1/4 Vitamin D regulates sulfate synthesis, which is required for heparan sulphate. journals.physiology.org/.../ajpendo.00…
Vitamin D hydroxylation occurs in the inner mitochondrial membrane and is NAD+ and Magnesium dependent.
2/4 Enforced/excessive GLUCOSE fuelling and hyperinsulinemia deplete cytosolic NAD+ and increase hypomagnesaemia respectively, consequently reducing cellular vitamin D hydroxylation capacity.
3/4 Lowered Vitamin D bioavailability, activation and transport capacity due to hyperinsulinaemia, negatively impacts downstream physiological processes, such as heparan sulfate synthesis and sulfurylation.
4/4 What induces obesity in mice ? (HIGH FAT WITH CARBS) !!! also decreases heparan sulphate synthesis. A common denominator for both can be explained by hyperinsulinemia. dx.doi.org/10.1136/openhr…
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1/5 Lets see how the Motor Neurone Society respond to this: Would you do me a big favour and RT ! Statins are fungal secondary metabolites which selectively inhibit (HMG-CoA) reductase, the first enzyme in cholesterol biosynthesis.
2/5 ’Secondary metabolite” is the euphemism that agenda-driven scientists & drug companies use for Statins.
Many ways to 🔽 cholesterol. Poisonous food mold toxins will do the trick if you take the risk
3/5 Prior to his departure to an end of life clinic, my dear friend (who had been prescribed 80mg Lipitor and developed MND took 80mg Lipitor to an INDEPENDENT laboratory and had the drug tested.
1/4 This is ME, I would never EVER entertain a vaccine or any other pharma drug (Statins included). I have lived my life without these drugs, and have, so far, led a very healthy life.
2/4 This is an example of how it goes horribly wrong. "Have a patient in his 50s who had an MI and CABG. The cardiologist started him on a statin. His recovery has dragged on for months. He developed malaise, memory loss, muscle pain, elevated LFTs and lowered blood counts.
3/4 He is not the man he used to be. I told him these were all recognized S/Es of statins. His cardiologist, aware of these problems, has denied they could be S/Es and cautioned him that "it would be suicide" to stop the statin. The poor guy doesn't know what to do.
1/4 2022 is getting off to a good start. About a month ago I joined a forum for people suffering from Motor Neurone Disease/ALS, and posted some information on Statins being causal in this horrible disease, since they are Mycotoxins .
2/4 I expected the usual cynical, and insulting comments, but NO. There was great interest and many people began to realise why their speech was slurred, why they experienced muscle wasting and foot drop. I then got a mail from the Administrator of the Forum, requesting
3/4 more information. She intends to do a survey to establish just how many members are using Statin drugs, and at what dosage. I mentioned that
A friend suffering from MND/ALS after using 80mg Lipitor took the drug to an INDEPENDENT lab to get the drug tested.
1/7 The acuteness of critical thinking depends on the number of causalities in one’s vocabulary and the number of precedents in one’s library.
Statins have long been pushed by pharmaceuticals and their public health lapdogs. Their rhetorical syllogism for public consumption has
2/7 been that blood cholesterol causes cardiovascular disease and Statins lower blood cholesterol without side effects and THEREFORE statins are beneficial. Some public health statinators even called for addition of statins to municipal drinking water systems.
3/7 But where is the evidence that lowering blood cholesterol decreases cardiovascular disease risk? Cholesterol is an essential element of cellular building and repair. Of course cholesterol and, eventually calcium, will collect at the sites of vascular injury—these are natural
1/4 So sad for these poor souls who still believe that ⬇️ Cholesterol = good health. “I started taking Repatha last July. I had been previously taking Lipitor. I had side effects especially muscle pain and joint pain. I had been stopped for about 5 months.
2/4 My current Cardiologist said I should try Repatha due to the low number of reported side effects. During second months injections (every two weeks) I felt mild muscle pain and weakness. I took Tylenol to help with the pain. It has become progressively more insidious.
3/4 Yesterday, 5 days from last injection I could not get out a chair, running nose, trouble walking, can't go up and down stairs, severe pain in ankles, knees, hips and back. loss of upper body strength, itching.
1/9 Chronic inflammatory diseases, such as rheumatoid arthritis, lupus, psoriasis, and infections, such as periodontal disease p.gingivalis & HIV, are associated with an increased risk of CVD. Patients with these disorders also have an increase in coronary artery calcium
2/9 measured by CT & carotid intima media thickness measured by ultrasound. WHY ?? Because inflammation & infections induce a variety of alterations in lipid metabolism that may initially DAMPEN inflammation or fight infection, but if chronic could contribute to the increased
/3
3/9 risk of atherosclerosis. The changes in lipids and lipoproteins that occur during inflammation & infection are part of the innate immune response & therefore are likely to play an important role in PROTECTING the host.
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