BSL-3 lab leak in Taipei
She was exposed to the virus in mid November
No symptoms until late in month, meanwhile went all over Taipei before finally getting tested.
Could it have started like this at a Wuhan lab?
taiwannews.com.tw/en/news/4371080
h/t @keverington
She was exposed to the virus in mid November
No symptoms until late in month, meanwhile went all over Taipei before finally getting tested.
Could it have started like this at a Wuhan lab?
taiwannews.com.tw/en/news/4371080
h/t @keverington
Taiwanese language News via @Ayjchan
"Preliminary study concluded that the work site was contaminated & infected"
"Because the case has no recent history of going abroad, it is preliminary speculated that he may have been infected in the laboratory"
cna.com.tw/news/firstnews…
"Preliminary study concluded that the work site was contaminated & infected"
"Because the case has no recent history of going abroad, it is preliminary speculated that he may have been infected in the laboratory"
cna.com.tw/news/firstnews…
The BSL3 Lab Barn Door will be closed tomorrow..
Commander Chen Shizhong announced on the 9th that it would be closed and suspended, and all personnel in the third laboratory building would be suspended on the 10th.
cna.com.tw/news/firstnews…
Commander Chen Shizhong announced on the 9th that it would be closed and suspended, and all personnel in the third laboratory building would be suspended on the 10th.
cna.com.tw/news/firstnews…
The outside world (@keonieverington & #DRASTIC for example) is curious about whether the case was bitten by experimental mouse causing infection. Zhang Shangchun said that the internal investigation did indeed cause the bite, but he was not sure whether it caused the infection 
Chen Shizhong pointed out there have been no local cases for 34 consecutive days
The possibility of infection abroad is low, and there is a risk of exposure to pathogens in the workplace
So it is judged to be a local case infected with Delta mutant strain
cna.com.tw/news/firstnews…
The possibility of infection abroad is low, and there is a risk of exposure to pathogens in the workplace
So it is judged to be a local case infected with Delta mutant strain
cna.com.tw/news/firstnews…
The Lab in question - Nangang P3 Lab in Beishi City
The work of the P3 lab includes new coronavirus cultivation, assistance in the development of new coronavirus neutralizing antibodies,etc
Mentions 18 other BSL3 Labs?
cna.com.tw/news/firstnews…
The work of the P3 lab includes new coronavirus cultivation, assistance in the development of new coronavirus neutralizing antibodies,etc
Mentions 18 other BSL3 Labs?
cna.com.tw/news/firstnews…
Good Attitude to Lab Biosafety in Taiwan
"personnel must read a thick stack of manuals, and conduct drills and exams every six months, and issue training certificates...but as long as it is a human, it is inevitable to make mistakes..a slight omission may make a mistake"
"personnel must read a thick stack of manuals, and conduct drills and exams every six months, and issue training certificates...but as long as it is a human, it is inevitable to make mistakes..a slight omission may make a mistake"
Biosafety Quote from:
cna.com.tw/news/firstnews…
"However, Shi Xinru emphasized that lab management shouldn't be afraid of mistakes & more importantly, admit & propose ways to review & improve. Checking which link is wrong can be a warning to avoid similar incidents in other labs"
cna.com.tw/news/firstnews…
"However, Shi Xinru emphasized that lab management shouldn't be afraid of mistakes & more importantly, admit & propose ways to review & improve. Checking which link is wrong can be a warning to avoid similar incidents in other labs"
Taipei Mice
"Upon virus challenge, generated AAV/hACE2 mice showed pathophysiology closely mimicking the patients with severe COVID-19. "
Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19
journals.plos.org/plospathogens/…
"Upon virus challenge, generated AAV/hACE2 mice showed pathophysiology closely mimicking the patients with severe COVID-19. "
Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19
journals.plos.org/plospathogens/…
1/. The SARS-CoV-2 used in this study was the clinical isolate TCDC#4(hCoV-19/Taiwan/4/2020)
2/. All mouse challenge experiments were conducted in the animal biological safety level 3 (ABSL-3) facility at Genomics Research Center, Academia Sinica.
2/. All mouse challenge experiments were conducted in the animal biological safety level 3 (ABSL-3) facility at Genomics Research Center, Academia Sinica.
