Concentrations of lead (the metal) in blood are a risk factor for heart disease and death on a par with, or greater than, smoking.

How often do you hear that? If you have CAD, does your doc check your blood lead level, or just prescribe a statin?
"Our findings suggest that, of 2·3 million deaths every year in the USA, about 400,000 are attributable to lead exposure, an estimate that is about ten times larger than the current one."

~18% of all U.S. deaths due to lead exposure. Most are due to CVD.
sciencedirect.com/science/articl…
Men in the top third of bone lead level - which by definition one third of men are - had *8x* the risk of death from heart disease.
pubmed.ncbi.nlm.nih.gov/19738141/
To top it off, EDTA chelation therapy, an intervention that the mainstream writes off as quackery, and which removes heavy metals from the body, works to reduce CV events. sciencedirect.com/science/articl…
The Use of N-Acetylcysteine as a Chelator for Metal Toxicity

"Metals removed in these human studies included mercury, lead, gold, and arsenic."
link.springer.com/chapter/10.100…

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More from @Mangan150

25 Nov
The Clot Thickens - Dr. Malcolm Kendrick, by @RootCauseDoctor

Malcolm Kendrick has destroyed the lipid hypothesis of heart disease and left it dead in the water.
rootcausemd.substack.com/p/the-clot-thi…
I recently finished reading "The Clot Thickens", and am now rereading it a 2nd time.

It's that good.
Interesting thing about Dr. Kendrick's theory that coagulation is directly related to heart disease is that it applies to other chronic diseases also, e.g. cancer. onlinelibrary.wiley.com/doi/full/10.11…
Read 6 tweets
25 Nov
Exercise capacity is a strong, inverse predictor of all-cause death rates. Men in the highest quartile (fourth) of exercise capacity had from 1/4 to 1/3 lower risk of dying during several years follow-up.

Exercise was more important than BMI or blood lipids.
Among men referred for exercise testing, those in the lowest quintile (fifth) of exercise capacity had 4.5 times the risk of dying during 6 years of follow-up.
Read 4 tweets
20 Nov
With the banning of trans fats from hydrogenated vegetable oils, did you ever wonder how they continue to make Crisco and other shortenings? I did.
They're made via a process called interesterification, which turns triglycerides solid at room temp.

Interesterified fats may be no more safe than trans fats, and may be responsible for a rise in cardiovascular deaths since 2011.

ncbi.nlm.nih.gov/labs/pmc/artic…
Unfortunately, no one seems to know how much of this stuff is being used, but it appears to be in lots of processed foods, especially baked goods.

They increase blood viscosity leading to increased thrombosis (blood clotting).
Read 7 tweets
17 Nov
Men have ~5 times the rate of heart attack and heart disease in middle age, compared to women.

Hypothesis is that it's due to rheological properties of blood, and that regular blood donation can fix this. Image
Essentially, women have blood that has a higher proportion of newer RBCs, as do blood donors.

content.iospress.com/articles/clini…
Direct relation between blood viscosity and insulin resistance.

Idea is that high viscosity means blood can't properly perfuse muscle, which is where 80% of glucose goes. pubmed.ncbi.nlm.nih.gov/9535148/
Read 14 tweets
9 Nov
So-called Blue Zones, in addition to being cherry-picked for an agenda, are concentrated in regions with no birth certificates and short lifespans.

In other words, much of what's "known" about Blue Zones could be fraud. Image
"Surveying the ‘blue zone’ of Ikaria, Chrysohoou et al. observed that the oldest-old have... a 10% illiteracy rate, an average 7.4 years of education, and a 99% rate of smoking in men."

IOW not believable as a have for supercentenarians.

biorxiv.org/content/10.110…
*haven
Read 4 tweets
10 Oct
SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: Implications for microclot formation in COVID-19

Fibrin resistant to fibrinolysis (clot dissolving) is a feature of many inflammatory diseases.
medrxiv.org/content/10.110…
Iron is involved in both hypercoagulation and hypofibrinolysis

Free iron does this but level of free iron depends in part on total body iron.

academic.oup.com/ib/article-abs…
Amyloid blood clots, i.e. abnormal clots, are seen in both type 2 diabetes and Covid

link.springer.com/article/10.118…
Read 4 tweets

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