Some thoughts from seeing a ton of Covid in the ER this week

Good news: Aside from a few patients with compromised immune systems, didn't have to hospitalize anyone who was vaxxed/boosted

Bad news: Health systems are stressed to the max

We need to adapt...quickly

Thread👇
Below I’m going to cover

1) Clinical presentations based on vax status
2) The 3 types of hospitalization: For Covid, chronic disease exacerbated by Covid, incidental Covid
3) Differences in severity/hospital needs
4) Disruptions in care Covid+ patients
5) Health system adaption
This version of Covid is crazy contagious. Our ER hit record highs in patient volumes. Hospitals everywhere over capacity during this surge of people coming in with Covid.

There is a strikingly consistent pattern based on vax status…
Boosted? Hardly saw anyone who had gotten a booster because if they caught Covid they’re likely at home doing fine or having regular cold/flu like symptoms
Vaxxed/unboosted? Tons of patients like this: wiped out, dehydrated, febrile. If they were older (eg > 55 yo or had other medical problems) often had to admit for overnight IV hydration and supportive care. But usually go home within a day or two.
Unvaxxed: These are the folks that get sick and had to be hospitalized because they need oxygen, some even younger than me. Fortunately Philly has a fairly high vaccination rate, particularly in older adults, so we’re not seeing severe cases as much as we used to.
Covid is all around. Chances are you’ll get it at some point. I share these observations in case you’re on the fence about whether you want a booster or your first shot, or if you are fully boosted, that you have some peace of mind and feel less anxious. But...
...In the meantime, a jump in vaccination rates is not going fix this insane surge in cases we're seeing right now and for the next 4-6 weeks.

Health and social systems need to seriously adapt and quickly, or our ability to provide health care will be seriously compromised...
...First, this Covid wave is different and we need to be smarter about how we interpret Covid cases that present to the ER and subsequent hospitalizations numbers (which are through the roof). They fall into three categories and can be managed differently...
1) Hospitalized for Covid: mostly unvaxxed or elderly/chronic ill & unboosted

2) Covid exacerbated a chronic illness (e.g. COPD) aka "The Covid Tip” (h/t @jeremyfaust)

3) Incidental Covid (caught on screening) happens to everybody (maybe ~1/5 of hospitalizations I saw)...
...Based on increased immunity in the population, and this lower severity strain of Covid, less people are presenting with a need for ICU level care.

But a HUGE number need supportive care over 1-3 days (e.g. IV fluids, brief oxygen support, optimization of chronic illness)...
...Second major difference in this wave is there a huge number of patients coming to the ER for testing with mild symptoms or even no symptoms because of the lack of available testing or timely outpatient evaluation capacity elsewhere...
...Lastly, the shear number of people testing positive with mild or no symptoms means there's a large population of patients with serious health needs that are having challenges accessing care because of their Covid + status...
...Dialysis patients report difficulty getting outpatient dialysis because they tested positive. Many psych crisis centers, detox units, homeless shelters, and some nursing facilities won’t accept Covid+ patients. This leads to extra time in the hospital to meet these needs...
...So what can health systems do over the next 4-6 weeks to deal with the surge?

1) Set up Covid testing and flu like illness clinics outside the ER to divert low severity patients from ERs to more convenient care and allow ERs to focus on non Covid and Covid emergency care...
...2) Optimize care pathways in the hospital. We have shown the benefits of triaging lower severity patients (who are now the majority of hospitalizations) to dedicated Covid observation units. Better care, less time in the hospital. See article below...
...Another way to do this is to post a Hospitalist physician in the ER to help manage and optimize care for patients who are waiting for an inpatient bed to open up. By the time a bed opens up 24-48 hours later, the patient may be ready to be discharged from the ER...
...3) Dialysis centers, behavioral health treatment providers, and long term care providers need to adapt to the reality that a huge proportion of patients who need their care will incidentally test positive for Covid. Decreased access to care will worsen outcomes, and...
...and with staff in these facilities almost universally vaccinated and everyone wearing masks, the risks from Covid are no worse than any other aspect of society (family gatherings, public transportation, shopping, dining, bars, etc)...
...4) Finally, implementing a low-tech text-message based monitoring program can help the millions of patients who will test positive stay safe at home and get to the hospital at the right time if they get sick. See our work below...
pennmedicine.org/news/news-rele…
......Thanks for reading. Hopefully by late Feb we will have more people boosted and access to new antivirals. Until then, things will be tough. Give us a hand in the hospital by helping to decrease the spread of Covid because right now it's unsustainable/
…PS - Fortunate to be part @Pennmedicine which has been very proactive in responding to this pandemic all along, increasing access vaccines, testing, remote monitoring and other innovations. But most of all, inspired by my colleagues. See thread below

..PS - Hospital and ER overcrowding, lack of bed capacity, and long ER waits are chronic problems made 100 times worse by Covid, omicron.

