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Marion Holman Profile picture
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29 Dec, 4 tweets, 1 min read
1/4 Ethan Weiss on Statins: Not sure if to laugh or cry. "And the statin trial comes with an important condition: the drug must not make people feel bad. I tell patients that statins are probably the best studied class of medicines in history" 😂😂😂
2/4 "My read of the data suggests that they are safe (they will not cause adverse events) except small effects on blood sugar which are real but small. I tell people that we will focus then on tolerability"
3/4 My thoughts: What planet does he inhabit ? He hasn't read the data, or he hasn't understood it, he has absolutely no idea about the mechanism of action of Statin drugs, and no clear idea about what actually causes heart disease. This guy lives in cloud cuckoo land.
4/4 However, keep pushing cell toxins that trash cell membranes onto your patients, and focus on tolerability. When the muscle damage/pain gets too bad, just take a short Statin holiday and re-challenge. Welcome to the world of idiots !!!

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More from @holmanm

Marion Holman Profile picture
30 Dec
1/4 So sad for these poor souls who still believe that ⬇️ Cholesterol = good health. “I started taking Repatha last July. I had been previously taking Lipitor. I had side effects especially muscle pain and joint pain. I had been stopped for about 5 months.
2/4 My current Cardiologist said I should try Repatha due to the low number of reported side effects. During second months injections (every two weeks) I felt mild muscle pain and weakness. I took Tylenol to help with the pain. It has become progressively more insidious.
3/4 Yesterday, 5 days from last injection I could not get out a chair, running nose, trouble walking, can't go up and down stairs, severe pain in ankles, knees, hips and back. loss of upper body strength, itching.
Read 4 tweets
Marion Holman Profile picture
30 Dec
1/9 Chronic inflammatory diseases, such as rheumatoid arthritis, lupus, psoriasis, and infections, such as periodontal disease p.gingivalis & HIV, are associated with an increased risk of CVD. Patients with these disorders also have an increase in coronary artery calcium
2/9 measured by CT & carotid intima media thickness measured by ultrasound. WHY ?? Because inflammation & infections induce a variety of alterations in lipid metabolism that may initially DAMPEN inflammation or fight infection, but if chronic could contribute to the increased
/3
3/9 risk of atherosclerosis. The changes in lipids and lipoproteins that occur during inflammation & infection are part of the innate immune response & therefore are likely to play an important role in PROTECTING the host.
/4
Read 10 tweets
Marion Holman Profile picture
29 Dec
1/7 Read this, read it again, and understand it.
To me it is mindblowing. It points to the fact that lipids are PROTECTIVE. Part of the innate immune response, and it makes the 'infective cause' of CVD far more plausible.
2/7 Lipoprotein particle levels and their constituents are extensively altered by acute inflammation and infection (Gabay and Kushner, 1999). In fact, hypocholesterolemia (low cholesterol) has been consistently correlated with WORSE outcomes in critically ill patients
3/7 (Windler et al., 1994; Gordon et al., 2001; Gui et al., 1996; Marik, 2006). The molecular mechanisms underlying this are poorly understood but measurements of various lipid parameters in patients with severe sepsis or septic shock indicate that apoB lipoprotein levels can
Read 7 tweets
Marion Holman Profile picture
24 Dec
1/4 Here is one from the heart. I just had a conversation with my Step sister. She has been on 40mg Lipitor for 18 years. During that time she has been diagnosed with Breast Cancer (hardly surprising). She has undergone a knee operation (Statin muscle damage),
2/4 a shoulder operation (rotator cuff, very common with Statin use), and more recently has been suffering from hand and food tremors. She has recently seen a Neurologist, and the diagnosis is Parkinson's disease. I have tried and tried to tell her how Statin Drugs can
3/ cause this. She just will NOT listen. I feel so bloody helpless, because I know for sure from my research on these fungal mycotoxins that they are causal in ALL her problems. She has now been given Levodopa to try and counteract the Parkinson's disease.
Read 5 tweets
Marion Holman Profile picture
23 Dec
1/7 Statins are fungal secondary metabolites which selectively inhibit (HMG-CoA) reductase, the first enzyme in cholesterol biosynthesis.
’Secondary metabolite” is the euphemism that agenda-driven scientists and drug companies use for toxic Statins.
2/7 There are many ways to lower cholesterol. There are a few poisonous food mold toxins that will do the trick if you’re willing to take the risk:

To name but two

Ochratoxin-A (lactone/UV-flourescent)
Citrinin (inverted lactone/UV-fluorescent
3/7 A friend suffering from MND/ALS after using 80mg Lipitor took the drug to an INDEPENDENT lab to get the drug tested.
Two tests on 80 mg of Atorvastatin (Lipitor) came back with Ochratoxin A and Citrinin with 39 ug/g
Read 7 tweets
Marion Holman Profile picture
19 Dec
1/4 Huge eye opener for me. Statins forum again (sorry)
"I saw the lipidologist yesterday. The first cardiologist who saw me had never seen cholesterol scores as high as mine. The cardiology fellow hadn't either. Cholesterol was something like 600 and total was around 3500.
2/4 My xanthelasma reappeared (milder than before), so these docs were able to actually look at me & see the cholesterol leaking out of my eyes. They are putting me on Zetia, since I refused statins. They told me to eat a lot less saturated fat,
3/4 and that I probably had such high numbers because of crappy genes. (Probably ?? Didn't they do a test?)
Read 4 tweets

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