🧵One of the great UNKNOWNS about the Omicron variant is the impact on children 4 weeks AFTER infection.
Before #Omicron 6,431 children in the U.S. were hospitalized for multi-system inflammatory syndrome (MISC) due to COVID & 55 of those kids died. Kids with MISC are SICK & require ICU care, often with blood pressure support, steroids, blood thinners, and sometimes life support
MISC is an inflammatory reaction in the body that develops about 4 weeks after infection with COVID. Each rise in COVID infection has been followed by an increase in #MISC 4 weeks later. covid.cdc.gov/covid-data-tra…
In the last month, 458 children have developed multi-system inflammatory syndrome and 3 died. The median age of patients with MIS-C was 9 years. Half of children with MIS-C were between the ages of 5 and 13 years.
Parents of unvaccinated children, should be aware of multi-system inflammatory syndrome because children may be asymptomatic during initial infection, but develop weakness, stomachache, fever or rash weeks later resulting in hospitalization.
I've posted hundreds of stories of children with MISC. This thread includes 30 children. They are difficult to read, but it's important to recognize the symptoms.
This thread includes 30 more children hospitalized for #MISC. They are difficult to read, but it's important to recognize the symptoms.
Every family with a child hospitalized for multisystem inflammatory syndrome is always unaware of MIS-C.

"If I had known and been aware of [MIS-C], I might have just gone straight to the hospital instead of to urgent care"
Thank you for helping raise awareness about multi-system inflammatory syndrome.🙏🏽
The Centers for Disease Control and Prevention, in a report published Friday, found that Pfizer’s vaccination was 91% effective at protecting adolescents against multisystem inflammatory syndrome cnbc.com/2022/01/07/cov…
Receipt of 2 doses of Pfizer-BioNTech vaccine is highly effective in preventing MIS-C in persons aged 12–18 years. These findings further reinforce the COVID-19 vaccination recommendation for eligible children. cdc.gov/mmwr/volumes/7…
Of note, the analysis focused on the 12- to 18-year age group because Pfizer vaccinations weren’t available to younger kids until November.
Be aware of the signs and symptoms of multisystem (pediatric) inflammatory syndrome #MISC #PIMS

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More from @Cleavon_MD

9 Jan
Children infected with COVID-19 are at higher risk of developing diabetes.
This article published in June 2021 discussed two NIH-supported studies confirming SARS-CoV-2 can target and impair the body’s insulin-producing cells.
Type 1 diabetes occurs when beta cells in the pancreas don’t secrete enough insulin to allow the body to metabolize food optimally after a meal. As a result of this insulin insufficiency, blood glucose levels go up, the hallmark of diabetes.
Read 9 tweets
8 Jan
13 month old Piper from Cleveland, Tennessee was co-infected with COVID-19 and rhinovirus. As a result, she developed seizures and "at one point she stopped breathing." #TheySurvivedCovid news4sanantonio.com/news/nation-wo…
After an EXPENSIVE hospitalization, consisting of several tests, including an MRI, Piper returned home on New Years Eve.
Meanwhile, at a time when the omicron variant is surging, Tennessee health officials say they will no longer provide daily COVID-19 data releases starting this week.
Read 4 tweets
8 Jan
Vaccines protect against severe illness. Data from 374 hospitalized COVID patients at Spectrum Health in Michigan. 99 patients are currently in the ICU. Of those, 90% are unvaccinated. Vaccinated = 2 dose Pfizer/Moderna or 1 dose J&J. #GetBoostedNow
Vaccinated patients with breakthrough hospitalizations are, on average, 8 years older (64 vs. 56) and have an average of 5 co-morbidities compared to 2 for unvaccinated patients.
Read 4 tweets
8 Jan
Dayton Children’s Hospital in Ohio is sounding the alarm as they’re experiencing the HIGHEST number of children hospitalized to date. dayton247now.com/news/local/you…
There are currently 24 children hospitalized with COVID-19 at Dayton Children’s -- that’s 20 more than they saw in December 2021.
“We are experiencing a surge like we've ever had. All of our children's hospitals are experiencing this same problem, which is huge numbers of pediatric patients being admitted” said Dr. Adam Mezoff, chief medical officer at Dayton Children’s Hospital.
Read 8 tweets
7 Jan
This is a reminder that a THREE-vaccine regimen is highly protective against HOSPITALIZATION, whereas high quality MASKS, such as KN95s are highly protective against INFECTION. Both are required to protect against COVID.
You can further lower your viral exposure by decreasing time spent in crowded spaces, both indoor and outdoor.
CAVEAT: The majority of COVID-19 breakthrough hospitalizations are people over the age of 65, followed by people who are immunosuppressed such as transplant recipients. These groups must remain vigilant at all times, especially during this unprecedented Omicron surge.
Read 7 tweets
6 Jan
Brandon Vaughn from Pine Knot, Kentucky is critically ill from COVID and on ECMO b/c his lungs are permanently damaged from the virus. Without a double-lung transplant he won't survive. He is 17. lex18.com/news/coronavir…
ECMO stands for extracorporeal membrane oxygenation. The ECMO machine pumps and oxygenates a patient's blood outside the body, allowing the heart and lungs to rest. It's often a bridge to lung transplant. Image
As patients awaiting lung transplantation become sicker, ECMO enables them to remain active and participating in physical therapy to prepare for the rigors of surgery
Read 9 tweets

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