This systematic review and meta-analysis suggests that intermittent fasting is associated with successful weight loss and metabolic benefits among adults with obesity.
- IF as a weight loss approach was found to be mostly successful in the initial phase (ie, 1-6 months).
- Modified alternate-day fasting and the 5:2 diet were the only IF types that were associated with statistically significant weight loss of more than 5% in adults with overweight or obesity.
Here comes the fun part:
"We identified 104 associations and found significant beneficial outcomes associated with IF on BMI, body weight, fat mass, LDL-C, total cholesterol, triglycerides, fasting plasma glucose, fasting insulin, HOMA-IR, and systolic and diastolic blood pressure...
"...mostly in adults with overweight or obesity. IF was associated with reduced fat-free mass in adults with overweight or obesity...
"...Only 1 effect among 28 statistically significant associations was supported by high-quality evidence in the main and sensitivity analyses...
"...namely, the association of MADF for 1 to 2 months with reduced BMI in healthy adults and adults with overweight, obesity, or NAFLD compared with regular diet...
"...Moderate quality of evidence also existed for an association between MADF and reduced BMI and fat-free mass in adults with overweight and/or obesity compared with continuous energy restriction...
"...The other 2 associations had a moderate quality of evidence, namely, the use of zero-calorie ADF for the reduction of fat mass and the 5:2 diet for the reduction of fasting insulin in adults with overweight or obesity...
"... compared with continuous energy restriction and/or regular diet."
Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials (open access)
doi.org/10.1001/jamane…
#weightloss #IntermittentFasting
doi.org/10.1001/jamane…
#weightloss #IntermittentFasting
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