"the approach. will be targeted to a specific pathogen, but It Is applicable to several different pathogens. For example, an approach may be used to develop therapeutics against 20 different pathogens"
3. Professor Ron Taylor
This project started in May 1996 at the University of Virginia. Taylor and his colleagues developed a heteropolymer that functions on the one end to connect to the CR 1 site of the red blood cells, while the other end is tailored to the specific pathogen.
4. Mesenchymal Stem Cells
DARPA also funded research into mesenchymal stem cells (MSCs) modified to have surface receptors designed for specific pathogens. When pathogen is detected, part of cell's DNA Is turned on to produce a gene protein product targeted to kill the pathogen
5. Strategy
To address specific Biological warfare agents, we will fund work at facilities such as USAMRIID, where actual bioagents are. kept. to determine If the therapeutics are effective In animal models.
6. Pharmaceutical Industry
DARPA will provide the thrust & the biotech industry & pharmaceutical industries will take over these products (clinical testing & development) to commercialize them for their own purposes.
DoD will then procure them via "normal" commercial routes
7. Unconventional Pathogen Countermeasures
"The most sinister offensive biological warfare scenario employs surprise, Immediate proximity &
rapidly lethal, persistent agents in overwhelming quantities"
BAA 97-23 Pathogen Countermeasures
Program Manager: CPR Shaun Jones, MD,USN
8. Advanced. Diagnostics
Program Manager: Dr. Stephen Morse
BAA 97-24 Advanced Diagnostics for Pathogens
9. Red Blood Cell Pathogen Decoy & Destruction
University of Virginia
Boston University - Mark Bitensky birensky@enra.bu.etlu
10. Sequential Auto Vaccination by Stem Cells
Daniel R. Marshak
dmarshak@osiristx.com
OSIRIS Therapeutics, Inc. .
Baltimore, MD
You have a radically new idea for fighting pathogens that colleagues are dubious about
Where would you go for funding?
To the NIH?
NIH would ask a committee of peers to evaluate it who can be brutal about radical concepts
12. Scripps - DARPA - Lerner
Richard Lerner, president of The Scripps Research Institute, another DARPA adviser, notes that the agency needs to keep in mind that ''you never know what you want to discover until you discover it."
DARPA was unable to locate any documents concerning "human cellular platforms used for biological warfare therapy," as you requested.
DARPA advises that this division does not exist, nor does DARPA have such a research program
14.Synthetic Polio
DARPA failed to inform anyone that one of its “unconventional” projects was $US300,000 ($393,939) to fund a trio of scientists who thought it would be a neat idea to synthesise polio.
They constructed the virus using its genome sequence, which was available on the Internet, and obtained the genetic material from companies that sell made-to-order DNA.
But building up the long chain of DNA from smaller pieces proved frustratingly difficult. Eventually, Dr. Cello simply ordered most of the completed sequence from a scientific supply house, Integrated DNA Technologies of Coralville, Iowa
DARPA provided $300K over the last 3 years for the work
''Understanding the process of viral DNA production is key to identifying new ways to kill viruses & understand how viruses could change & escape from vaccines"
"During shooting in Thailand, I was shocked by Daszak’s fast & loose with facts, his refusal to acknowledge his conflict of interest,& his denial of his gain-of-function res in collaboration with Wuhan lab"
You guessed right, i hope?
@janeqiuchina
She continued:
"I was equally shocked by Daszak’s constant self-promotion and how effective it was."
@janeqiuchina About the film:
"Blame: Bats, Politics & a Planet Out of Balance"
"Christian Frei seemed entranced by hero worshipping, apparently having lost all sense of objectivity & critical judgment. I felt strongly then, as I do now, that the film was a blatant piece of propaganda"
Bloody Hell, it's worse than even I imagined in my darkest nightmares about #scamdemia.
Time to spend some of this tax money on local electronics, biological, ecological, IT, optical, chemistry, engineering & physics labs run by local amateurs for the benefit of our communities?
Short 🧵on Primer & PCR Test issues (Pangolin Covs)
1. The key issue with pangolins and Pcovs is that:
It was discovered that the standard PCR tests used in 2020, and often still used, failed to actually detect many of the betacoronaviruses generously hosted by the pangolins.
2. Unless
The samples are retested with bespoke primers & more accurate PCR tests available now,
We will not know exactly whIch Pangolin (or bat) coronaviruses were hosted by Pangolins at WIV & elsewhere pre-pandemic.
However, "they" (I will name who they are later) should, and perhaps in the future, may retest the stored samples at WIV, IPB, SCAU AND GIABR, to clarify the question of which coronaviruses were present in their pangolin samples.
2. May have been for research and commercial purposes, but they were caught bang to rights.
"LIU initially stated that he did not know what the materials were and that someone must have put them into his bag"
3. When asked why someone would put them into his bag, LIU stated that he did not know, and that maybe he had accidentally put the materials there. After further questioning, LIU acknowledged that the materials were different strains of the pathogen Fusarium graminearum