I see these two strains mentioned frequently by Academia Sinica's Genomics Research Center
SARS-CoV-2 strains used in this study are clinical isolates of WT strain (hCoV-19/Taiwan/4/2020) & Delta variant (hCoV-19/Taiwan/1144/2021)
jbiomedsci.biomedcentral.com/articles/10.11…
SARS-CoV-2 strains used in this study are clinical isolates of WT strain (hCoV-19/Taiwan/4/2020) & Delta variant (hCoV-19/Taiwan/1144/2021)
jbiomedsci.biomedcentral.com/articles/10.11…
Confirmed BSL3 mouse attack in Taipei
@TaiwanNews886 Story by @keonieverington
Scientist bitten by mouse in Taipei lab before testing positive for COVID
CECC confirms scientist bitten by lab mouse while experimenting on different COVID variants
taiwannews.com.tw/en/news/4371212
@TaiwanNews886 Story by @keonieverington
Scientist bitten by mouse in Taipei lab before testing positive for COVID
CECC confirms scientist bitten by lab mouse while experimenting on different COVID variants
taiwannews.com.tw/en/news/4371212
More Relevant Academia Sinica Research
We thank Taiwan CDC for providing SARS-CoV-2 TCDC#4 (hCoV-19/Taiwan/4/2020) & funding support from Academia Sinica for P3 facility
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro
sciencedirect.com/science/articl…
We thank Taiwan CDC for providing SARS-CoV-2 TCDC#4 (hCoV-19/Taiwan/4/2020) & funding support from Academia Sinica for P3 facility
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro
sciencedirect.com/science/articl…
Some Names of Researchers at Academia Sinica's Genomics Research Center/ and Institute of Biomedical Sciences (IBMS), BSL3 facility in Taipei
Lab worker in her 20s resigned on Dec 3rd
"she resigned on Dec 3 & the reason for her resignation is also part of the investigation"
udn.com/news/story/120…
"She had light cough on Nov 26, coughing intensified on Dec 4 & abnormal smell & taste on Dec 8"
cnews.com.tw/003211209a12/
"she resigned on Dec 3 & the reason for her resignation is also part of the investigation"
udn.com/news/story/120…
"She had light cough on Nov 26, coughing intensified on Dec 4 & abnormal smell & taste on Dec 8"
cnews.com.tw/003211209a12/
a British mutant mouse? 🐭🇬🇧
"A local case appeared today, a former female researcher in the P3 laboratory of the Academia Sinica, and even reported that it was bitten by a British mutant mouse."
udn.com/news/story/120…
"A local case appeared today, a former female researcher in the P3 laboratory of the Academia Sinica, and even reported that it was bitten by a British mutant mouse."
udn.com/news/story/120…
Alpha and Gamma Variant Claims
She was bitten twice on October 15 and November 19, respectively
However, Academia Sinica now claims that the Experimental mice were infected with Gamma and Alpha strains
tw.news.yahoo.com/%E4%B8%AD%E7%A…
Researcher infected with Delta Strain...
She was bitten twice on October 15 and November 19, respectively
However, Academia Sinica now claims that the Experimental mice were infected with Gamma and Alpha strains
tw.news.yahoo.com/%E4%B8%AD%E7%A…
Researcher infected with Delta Strain...
Not only viciously bitten twice by furious mice but also bullied for reporting the mouse attacks?
It is rumored that the infected female assistant was reportedly bullied by the dean of the Academia Sinica after reporting through the Lab SOP
chinatimes.com/realtimenews/2…
It is rumored that the infected female assistant was reportedly bullied by the dean of the Academia Sinica after reporting through the Lab SOP
chinatimes.com/realtimenews/2…
Alpha, Gamma, Delta, Mouse
Research assistant bitten by mouse with British mutant Alpha virus
Second mouse had Brazilian mutant Gamma
She was diagnosed with Indian mutant Delta
People are being investigated first
Mice have not yet been investigated!
tw.appledaily.com/life/20211210/…
Research assistant bitten by mouse with British mutant Alpha virus
Second mouse had Brazilian mutant Gamma
She was diagnosed with Indian mutant Delta
People are being investigated first
Mice have not yet been investigated!
tw.appledaily.com/life/20211210/…
Why is there a blurred dead Spiderman next door?
What are these lab workers trying to hide..?
nownews.com/news/5470048?u…
What are these lab workers trying to hide..?
nownews.com/news/5470048?u…
6 contractors for the P3 Lab negative pressure system filter entered from Dec 7 to 9 to replace the filters but got no instructions how to cooperate with epidemic prevention work.
"Why no one noticed us, nobody notified us, and we don't know what to do!"
nownews.com/news/5470486?u…
"Why no one noticed us, nobody notified us, and we don't know what to do!"
nownews.com/news/5470486?u…
Don't Worry, Be Happy!
The personnel of Academia Sinica stated that the negative pressure system of the P3 laboratory is independent, so please don't worry.
This made the supervisor quite worried,
"How should outsourcing vendors do it?"
nownews.com/news/5470486
The personnel of Academia Sinica stated that the negative pressure system of the P3 laboratory is independent, so please don't worry.
This made the supervisor quite worried,
"How should outsourcing vendors do it?"
nownews.com/news/5470486
Update - Nasty little mealy mouthed article from Global Times in Mainland China via @gdemaneuf
Scientist in Taiwan contracts COVID-19 after P3 lab exposure, repeats SARS mistake
Scientist in Taiwan contracts COVID-19 after P3 lab exposure, repeats SARS mistake
https://twitter.com/gdemaneuf/status/1469448870321029120
Update via @keverington
Lab Infection with Delta Variant confirmed
Probably via mouse bites
taiwannews.com.tw/en/news/4372853
Lab Infection with Delta Variant confirmed
Probably via mouse bites
taiwannews.com.tw/en/news/4372853
Let's finish this thread with some great satire from @gdemaneuf
https://twitter.com/gdemaneuf/status/1469572369400295427
Unroll @threadreaderapp
Taipei double mouse attack
Delta VOC Infection of young lab researcher
who got bullied by her bosses
but at least there was great transparency demonstrated by Taiwan
which contrasts dramatically with the Chinese response in Wuhan back in December 2019
Taipei double mouse attack
Delta VOC Infection of young lab researcher
who got bullied by her bosses
but at least there was great transparency demonstrated by Taiwan
which contrasts dramatically with the Chinese response in Wuhan back in December 2019
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