After working several days in a row in the ER, can reasonably say a few things.
Omicron definitely is more mild... for the vaccinated. Unlucky folks on the older end or with comorbidities can get it more severely though.
For the unvaxxed, same deadly virus. No doubt about that.
The symptoms have changed as well.
Before the hallmarks were loss of taste and smell, severe body aches, chest pain and shortness of breath,
Now most (vaccinated) people present with a sore throat, runny nose, mild cough for a few days.
Last night, of around 45 PCR swabs we ordered,every single one was positive for Covid.
If you have cold or flu-like symptoms in Toronto now, you have to assume it is likely Covid regardless of what a rapid test or PCR tells you.
One trend I see is that it seems to be hitting kids, who are largely unvaccinated, more.
Plans to reopen schools need to take into account that this cohort still hasn't had a chance to be fully vaccinated, especially the under 5's where no vaccine is approved at all.
Still unknown is the rate of Long Covid for those that get a mild vaccine-breakthrough infection. We won't know this for a few weeks.
Also, maybe there's a correlation between how recent the last vaccine dose was and the severity of symptoms. Need more data though.
Omicron's relative mildness for me is not a cause to celebrate. We took a huge risk allowing it to propagate, can you imagine what would have happened if it was more severe?
Demand by the unvaxxed alone will roil our system for months to come.
There's no guarantee the next variant will be merciful to us. Another few mutations, mixed in with unfettered air travel and we start this all over again. We should prepare while we can:
Every household should have a box of N95s and rapid tests, every shop, school and restaurant should have a ton of HEPA filters. When something terrible comes our way, our 'shields' go up, but we still live life. In peacetime we can relax our guard.
The worst outcome is if we just accept this is 'endemic' This is a nightmare future where we face this 'Superflu' regularly... our immune systems just aren't good at fighting Covid... many will die or be disabled. Mild SARS is still SARS in the end. We need to be proactive.
A reminder that a 'mild' infection may not be a walk in the park for many people. There's no way to predict which way it will go for any of us.
I'm making rapid test 5-packs for my clinic patients. Also throwing in a KN95 mask to protect them from day-to-day airborne exposures. I figure if governments won't do it, it's up to all of us to jump in and protect each other this holiday season from Omicron.
I was fortunate to have a local business donate the tests. Was inspired by @LisaBarrettID's work in Halifax; 11 drops of the reagent in each vial, instructions, 5 test strips, and a mask in a sandwich bag. Feel free to do the same for your customers and patients!
This is the way it should be, and we don't have much time:
Tomorrow vaccine approval is expected in Canada for kids 5-11. I believe so strongly in their benefits that I enrolled my own sons in a trial of @moderna_tx's vaccine for kids 6m to 5y. They have a 1/4 chance of getting a placebo, but🤞they have some chance at safety now. 🧵=>
The evidence thus far is that it is safe and effective for children. It reduces the risk of infection, and though death is rare, it still happens in 1/10k cases. Long Covid can happen in >1/50 cases. @EricTopol lays it out plainly here:
In this detailed thread @ENirenberg goes over data presented at recent FDA and CDC meetings. Myocarditis is thought to affect males pubertal age and above, and resolves quickly. The CDC advisory committee voted unanimously to recommend the vaccine:
Covid is an airborne virus. What does that mean and how can you protect yourself from it? I go over some practical steps you can take to keep yourself safe this winter with @gilldeacon on @CBCHereandNow: cbc.ca/listen/live-ra…
Step 1: Whenever you go in an indoor space, make sure you have the right protection. A well fitting N95 or similar mask is your superpower. It frees you from worrying if others are wearing their masks properly, and if they are vaccinated. I don't go indoors anywhere without one.
This is a guide to wear you can buy an N95 equivalent mask, typically $1 or so at major stores, and you can re-use them several times.
I'm going to be speaking on @CBCHereandNow today at 5:50pm (ET) about how you can protect yourself from airborne spread of Covid-19. Airborne virus particles can linger in the air for hours, and infect you if you don't have a good mask or if the space is not well ventilated.
With all of us spending more time indoors, the quality of ventilation is all important. Make sure your workplace, school or shop are paying attention to this. Go into poorly ventilated spaces only with a good quality N95 mask or similar:
We can't live with Covid any more than we can live with measles, polio, smallpox, malaria, chemical, biological and nuclear weapons. These are all things that have been controlled with sustained effort over multiple generations.
Today many hospitals in the Toronto area will start to offer the Regeneron Monoclonal cocktail for the treatment of Covid-19. This is a ‘passive vaccination’ - providing artificial antibodies that otherwise develop naturally in vaccinated people.
I went over in some detail how these treatments are created last year. They are produced in a process that shares many steps with production of mRNA vaccines. One of them, @AbCelleraBio's Bamlanivimab, is designed in Canada and marketed by Eli Lilly.
They also represent a crucial part of an ‘immune system for society’ where we can handle new threats and variants that evade our vaccines. These are local companies that are going to help us fight these threats: @IncResilience@AbCelleraBio@PrecisionNano@Novavax@medicagoinc