore, Fairy Mythology, Legends and Traditions (1880)

ia802605.us.archive.org/12/items/briti…

via @PublicDomainRev

publicdomainreview.org/collection/bri…
East of the Sun and West of the Moon, illustrated by Kay Nielsen (1922 edition)

ia802700.us.archive.org/11/items/easto…
Read 6 tweets
27 Oct
1. The Peter Daszak Experience

"I shared a house with Peter Daszak for about 2 and a half years in the early 90's. I had a squat in Cedars Road, Stratford"

linkedin.com/pulse/peter-da…

archive.ph/odnKB
2. Oi Daszak

Whilst jamming with two friends we came up with the bare bones that became 'OI DASZAK' (you stole my poetry).

Based on a true episode as a housemate of Pete's. When recording we tried to put in as much atmosphere and flavour of the era as we could.
3. Oi Daszak - (You Stole My Poetry)

Read 7 tweets

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