Thread by @mahmudme01

The role of COVID vaccine is not just to create immunity, it also causes adverse effects and perhaps makes people vulnerable to COVID during virus favorable weather. Spike protein goes to the cell membrane which can potentially change cell membrane tension.

An altered membrane tension can play a diverse role in cellular processes such as cell-cell, cell-vesicle, and cell-virus fusion. Membrane fusion is a highly regulated process. Therefore, someone can expect very diverse and rare side effects due to vaccination.

Many vaccine side effects are unnoticed because they do not show a pattern statistically. When two interfaces fuse together, based on tension differences fusion outcome can be completely different. This is a fact.

If you let a droplet fuse with a liquid bath, you will see a varied penetration depth of the droplet depending on the tension differences of bath & drop surface. Maximum penetration happens at a critical tension difference. This must be true for virus-cell membrane fusion process

At a critical tension difference, the virus will penetrate cells in the most efficient way. Similarly, during vaccine design, you must need to check if spike protein changes cell membrane properties at all which will definitely play role in adverse effects.

As critical tension difference between fusing membrane determines efficient RNA penetration into the cell, you must need to be careful about the cause which can make that happen. A critical temp, a lower pH, cholesterol, etc can be the likely reason.

However, the dominant role is played by the temperature. This is how seasonality matters. A critical temp (which is lower than the body temp) on the skin or in the nasal airway can play role in favorable virus replication. This critical temp is modulated by air temp & humidity.

Wet-Bulb Temp can correlate with nasal airway & skin temp. If you want to slow down the replication process, you need to stop enhanced penetration of viral RNA into the cell which can be done by raising WBT. >15C WBT happens to be safe where 12C WBT is the most virus fav.

During winter, in many countries especially northern US & Europe, indoor becomes virus fav (around 12C). How do you raise WBT? There could have many ways. The best way could be taking shower with sufficiently hot water, wearing masks with a face shield, doing indoor exercise etc.

Do you want to keep raising WBT all the time? Of course not. You want to avoid efficient penetration of the virus RNA into the cell, but you will also like to keep going for many useful penetrations (such as other important cellular transport processes).