I see that the media has started to do its telephone-game thing of slowly exaggerating reality with each successive report.
I did not say that SARS-CoV-2 was genetically engineered. I said that it is reasonable to hypothesize and investigate if it was genetically engineered.
I've even seen some media reporting that I've found evidence of a lab #OriginOfCovid
This is similar to what happened when @MichaelWorobey published his @ScienceMagazine letter, which became reported as a US scientist finding evidence of patient zero at the seafood market.
The context of my statement has not been reported. The @CommonsSTC asked its witnesses to provide a % likelihood estimate for natural vs lab #OriginOfCovid
Richard Horton went first and said he favored the @WHO view that lab origin is extremely unlikely.
@CommonsSTC@WHO I countered that a lab origin seems more likely.
The situation remains that no dispositive evidence has been reported for either natural or lab #OriginOfCovid Both remain plausible & worthy of a credible investigation. Neither investigation should be prioritized above the other.
@CommonsSTC@WHO If any reporters watched the actual session, the @CommonsSTC@mattwridley and I clearly said that we are only considering an accidental lab escape, not a bioweapon.
We don't say genetically engineering is likely, just that it must and can be investigated.
@CommonsSTC@WHO@mattwridley I also press my point to @CommonsSTC that it should be a priority to obtain original manuscripts, whether withdrawn, rejected or published, from our scientific journals so that we can get a better understand of the beginnings of the pandemic.
An addendum to the Proximal Origin letter published in @NatureMedicine is long overdue. I still see people citing this paper with little awareness of how this letter came to be and problems with both its origin and content. nature.com/articles/s4159…
The addendum should clearly explain and address the following 3 issues:
1. Proximal Origin was the product of a private meeting in Feb 2020 among Western leaders in research/funding. Phone call Feb 1. First draft of Proximal Origin Feb 4.
Experts who provided (redacted) feedback on the manuscript were not acknowledged in the @NatureMedicine letter. The only expert thanked for contributing to discussions is M. Farzan.
To expand on a point in my recent @StatedClearly interview:
"Science cannot be embodied by one person or even a group of people... It’s not something where a pandemic happens and only virologists can have the answer."
@StatedClearly That SARS-CoV-2 spreads through the air is perhaps one of the top 3 most important facts that needed & still needs to be acknowledged to limit covid spread.
It would've saved potentially millions of lives if this simple fact had been clearly explained to the world in early 2020.
Yet, it took until August 2021, more than a year and a half post-covid for a review on this topic to be published in a prominent scientific journal.
Of the 7 authors, only 1 is a virologist. The majority are aerosol or bioengineering experts. science.org/doi/10.1126/sc…
A strawman argument from natural #OriginOfCovid proponents is that scientists would've engineered a textbook cleavage site into novel SARS-like viruses in the lab.
But, if you read their research proposal, the scientists said they would engineer in rare, novel cleavage sites.
The scientists had a pipeline in early 2018 for detecting never-seen-before cleavage sites in rare SARSrCoVs & engineering these into SARSrCoVs in the lab.
There's no reason why novel cleavage sites should look like the ones in our textbooks.
Lots of buzz about the new preprint about rare furin cleavage sites in the spikes of European bat SARS-like viruses. Difficult to say much until the spike sequences obtained within this study are deposited in GenBank and released. biorxiv.org/content/10.110…
It is likely that scientists on the other side of the world had encountered similar rare furin cleavage sites in the SARS-like viruses they had found, which led them to write the following in the 2018 DEFUSE proposal:
"We will also review deep sequence data for low abundant high risk SARSr-CoV that encode functional proteolytic cleavage sites, and if so, introduce these changes into the appropriate high abundant, low risk parental strain."
And he's in great company! Several top virologists have expressed that a genetically engineered origin of SARS-CoV-2 is plausible and should be investigated.
We know that the Wuhan Institute of Virology had access to bat pathogen samples in Laos, from the emails and research reports FOIA'ed and from their very own data deposited in NCBI.