>310,000 people died from gun injuries in the U.S. from 2009-17. But unlike #Covid19 stats, the total # of cases is not well established due to data gaps.

Proud of @ElinoreJKaufman who led our new paper (jamanetwork.com/journals/jamai…) that dives deep into this epidemic

THREAD👇
2/ We can get exact counts of how many deaths there are per year. Those data are available on death certificates (wonder.cdc.gov/ucd-icd10.html) collected by @CDCgov. Here’s a nice overview by @jasongoldstick @cartpatr @StrohCunningham

jamanetwork.com/journals/jamap…
3/ However, estimates of nonfatal cases have been shaky because these stats are traditionally sampled from ~100 of nation's 5,000 ERs. That sample changes year to year and there’s wide variability in ER gunshot injury volume. See @fivethirtyeight @trace:

fivethirtyeight.com/features/the-c…
4/ Why is this a problem? Because every firearm injury in the U.S. is a failure of public health, particularly accidental ones. Can't make progress if we don’t actually know case numbers, who they are happening to, etc. Nonfatal cases like this abound:
pittsburgh.cbslocal.com/2020/11/16/tod…
5/ To overcome this problem, we combined data collected from death certificates with a newer, much larger data source, the Nationwide Emergency Department Sample, which collects data from 900-1000 ERs per year (10 times the sample size), providing much more stable estimates
6/ The key findings:

From 2009-17 there was an average of 120,234 cases of firearm injuries per year, or 329 per day.

In the most recent year of data (2017), there were 138,725 cases of firearm injury. This is 380 per day, with 109 deaths and 271 people who go onto survive
7/ While suicide has been known to be the leading cause of firearm deaths, our data show once nonfatal injuries are counted, that assault injuries are the leading cause of firearm injuries (39%), followed by unintentional injuries (37%)
8/ Combining fatal and nonfatal injury counts, we now see a more complete picture of the firearm injury rates by urban vs. rural geography and by age. The hidden burden of unintentional injuries now becomes clear, particularly in rural areas and among children and young adults
9/ We find that roughly 3 out of 4 deaths occur outside the hospital, with suicide accounting for the vast majority of these cases. Of those who make it to the hospital, 93% go on to survive. Here’s some twitter only content that didn’t make it in the paper breaking this down
10/ Think about the focus on pinpointing a #COVID19 case fatality rate (CFR). Think about all we know about every type of cancer. With these data, we can now provide CFRs by firearm injury mechanism

Self-harm: 89.4%
Assault: 25.9%
Legal intervention: 23.4%
Unintentional: 1.2%
11/ This has been shown numerous times before, but there are marked racial/ethnic differences in fatalities with young Black and Latino males making up a disproportionate share of those who die in firearm assaults and middle age/older White men making up the majority of suicides
12/ Examining the data on patients who survive after emergency care, we find extremity injuries are the most common serious injury, followed by chest and abdominal. Hospitalizations last on average 4 days, with 25% lasting 9 days or more. 19% underwent major operations
13/ So while there’s a been a focus on fatalities, for every death there are twice as many survivors. However, survival comes with a substantial burden of physical and long term post-trauma stress as co-author @MarkSeamonMD and colleagues have shown

jamanetwork.com/journals/jamas…
14/ While 2017 is the most recent year of data, that seems like a lifetime ago. Our superstar lead author, trauma surgeon @ElinoreKaufman wrote this @nytimes piece on the surge in gun violence in the post #COVID19 era
nytimes.com/2020/04/01/opi…
15/ I honestly can’t remember the last time we had an ER shift without a gunshot victim. It's always been bad, but now it's worse. It's stuff like this that shakes you to the core

16/ So where do we go from here? If you are clinician, educate yourself further about what you can do. This is an excellent review article by @meganranney @EmmyBetz and colleagues (acpjournals.org/doi/10.7326/AI…) and check out these tools from @BulletPtsProj: bulletpointsproject.org
17/ You can support research and education aimed at developing and implementing public health approaches to prevent firearm injury via @ResearchAFFIRM

affirmresearch.org
18/ You can support apolitical, innovative, community and placed-based interventions proven to reduce #gunviolence such as cleaning up and greening vacant lots.

Read @EpiProfCharlie's work who has been a pioneer in this space

jamanetwork.com/journals/jamap…
19/ We can to support federal research to develop, test, and implement effective preventive interventions just like we do for any other disease. For example, see what my colleague @Rsbeidas is doing with promoting safe firearm storage among parents
pennmedicine.org/news/news-rele…
20/ Promoting safe firearm storage is of particular importance with the recent increases in gun sales. See this piece by @HoskinsKatelin and @Rsbeidas fusion.inquirer.com/opinion/commen…
21/ We can promote responsible firearm ownership by not leaving firearms unsecured in vehicles, which in turn get stolen and used in violent crimes. This has been an increasing problem npr.org/2019/05/09/717…
22/ And we can use "hot spotting" to learn from counties that have successfully reduced firearm injury deaths rates and contrast them with counties in which death rates have increased to inform prevention polices as we’re doing in our ongoing research
cceb.med.upenn.edu/WiebeGunResear…
23/ Lastly, here’s the press release on @ElinoreJKaufman's paper. You need to follow her. She’s one of the most brilliant researchers I’ve ever worked with. This is her *5th* JAMA journal paper and she’s only been on faculty for 5 months. Truly a superstar
pennmedicine.org/news/news-rele…

