The most disheartening part of this pandemic has been scientists who've been repeatedly wrong, driving policies that've led to loss of life & suffering blaming those who've argued for mitigations throughout as being 'pro-lockdown' when they've done everything to prevent this. 🧵
The worst part of this is that the scientists who argued for sensible measures never had any influence or power- not in SAGE, not outside SAGE. They were consistently ignored. Who were listened to? Heneghan, Gupta, and now Balloux. But sure, blame those who wanted to save lives.
The reason we've needed lockdowns is because of the normalisation of mass infection carried out by groups like HART, UsForThem, GBD proponents, and Global collateral. They've had preferential access to MPs who have parroted their points to justify mass infection.
So when you look at the >170,000 dead, and 1.2 million with long COVID, including 77,000 children of whom 14,000 have now been ill more than a year - don't you dare call those who argued to prevent this 'pro-lockdown', or people who don't care about the disabled and vulnerable.
This suffering in pain is yours to own.
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An amazing study led by @emcat1 carefully dissecting the properties of omicron relative to other variants. TL;DR:
omicron shows:
-high levels of escape from vaccines with immunity partly restored post-3rd dose
-lower syncytia formation
-different preferred mechanism of cell entry
First, the study predictably showed large reductions in neutralising antibodies for omicron compared to the original variant for all vaccines, with absolute levels lowest for AZ, and higher for both mRNA vaccines (highest for Moderna, and then Pfizer)
Boosting increased neutralising antibody titres, esp for those who had received 2 doses AZ, where this seems essential to partly restore immunity. Not sure what this means, but those with initial AZ boosted with mRNA had a higher proportion with measurable immunity (62% vs 25%).
Those who've opposed basic mitigations in schools & vaccines in kids have done this by default, because this is what's led to mass educational disruption for many kids, and unacceptable risks for clinically vulnerable households. It's not open vs closed. It's about opening safely
No one wants schools closed- but they've had to because infection rates got to such heights that they became unsafe. That's why we've got to advocate to make them safer, so *all* children, including those in CV households can stay in school. Anything less is discriminaory.
I had no choice to take my daughter out of school over December, due to a large outbreak in school, very few mitigations & us being a CV household. I want her to be able to enjoy school like other children & get the best education. But the risk was too high. We need to do better.
Myth debunking:
After reading more misleading takes in the media, I'm going to try to explain this again- overall, omicron causes *more* and not less severe disease than delta - even at an individual level for most people. Why? 🧵
Your risk of getting hospitalised with SARS-CoV-2 (any variant) depends on two things? 1. how likely are you to get infected? 2. what is your chance of getting hospitalised *once infected*
In simple terms, because omicron can escape immunity from past infections and vaccines, your protection against infection against omicron is vastly lower than with delta. This means risk of 1. is vastly increased- as you're less protected & also v. high background transmission.
Nonsense- had we let infection spread to let 'immunity build in the population' hundreds of thousands of people would've died, much before getting a chance to be vaccinated! It's your constant campaigning against migitations that have led to policies that led us into lockdown.
The John Snow Memo exposed GBD as dangerous pseudoscience - it's time to admit this and apologise because you and others got it so badly wrong, but have continued to advocate for policies that have harmed both public health & economy.
Who are these 'lockdowners'? Certainly not those who've been asking for airborne precautions and good public health strategies throughout the pandemic. It's the people who've advocated for letting infection spread, which led to crises then requiring lockdowns.
On BBC London just now challenging the 'mild' narratives. Takeaway: please stop blaming the scientific community for changing narratives in the media! That's down to media (assisted by some scientists with a track record of minimisation).
From 17:12 bbc.co.uk/sounds/play/li…
Omicron is a serious threat- it was before & it is now. As we get more information, we will be able to refine the level of threat more, but the data from yesterday doesn't at all mean that it's not a serious threat!!! If media has portrayed it that way, that's on them.
I'm actually really frustrated by the media rhetoric targeting scientists, and suggesting the public are frustrated with scientists for changing narratives and evidence. Evidence will change, but the way it's been portrayed in media does create whiplash, because it's misleading!
Some brief thoughts on the concerning relativism I've seen creeping into media, and scientific rhetoric over the past 20 months or so - the idea that things are ok because they're better *relative to* a point where things got really really bad. 🧵
Many pointed to summer in the UK saying it was a success because 'freedom day' didn't translate to anything like Jan 21 or March '20. No it didn't, but >18000 people died since (many deaths may have been avoided with simple measures like mask mandates, mitigations in schools)
And of course we have 1.2 million with long COVID with children seeing a doubling in 4 months. But all this is okay, because it's not as bad as Jan, or March last year. When the pandemic hit in March, we were thoroughly unprepared.