With the banning of trans fats from hydrogenated vegetable oils, did you ever wonder how they continue to make Crisco and other shortenings? I did.
They're made via a process called interesterification, which turns triglycerides solid at room temp.

Interesterified fats may be no more safe than trans fats, and may be responsible for a rise in cardiovascular deaths since 2011.

ncbi.nlm.nih.gov/labs/pmc/artic…
Unfortunately, no one seems to know how much of this stuff is being used, but it appears to be in lots of processed foods, especially baked goods.

They increase blood viscosity leading to increased thrombosis (blood clotting).
More on these fats. This issue is being completely overlooked.

Another reason not to eat ultra-processed foods.
truthinlabeling.org/blog/2019/10/2…
Some more on interesterified fats. Fat spreads, baked goods, and biscuits (cookies) are the largest sources.

Unfortunately, there are no labeling requirements.
Estimated intake of interesterified fats in the U.S. is ~3% of energy, which is high (if you ask me).

Health effects of these fats is not known, but it's worrying that most studies seem focused on whether they raise blood lipid levels, and they're deemed safe if they don't.
We're in the midst of another vast human experiment, where an industrially modified nutrient is put into the food supply in large amounts.

There are good reasons to be wary of them.

onlinelibrary.wiley.com/doi/full/10.11…

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More from @Mangan150

17 Nov
Men have ~5 times the rate of heart attack and heart disease in middle age, compared to women.

Hypothesis is that it's due to rheological properties of blood, and that regular blood donation can fix this. Image
Essentially, women have blood that has a higher proportion of newer RBCs, as do blood donors.

content.iospress.com/articles/clini…
Direct relation between blood viscosity and insulin resistance.

Idea is that high viscosity means blood can't properly perfuse muscle, which is where 80% of glucose goes. pubmed.ncbi.nlm.nih.gov/9535148/
Read 14 tweets
9 Nov
So-called Blue Zones, in addition to being cherry-picked for an agenda, are concentrated in regions with no birth certificates and short lifespans.

In other words, much of what's "known" about Blue Zones could be fraud. Image
"Surveying the ‘blue zone’ of Ikaria, Chrysohoou et al. observed that the oldest-old have... a 10% illiteracy rate, an average 7.4 years of education, and a 99% rate of smoking in men."

IOW not believable as a have for supercentenarians.

biorxiv.org/content/10.110…
*haven
Read 4 tweets
10 Oct
SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: Implications for microclot formation in COVID-19

Fibrin resistant to fibrinolysis (clot dissolving) is a feature of many inflammatory diseases.
medrxiv.org/content/10.110…
Iron is involved in both hypercoagulation and hypofibrinolysis

Free iron does this but level of free iron depends in part on total body iron.

academic.oup.com/ib/article-abs…
Amyloid blood clots, i.e. abnormal clots, are seen in both type 2 diabetes and Covid

link.springer.com/article/10.118…
Read 4 tweets
6 Oct
My article, "Iron: an underrated factor in aging", has been published by the journal Aging.

I hope that this article will bring attention to the role of iron in healthspan and lifespan.

I'm also quite happy they agreed to publish it.
aging-us.com/article/203612
"iron satisfies many of the conditions we might look for in a universally pro-aging substance. It accumulates with age; it is associated with many age-related diseases such as cardiovascular disease, cancer, and Alzheimer’s disease;"
"it catalyzes the formation of cellular junk molecules and helps to prevent their turnover; removal of iron from plasma may be rejuvenating; and people with lower levels of body iron – blood donors – have a lower mortality rate."
Read 5 tweets
5 Sep
Over age 60, half the population has metabolic syndrome, and plenty of younger people have it too. And this was >5 years ago.

Metabolic syndrome is the very definition of leaving yourself open to acute and chronic disease.

Yet health authorities don't talk about this.
People with metabolic syndrome have 7 times the risk of having a Covid diagnosis

pubmed.ncbi.nlm.nih.gov/32924000/
People with metabolic syndrome have 3-6 times the rate of cardiovascular death

pubmed.ncbi.nlm.nih.gov/11315831/
Read 4 tweets
16 Aug
How deadly is Covid?

John Ioannidis of Stanford University estimates 2.4% IFR in community dwelling elderly, age >70

Estimate is 5.5% among elderly overall, which means nursing home residents had much higher death rates

medrxiv.org/content/10.110…
Ioannidis estimates an infection fatality rate of 0.05% among those under 70.

But that's *everyone* under 70, including those with comorbidities.

ncbi.nlm.nih.gov/pmc/articles/P…
We know (according to the CDC) that 95% of those who died from Covid had at least one underlying health condition, such as obesity, hypertension, and diabetes

Read 4 tweets

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