We’re here to set the record straight on spike proteins.

Here’s why the spike proteins generated via the vaccine are safe, activate an effective immune response, and are *not the same* as the spike on the virus.

🧵[1/13]

#ScienceUpFirst Misinformation continues to spread about spike proteins. Let
First, a little Spike Protein 101

Spike proteins live on the surface of SARS-CoV-2

The virus infects human cells by binding to receptors. Once attached, the spike protein changes shape, letting the virus infiltrate our cells.



🧵[2/13]

#ScienceUpFirst
But mRNA vaccines teach our body to make a *modified spike protein*

- This triggers an immune response that teaches our bodies to protect against real SARS-CoV-2 infection.

🧵[3/13]

#ScienceUpFirst
Now let’s get into the myths about the Spike protein:

Myth: “The vaccine spikes are the same as the ones on the virus”

Reality: The spike proteins via vaccines are different from the ones found on the surface of the SARS-CoV-2.

🧵[4/13]

#ScienceUpFirst
Viral spike proteins can shape-shift. Vaccine-generated spike proteins cannot.

- When the viral spike protein fuses to human host cells, it changes shape. Think of it as two phases: pre-fusion and post-fusion. Pre-fusion: short. Post-fusion: long (1).

🧵[5/13]

#ScienceUpFirst A diagram of a short pre-fusion spike and a long post-fusion
Why does the vaccine-generated spike protein not change shape?

- It’s modified to lock into its pre-fusion form with the addition of molecules that keep it in place (2).

🧵[6/13]

#ScienceUpFirst
Myth: “Spike proteins from mRNA vaccines “burst” red blood cells”

Reality: A COVID-19 infection can damage red blood cells. This can lower levels of oxygen in the blood (3). The vaccine does not damage red blood cells.

🧵[7/13]

#ScienceUpFirst
One study has found tiny amounts of spike protein in the blood following the first dose of an mRNA vaccine (4).

Misrepresentations of this study suggest the vaccine somehow harms red blood cells. There is no evidence of this.

🧵[8/13]

#ScienceUpFirst
Myth: “Spike proteins from COVID vaccines are damaging organs.

Reality: Viral spike proteins can damage organs. Vaccine-generated spike proteins cannot.

🧵[9/13]

#ScienceUpFirst
A study has found that *viral spike proteins* can promote lung and artery injury (5).

But, there is no evidence to suggest that vaccine-generated spike proteins damage organs.

🧵[10/13]

#ScienceUpFirst
Myth: “Spike proteins from vaccines harm your ovaries”

Reality: No ovary damage from vaccines. Data on lipids, not spike proteins, is being misrepresented (6).

There is no evidence that the COVID-19 vaccine harms ovaries or fertility.

🧵[11/13]

#ScienceUpFirst
- Vaccine generated spikes are *not* the same as the ones on the virus
- Vaccine generated spikes are safe
- Vaccine generated spikes activate an effective immune response
- Vaccine generated spikes do not harm your organs, red blood cells, or ovaries

🧵[12/13]

#ScienceUpFirst Bed time for spike protein rumours:  Review:  - Vaccine gene
Need even more Spike Protein content?! We have just the post for you:

Questions about vaccines? Leave a comment or send us a DM!

References: tinyurl.com/SUFSpikeDebunks

🧵[13/13]

#ScienceUpFirst

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More from @ScienceUpFirst

19 Nov
What are the differences between the vaccine for people 12+ and the vaccine for those 5-11?

Check out our quick guide!

🧵 [1/8]

#ScienceUpFirst Comparing the Pfizer-BioNTech vaccines  Adult vaccine, for p
Both vaccines are safe and effective. ✅💉

Both use mRNA as the active ingredient. ✅💉

What’s different?

🧵 [2/8]

#ScienceUpFirst
The colour of the vial cap is different. 👀

- 12+ vial has a purple cap 🟣

- 5-11 vial has an orange cap 🟠

🧵 [3/8]

#ScienceUpFirst
Read 8 tweets
19 Nov
Health Canada approved the Pfizer-BioNTech vaccine for kids 5-11 today. 🥳

NACI has also provided recommendations on how best to use the vaccines, including dose interval.

