⚠️BREAKING—HOTEL CROSS TRANSMISSION OF #B11529—Traveler from South Africa🇿🇦 flew to Hong Kong🇭🇰 with new variant—but wasn’t discovered until 4th day of quarantine on 2nd PCR. Another guest across hallway cross-infected—only positive on 8th day on 4th PCR! Both Pfizer vaccinated🧵
2) the viral load of these two with #B11529 in Hong Kong hotels were VERY high. PCR Ct values of 18 and 19!!! That’s insanely high considering they were negative on recent PCR tests. Damn, looks like vaccine evasion could be real with this variant.
3) and hell yes it’s very airborne. The hotel guests were in different room across the hallway from each other. Environmental samples found the virus in 25 of 87 swab across both rooms.
4) I think border and travel restrictions make sense. Especially since Hong Kong 🇭🇰 only caught the case because of a mandatory hotel quarantine. Which countries in the west still have that??? Almost none.
5) This #B11529 variant is bad bad bad. Scientists worldwide are worried. It has a very bad spike mutation profile and it is spreading fast across South Africa 🇿🇦— see thread 🧵 below 👇
6) 32 mutations in one spike protein is helluva a lot. Its “extremely high”. And it has real concerns because of the bad nature of these mutations too.
7) South Africa 🇿🇦 health leaders are extremely worried about #B11529. We expect the WHO will issue a new Greek name to it soon - likely the #NuVariant.
8) the #B11529 Nu variant seems to have a lot of antibody escape properties— escape in multiple epitope classes of the antibody. This is a really bad thing.
10) cases still low but this surge in #B11529 is no joke. Take it seriously.
11) Let’s finally look at the relative growth plotted by @jburnmurdoch - cases of #B11529 surging much faster than Delta. Caveat is that cases are low. But this would be very worrisome if confirmed in the coming days and weeks. Stay tuned. Stay safe. 🙏
12) 500% more infectious for #B11529 is jaw dropping if it is true. Let’s hope the early data is wrong. We actually REALLY REALLY want this early data to be wrong … because if it’s not wrong… it’s cataclysmic. See new 🧵 below.
14) Israel’s testing has now found 3 cases of #B11529 - the second country outside of Africa to have identified it. This is bad. Israel 🇮🇱 and HK are very strict. I just worry for the non strict quarantine and entry testing countries now.
18) WHO mentioned reinfection risk (ie natural infection not a good idea)— it’s based on lots of research in bad mutations among the 32 mutations that #B11529#OmicronVariant has in its spike protein.
3) “Kennedy is set to announce Thursday the planned changes, which include axing 10,000 full-time employees spread across departments tasked with responding to disease outbreaks, approving new drugs, providing insurance for the poorest Americans and more”.
SICKENING—Trump’s DHS just deported a surgeon from Brown University Medical School—who is here legally on an H1B visa that doesn’t expire until 2027, and has committed no crimes. Trained in the U.S. at Ohio State, University of Washington, and Yale as a **transplant surgeon** (one of the most difficult surgical fields in all of medicine!!!), she is a highly trained doctor on kidney transplants, which cannot be easily replaced. Her phone was seized at the border. A federal judge handed down an injunction against her deportation—but she was already deported on a plane en route to Paris. Brown’s kidney transplant clinic is now strained by her deportation.
2) Full text:
PROVIDENCE — A Rhode Island doctor who had traveled to Lebanon to see her parents was prevented from re-entering the United States at Boston’s Logan International Airport on Thursday evening, her lawyer and a colleague said.
Dr. Rasha Alawieh, 34, who lives in Providence, has been working at Brown Medicine’s Division of Kidney Disease & Hypertension since last July, and she [has] been part of the transplant service at Rhode Island Hospital, according to Dr. George Bayliss, the organ transplant division’s medical director. She has been studying and working in the United States for about six years, he said Friday.
The US consulate in Lebanon had issued her an H-1B visa, which is given to people in specialty occupations requiring expertise. The visa was valid through mid-2027, said Thomas S. Brown, an attorney representing her and Brown Medicine.
Alawieh was detained when she returned to Logan airport, and family members are afraid that she is about to be deported to Lebanon, he said.
“We are at a loss as to why this happened,” Brown said. “I don’t know if it’s a byproduct of the Trump crackdown on immigration. I don’t know if it’s a travel ban or some other issue.”
He said her phone has been seized and he has not been able to contact Alawieh.
Bayliss said a lawyer filed a petition with the US District Court in Massachusetts, and Judge Leo T. Sorokin issued an order saying Alawieh should not be moved outside of Massachusetts without 48 hours notice. But he said that message apparently did not reach immigration officials in time, and a plane carrying Alawieh left for Paris.
“This is outrageous,” Bayliss said in an interview. “This is a person who is legally entitled to be in the U.S., who is stopped from re-entering the country for reasons no one knows. It’s depriving her patients of a good physician.”
A US Customs and Border Patrol spokesperson, Ryan Brissette, was not able to immediately answer questions about Alawieh on Friday evening.
Bayliss said Alawieh graduated from the American University of Beirut medical school and came to the United States for a nephrology fellowship at Ohio State University. She then landed a transplant fellowship at University of Washington and had a residency in the Yale hospital system before starting at Brown Medicine last July, he said.
“She’s really a very humble and able person,” Bayliss said. “She takes care of her patients. She is talented and thoughtful and a great addition to our division.”
Bayliss said Alawieh went to Lebanon to visit parents and planned to be gone for two weeks. He said she texted a colleague at 6:30 p.m. Thursday saying she was back in Boston, but then her family heard from immigration officials.
Dr. Paul Morrissey, surgical director of the organ transplant division at Brown University Health, said Alawieh works on getting people in Rhode Island on the list for a kidney transplants, and that’s a crucial job at a time when there has been a lot of focus on the need for kidneys and their equitable distribution.
He said Alawieh should not have had any problem traveling out of the country with an H-1B visa.
“It’s an unfortunate set of circumstances,” Morrissey said. “It’s putting a strain on our office. Her work has been exceptional.”
3) There is a new Trump ban against many countries, including tourist visa bans against all countries in the red and orange lists. This list is still tentative. And it shouldn’t have affected people with existing visas, such and the Brown kidney transplant surgeon
I’ve said it before, and I’ll say it again… once upon a time, liberals did have our own “Leftist Joe Rogan”… his name was Joe Rogan…
Here he is advocating for socialized medicine, healthcare for all, and supporting labor unions to protect workers.
2) Recall, Rogan was once pro Obama and pro Bernie Sanders, and pro Yang Gang, and anti Trump. It’s sad he has since failed to the dark side. But like Vader… maybe he can be redeemed someday and come back to the light.
Joe Rogan was also pro gay rights and pro DACA and pro helping inner city communities that suffer economic and social injustices. It’s sad what he has become. I feel we should try to pull & welcome him back someday. Everyone can be redeemed.
BREAKING—FDA suddenly cancels meeting to update next season’s flu vaccines, with zero explanations. Any delays will jeopardize next year’s vaccine supply chain.
2) Folks who follow me know that I’m no bullshitter. I criticized past pandemic response right and left, and have called balls and strikes without bias. And I often say things that doctors & epidemiologists are whispering among themselves but don’t say publicly. (Cough cough) ⬇️
3) While I don’t recommend hoarding… I think stocking up on flu antivirals, which you can obtain prophylactically (preventively) from doctors if you ask nicely why you’re high risk, can be a good idea. I know many doctors, epidemiologists and virologists who do for their family.