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More from @kit_delgadoMD

18 Aug
1/ Had a patient present to the ER with severe nausea and vomiting. As has become my practice, I asked "Have you struggled with pain killers, heroin, or fentanyl?" and to my surprise he answered yes. This was his first episode of severe opioid withdrawal....

cont
2/ I gave him buprenorphine and within minutes, his symptoms were relieved. Avoided labs, CT scan. Wrote him a prescription to get him through next week. Couple of weeks go by, got a message from a primary care doc colleague that he has been doing great in clinic. Made my day
3/ I've learned from asking this question regularly that there's a lot of occult opioid withdrawal out there and patients are ashamed to bring it up, but once you ask and offer a path out, they are very willing to engage. Working on making universal screening routine. stay tuned
Read 5 tweets
4 Jun
A friend of mine of who runs an essential, office-based business with ~50 employees and 1 employee just tested + for #COVID19 after finding out about an exposure over Memorial Day weekend family gathering

A thread on running a business in the time of #coronavirus👇
2/ The business has had a zero-tolerance policy on coming to work with any symptoms. This employee who tested positive apparently felt a little tired last week, but no fever, cough, or obvious symptoms. The employee was notified via contact tracing of the exposure on Memorial day
3/ Upon being notified of the exposure, the employee was able to get a same day #COVID19 test which turned out positive. This triggered same-day tests of everyone exposed at work and shutting down the office for deep cleaning
Read 10 tweets
31 May
1/ Many lawmakers are citing preventing preventing "deaths of despair" (drug use, overdose, alcoholism, suicide) as the rationale to reopen prematurely. @meganranney & @drjessigold have written a must-read piece in @statnews addressing this. A thread 👇

statnews.com/2020/05/31/dea…
2/ First, while we have ample evidence of the impact of #COVID19 (>100,000 deaths, ~4x as many hospitalizations lasting 1-2 weeks, a lasting debility among younger adults that has yet to be quantified), we don't have any data yet on deaths of despair

3/ Second, the economic conditions that lead to deaths of despair tend not to be temporary. For example,
@atheendar found that it took 5 years after factory closures to see full impact on opioid overdoses
jamanetwork.com/journals/jamai…
Read 10 tweets
28 May
Appreciated the opportunity to comment on 2 excellent cohort studies led by @jLewnard (Kaiser) and @leorahorwitzmd (NYU) in @bmj_latest that give us a much better understanding of who gets sick from #COVID19. A thread putting this work into perspective👇

bmj.com/content/369/bm…
2/ Take away #1: It's not just the elderly who get sick.

Most who were hospitalized for #COVID19 were *under* the age of 65:
- 53% (n=1,452) in NYU cohort
- 60% (n=1,108) in Kaiser
3/ Take away #2: Those who were hospitalized spent 1-2 weeks in hospital. A trip to the hospital is no joke.

Median length of stay (75th percentile)
- NYU cohort: 7 days (13 days)
- Kaiser cohort: 10 days (17 days)
Read 11 tweets
25 May
1/ The focus on #COVID19 death rates neglects the fact there are 4x as many people who spend 1-2 weeks in the hospital. True, elderly die at much higher rates, but younger adults hospitalized at high rates. Of 2,741 hospitalized:
- Most (53%) were age<65
- 437 (16%) were age<45
2/ When looking at the 990 #COVID19 patients in this cohort who developed critical illness (ICU admission, intubated on life support, death, or discharge to hospice):
- 40% were age <65
- 91 patients were 19 to 44 years old
3/ And for those who think #COVID19 poses no risk to the non-elderly population, spend a few minutes browsing some of the #COVID19 survivor group facebook pages. Ailments and debility persist for weeks. You do not want these things to happen to you:
facebook.com/groups/COVID19…
Read 6 tweets
5 May
(1/x) As an ER doc I have treated many patients who lost jobs due to the #CoronavirusOutbreak & they don't look like the protesters in the news
- chest pain/anxiety after losing job as a cook
- alcohol withdrawal after running out of $
- depression and suicidal thoughts

👇thread
2/ There’s ample evidence that beside the economic impact, that job and income loss leads to enormous public health impacts. For example, when auto plants shut down, there are an additional ~9 opioid overdose/100,000 people five years down the line
3/ And individual-level poverty alone is associated with an estimated 130,000 deaths per year in the U.S. More job and income loss and worsening poverty will lead to loss of health insurance and contribute to worsening mortality in the short and long term
ncbi.nlm.nih.gov/pmc/articles/P…
Read 15 tweets

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