Let’s discuss why they recommend at least 8 weeks between doses.

🧵 [1/7]

#ScienceUpFirst Why at least 8 weeks between COVID-19 vaccines for kids?  (N
You may have noticed that Health Canada authorized the COVID-19 vaccine with doses 3 weeks apart. But NACI is recommending doses at least 8 weeks apart.

@GovCanHealth: canada.ca/en/health-cana…

NACI: canada.ca/content/dam/ph…

Why the difference?

🧵 [2/7]

#ScienceUpFirst
Health Canada authorizes vaccines based on clinical trial data. Pfizer tested the vaccines with 3 week intervals, so that’s what Health Canada approved. ✅

🧵 [3/7]

#ScienceUpFirst
Read 7 tweets
19 Nov
BREAKING: Health Canada authorizes use of the Pfizer-BioNTech COVID-19 vaccine in children 5 to 11 years of age. 💉

Keep reading for more information.

🧵 [1/8]

#ScienceUpFirst This just in: Health Canada authorizes use of Pfizer-BioNTec
Health Canada has completed a thorough and independent scientific review of the evidence. They have determined that this vaccine is safe and effective at preventing COVID-19 for children between 5 and 11 years of age.

🧵 [2/8]

#ScienceUpFirst
In the Phase 2/3 clinical trial, the Pfizer-BioNTech vaccine was 90.7% effective at preventing symptomatic #COVID19 in children 5 to 11 years of age.

This is great news for the 2.88 million children aged 5 to 11 in Canada. 👏

🧵 [3/8]

#ScienceUpFirst
Read 8 tweets
10 Nov
Have questions about long COVID? Well we’ve put together a looooong thread to answer them!

Here’s what we know about Long COVID so far.

References at the end!

🧵 [1/13]

#ScienceUpFirst Long COVID  (While most fully recover from COVID-19, some pe
“Long COVID” is the name coined by patients, often referred to as "long haulers."

Other terms include “post COVID-19 condition” by the WHO and “post-acute sequelae of COVID-19 (PASC)” by the CDC.

They all refer to versions of the same condition.

🧵 [2/13]

#ScienceUpFirst
.@GovCanHealth's definition:

“Symptoms persisting or recurring for weeks after acute COVID-19 illness... further broken down into:

- post COVID-19 conditions occurring 4-12 weeks (short term)
- and >12 weeks (long-term) after COVID-19 diagnosis.”

🧵 [3/13]

#ScienceUpFirst
Read 13 tweets
3 Nov
On the fence about fighting the flu? 🤔

Well get off the fence and get on defense! Getting the flu shot is extra important this year. Keep reading to find out why.

References at the bottom of the thread!

🧵 [1/10]

#ScienceUpFirst Flight the Flu!  (During a pandemic, it is extra important t
Silver lining to 2020? The flu season was very mild (1). We can thank public health measures like physical distancing, reduced travel, masks and hand-washing for that.

Here’s why things are different this year...

🧵 [2/10]

#ScienceUpFirst
Reason 1: We’re seeing more people face to face. (Yay!) 👭

Reason 2: Low flu rates during the past two seasons means our population immunity against influenza is lower than usual (2). (Not yay!) 🤒

🧵 [3/10]

#ScienceUpFirst
Read 10 tweets
2 Nov
Side of fries? 🍟 Yes!
Vaccine side effects? 💉 Pass!
Luckily, neither last long.

Keep reading to learn why doctors are confident in the safety of the COVID-19 vaccines, even long term.

Refs at the end!

🧵 [1/12]

#ScienceUpFirst Concerned about long-term side effects of the COVID-19 vacci
Medications can have long-term effects, but vaccines work differently.

Medication is often taken daily for years.

Vaccines are given infrequently. For COVID-19, this means 1 or 2 doses, and then possible future boosters.

🧵 [2/12]

#ScienceUpFirst
If you take certain medications every day, side effects may occur over time.

Vaccine ingredients don’t stick around your body. They drop in, chat with your immune system, and then disappear. We’re talking minutes to hours (3)!

🧵 [3/12]

#ScienceUpFirst
Read 12 tweets

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