Here's the best piece explaining underlying causes and short and long term solutions:

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More from @kit_delgadoMD

8 Dec 20
>310,000 people died from gun injuries in the U.S. from 2009-17. But unlike #Covid19 stats, the total # of cases is not well established due to data gaps.

Proud of @ElinoreJKaufman who led our new paper (jamanetwork.com/journals/jamai…) that dives deep into this epidemic

THREAD👇
2/ We can get exact counts of how many deaths there are per year. Those data are available on death certificates (wonder.cdc.gov/ucd-icd10.html) collected by @CDCgov. Here’s a nice overview by @jasongoldstick @cartpatr @StrohCunningham

jamanetwork.com/journals/jamap…
3/ However, estimates of nonfatal cases have been shaky because these stats are traditionally sampled from ~100 of nation's 5,000 ERs. That sample changes year to year and there’s wide variability in ER gunshot injury volume. See @fivethirtyeight @trace:

fivethirtyeight.com/features/the-c…
Read 24 tweets
18 Aug 20
1/ Had a patient present to the ER with severe nausea and vomiting. As has become my practice, I asked "Have you struggled with pain killers, heroin, or fentanyl?" and to my surprise he answered yes. This was his first episode of severe opioid withdrawal....

cont
2/ I gave him buprenorphine and within minutes, his symptoms were relieved. Avoided labs, CT scan. Wrote him a prescription to get him through next week. Couple of weeks go by, got a message from a primary care doc colleague that he has been doing great in clinic. Made my day
3/ I've learned from asking this question regularly that there's a lot of occult opioid withdrawal out there and patients are ashamed to bring it up, but once you ask and offer a path out, they are very willing to engage. Working on making universal screening routine. stay tuned
Read 5 tweets
4 Jun 20
A friend of mine of who runs an essential, office-based business with ~50 employees and 1 employee just tested + for #COVID19 after finding out about an exposure over Memorial Day weekend family gathering

A thread on running a business in the time of #coronavirus👇
2/ The business has had a zero-tolerance policy on coming to work with any symptoms. This employee who tested positive apparently felt a little tired last week, but no fever, cough, or obvious symptoms. The employee was notified via contact tracing of the exposure on Memorial day
3/ Upon being notified of the exposure, the employee was able to get a same day #COVID19 test which turned out positive. This triggered same-day tests of everyone exposed at work and shutting down the office for deep cleaning
Read 10 tweets
31 May 20
1/ Many lawmakers are citing preventing preventing "deaths of despair" (drug use, overdose, alcoholism, suicide) as the rationale to reopen prematurely. @meganranney & @drjessigold have written a must-read piece in @statnews addressing this. A thread 👇

statnews.com/2020/05/31/dea…
2/ First, while we have ample evidence of the impact of #COVID19 (>100,000 deaths, ~4x as many hospitalizations lasting 1-2 weeks, a lasting debility among younger adults that has yet to be quantified), we don't have any data yet on deaths of despair

3/ Second, the economic conditions that lead to deaths of despair tend not to be temporary. For example,
@atheendar found that it took 5 years after factory closures to see full impact on opioid overdoses
jamanetwork.com/journals/jamai…
Read 10 tweets
28 May 20
Appreciated the opportunity to comment on 2 excellent cohort studies led by @jLewnard (Kaiser) and @leorahorwitzmd (NYU) in @bmj_latest that give us a much better understanding of who gets sick from #COVID19. A thread putting this work into perspective👇

bmj.com/content/369/bm…
2/ Take away #1: It's not just the elderly who get sick.

Most who were hospitalized for #COVID19 were *under* the age of 65:
- 53% (n=1,452) in NYU cohort
- 60% (n=1,108) in Kaiser
3/ Take away #2: Those who were hospitalized spent 1-2 weeks in hospital. A trip to the hospital is no joke.

Median length of stay (75th percentile)
- NYU cohort: 7 days (13 days)
- Kaiser cohort: 10 days (17 days)
Read 11 tweets
25 May 20
1/ The focus on #COVID19 death rates neglects the fact there are 4x as many people who spend 1-2 weeks in the hospital. True, elderly die at much higher rates, but younger adults hospitalized at high rates. Of 2,741 hospitalized:
- Most (53%) were age<65
- 437 (16%) were age<45
2/ When looking at the 990 #COVID19 patients in this cohort who developed critical illness (ICU admission, intubated on life support, death, or discharge to hospice):
- 40% were age <65
- 91 patients were 19 to 44 years old
3/ And for those who think #COVID19 poses no risk to the non-elderly population, spend a few minutes browsing some of the #COVID19 survivor group facebook pages. Ailments and debility persist for weeks. You do not want these things to happen to you:
facebook.com/groups/COVID19…
Read 6 tweets

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