At this point, the US should have 4 times more immunity than SouthAfrica: 3 times more people have already had COVID in the US; our vaccination rate is more than double theirs.
But our current death rate is running 4 times higher. Why? 1/
I really don't know
3 possible reasons:
a) Differences in demographics & co-morbidities (although with prior waves, their deaths have tracked ours)
b)Inaccurate case ascertainment: they may have had far more people with prior Covid than has been reported
c) Different variants
2/
Many have pointed to the low death rate now in South Africa with the Omicron wave as an indication that Omicron is milder.
But I think our problem in the US is different: we are facing delta plus omicron. Not just omicron.
3/
Our capacity to take on more new cases is low, regardless of whether omicron is mild or not.
So as cases rise we just have to be careful and take precautions because for whatever reason, we are on a different trajectory. So don't look at South Africa for comfort.
4/
What about other countries in Africa? That's a question for another day. A different mystery.
Most African countries look 180 different than either the US or South Africa. 5/
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When all is said and done, COVID vaccines have taken the sting out of COVID.
This is seen in cases versus deaths in UK: Deaths lower this time around even though cases skyrocket. Vaccines work.
Also seen in the US but not as striking as in the UK probably because a) heterogeneity: some states are doing like UK, some worse; b) we are not as well fully vaccinated (60% vs almost 70% UK); c) UK had a bigger death toll in January; d) they are ahead of us in the omicron wave.
This is even better illustrated in countries that are much more fully vaccinated than the US or UK. Note how deaths have stayed low with recent waves even as cases went up.
In the global race to vaccinate against COVID, the US is lagging behind most developed countries. ig.ft.com/coronavirus-va…
In fact, countries which have lower vaccination rates than us are mainly those with inadequate access to vaccines.
Overall we are at #93 of about ~225 countries in %fully vaccinated. Excluding small countries with less than 200,000 population, we are at still >#60 in the race.
This is not due to limited vaccinate availability but vaccine hesitancy.
Vaccine hesitancy is not due to a uniform cause. There are many reasons. But mostly it is due to misinformation about Covid and Covid vaccines spread on media and social media.
Without leading a trial it's hard for you to realize how hard it is to do one and you may end up throwing stones at investigators trying to do their best. #ASH21
See this thread on how many people control the design of a trial. Most of this thread applies also to investigator initiated non randomized trials also. #ASH21
When you have this brilliant idea on how a trial should have been designed, in many cases the PI is also brilliant enough to know the same but they often had to make the hard choice of putting their foot down and not have a trial at all or compromise. #ASH21
Only in a broken system can you increase prices like this. Every time your competitor increases price you do on the same day. Because you can. Because there is no completion. Because there is no law that prevents hikes like this on the exact same product.
The price hikes succeed because there is a vulnerable population that needs the drug to stay alive and so has to spend whatever it takes. It is government that needs to step in and protect them. @t1international#Insulin4all