Share this page!

Tracy Høeg, MD, PhD Profile picture
Twitter logo
31 Dec 21, 4 tweets, 2 min read
When considering boosters in children:
1 child/78 developed myo in the booster trial among 16-17 yos
& Pfizer's own analysis shows booster would
-prevent 29-69 hospitalizations/mill but would
-result in 23-69 vax myocarditis/mill in males 16-17
🤔Not a great ratio for most boys
Also remember myocarditis after Pfizer dose 2 & booster (and Moderna 1 &2) more common in males 16-39 than after Covid
And @MartyMakary makes an excellent point here about there not being a VRBPAC expert advisory committee meeting before the FDA authorizes boosters for 12-15 year olds
I have no problem with children having access to boosters, but certainly think families have a right to know the risks & benefits first based on their individual child's risks.
And I worry about potential booster mandates of this age group being more harmful than beneficial.

• • •

Missing some Tweet in this thread? You can try to force a refresh
　

Keep Current with Tracy Høeg, MD, PhD

Tracy Høeg, MD, PhD Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @TracyBethHoeg

Tracy Høeg, MD, PhD Profile picture
26 Dec 21
🇬🇧 The research group at Oxford who compared myocarditis rates after covid to after the vax (nature.com/articles/s4159…) have just released a new analysis:
In males 16-39,
Myocarditis more common after Pfizer dose 2 & 3
&
Moderna dose 2 than after infection medrxiv.org/content/10.110…
I'm already personally aware of 5 cases of post-booster myo in males 16-24; remember, this @NEJM study on boosters by age, the "rate of severe disease in the youngest age groups (16-39) was v low ...not enough cases to estimate the rate ratio reliably" nejm.org/doi/full/10.10…
Current college booster mandates do not seem to have the best interests of the students, especially the male students, at heart. We need better data on the risks and benefits of boosters in the <40 age group.
Read 4 tweets
Tracy Høeg, MD, PhD Profile picture
22 Dec 21
Danish 🇩🇰 data via @KT_Baek & @SSI_dk
>1/3 of all cases now omicron
No difference in case rates between vax (🔵) & unvax (🟡) in age group w/the most omicron
Prev infection (🔴) still gives some protection
So can we expect vax to protect others? 1/5
covid19danmark.dk/#gennembrudsin…
Based on data above from omicron (no diff in infection risk vax vs unvax) & from delta in @TheLancetInfDis (no significant difference in transm once infected between vax & unvax), it seems:

No, the vax can not be relied on to protect others (2/5)

But, the vaccines still appears effective against severe disease. Here are Danish data on ICU admission by vaccination status
(🟡) unvaccinated
(🔵) 2 or 3 doses
So it appears your vax protects you, not others
(3/5)
Read 5 tweets
Tracy Høeg, MD, PhD Profile picture
21 Dec 21
I'm being asked to comment on @joerogan's captivating interview of @P_McCulloughMD bc he mentioned our myocarditis study 3 times, 1 here👇. In honor of Dr McCullough saying "the truth is kryptonite" (I love that quote), I wanted to clear up a few things
🧵
1. We found that boys 12-17 w/o medical comorbidities have a risk of myo following vax #2 that exceeds their *120-day* hospitalization risk from covid even at times of high disease prevalence.
The way Dr. McCullough worded it sound like it was overall risk of hospitalization.
2. We identified 257 myocarditis cases in this age group in VAERS up through June 18th, not "thousands".
3. He was spot on about the 86% hospitalization rate
Read 8 tweets
Tracy Høeg, MD, PhD Profile picture
7 Dec 21
🇩🇪Unique, important study out of Germany:

For children without comorbidities
Chance of
Death/COVID infection
ages 5-17 = 0/7 million

Hospitalization/infection
ages 5-11 = 1/1176
ages 12-17= 1/415

ICU admission/infection
5-11 = 1/50,000
12-17=1/9091

medrxiv.org/content/10.110…
This puts into perspective why, for this demographic, vaccination needs to be incredibly safe in order to be ethical.

It is hard to understand why decisions like that of Finland (and now Norway) to wait for more safety data before recommending vaccination of 5-11 year olds who aren't high risk would be controversial

Read 6 tweets
Tracy Høeg, MD, PhD Profile picture
1 Dec 21
The highest rate of post-Pfizer vax myocarditis reported thus far: 1/2700 in 12-17 yo males after vax dose 2.
Considering covid hosp rate after dose 1 or after infection expected to be much lower than this in healthy 12-17 yos, argues against dose 2 for boys (& against mandates)
Data on (almost exclusively) Pfizer dose 1 vs dose 2 in people <30.

Essentially no difference in hospitalization rates after 1 and 2 doses; both around 90% effective

Data on previously infected having 90% lower odds of severe disease

Read 4 tweets
Tracy Høeg, MD, PhD Profile picture
23 Nov 21
Recent data from the UK's @ONS indicating those previously infected are less likely to test + for covid than those w/2 doses mRNA vax >90 days ago.
I wish they had data for hospitalizations, but this is important info we should expect from the @CDCgov ons.gov.uk/peoplepopulati…
Understanding natural immunity seems especially important for vax policy in kids given low risk of severe disease, the myocarditis risk & high percentage of people (56.2% in California, 80.36% in Arizona, for example) having previously been infected 👇
covidestim.org
Myocarditis rates in boys 12-17 post Pfizer now greater than 1/5000 in Ontario & FDA's Optum database indicates 1/5000-1/5600 for boys 12-17.(fda.gov/media/153447/d…)
Read 6 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

Like this author's thread?

Get emails when @TracyBethHoeg has new unrolls!

Check out other threads from @TracyBethHoeg!

Read all threads by @TracyBethHoeg

:(