One of the Proximal Origin authors told @theintercept that their letter has "held up extremely well".

Really? Aside from the messy reveal of the origin of Proximal Origin, has the scientific content held up at all?
theintercept.com/2022/01/12/cov…
We know Wuhan scientists were serial passaging novel viruses in a range of cell lines.

We know they were part of a collaboration with a roadmap for inserting novel cleavage sites into novel SARS-like viruses.

We know they had direct & exclusive access to SARS2-like viruses.
We know that we have barely any insight into the viruses discovered by the Wuhan Institute of Virology after 2016.

We know that they were culturing, genetically engineering SARS-like viruses, and performing infection experiments in cells and animals at low safety BSL2 or 3.
I'd say that the scientific arguments presented in Proximal Origin have been systematically disproved over the past ~2 years.
As to the author's assertion that the paper was not written to mislead or to shut down discussion of a lab origin, they can provide us with their Feb 4 draft of Proximal Origin and their unredacted emails as proof.

Ready any time they are to look at the evidence in their hands.

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More from @Ayjchan

16 Jan
It appears that the people who convened the Proximal Origin authors who staunchly dismissed a lab #OriginOfCovid may have also shaped the membership of the @WHO team that went to China and ruled a lab origin as extremely unlikely. h/t @CDommasch
s3.documentcloud.org/documents/2079… ImageImage
@WHO @CDommasch On Feb 5, 2020, Farrar writes to NIH/NIAID leaders, asking for "names to be put forward into the [WHO #OriginOfCovid] Group from us and pressure on this group from your and our teams next week."

One of the Feb 1 call participants ended up on the WHO team.
@WHO @CDommasch It looks like they might've put forward the names of more participants on the Feb 1 call, but no others were selected. Image
Read 9 tweets
12 Jan
The questions in this letter are not specific or productive if directed at the leaders of NIH/NIAID.

The priority should be to secure a commitment from NIH/NIAID to publicly release the Feb 4, 2020 draft of Proximal Origin and the fully unredacted emails.
republicans-oversight.house.gov/wp-content/upl…
None of the 7 questions ask specifically what the perceived competing interests in the Feb 1 group are, ie, what the impact of a lab #OriginOfCovid would be on the participants' careers and reputations; why several contributors went completely unacknowledged in Proximal Origin.
None of the 7 questions ask specifically what corrective actions should be taken while this issue is being resolved, eg, editor's note on Proximal Origin, recusal of Feb 1 participants from all academic/advisory activities relating to #OriginOfCovid
Read 15 tweets
12 Jan
I'm all ears to hear about the precise scientific process that occurred between Feb 2 and Feb 4, 2020 where top experts in virology and evolutionary biology completely changed their minds about the likelihood of SARS-CoV-2 emerging from a lab.
In Jeremy Farrar's book, he noted that Marion Koopmans had said furin cleavage site insertions happen in viruses all the time naturally.

Kristian Andersen, lead author of Proximal Origin, said just because it happened in nature did not rule out unnatural origins.
By the time Proximal Origin was published (i.e., the final paper), Koopmans argument had been absorbed into the manuscript without acknowledgement.

"insertions.. can occur.. the polybasic cleavage site can arise by a natural evolutionary process."
nature.com/articles/s4159…
Read 8 tweets
11 Jan
Transcripts of the early 2020 exchanges on the #OriginOfCovid among leading scientists in the US & Europe show they were privately worried about a lab origin of Covid-19.

Yet, publicly they authored Proximal Origin, which dismissed lab origin hypotheses.
republicans-oversight.house.gov/wp-content/upl…
In private, they understood that "the only people with sufficient information or access to samples to address [the #OriginOfCovid] would be the teams working in Wuhan."

In public, they wrote "we do not believe that any type of laboratory-based scenario is plausible."
The day (Feb 4, 2020) that a first draft of Proximal Origin was shared with Fauci and Collins by Farrar, Farrar said Edward Holmes (one of the Proximal Origin authors) had guessed 60:40 lab and Farrar guessed 50:50.
Read 23 tweets
11 Jan
Peter Daszak asked for US-funded virus data to be withheld, FOIAed by @USRightToKnow

"It's extremely important that we don't have these sequences as part of our PREDICT release.. Having them as part of PREDICT will being very unwelcome attention"
usrtk.org/wp-content/upl…
@USRightToKnow Only way to know if some of these virus sequences are completely new and still not public is for NCBI database or PREDICT to release the data.
@USRightToKnow The FOIA process is so protracted that we're only seeing April 2020 emails in Jan 2022. And there are many, many more FOIAs and appeals against redactions still ongoing for emails from 2020.

See the longer list of FOIAs by the @USRightToKnow here:
usrtk.org/biohazards-blo…
Read 5 tweets
8 Jan
Stories of Covid-19 whistleblower doctors, journalists & scientists - disappeared, imprisoned, penalized, maltreated, slandered as rumormongers - doesn't inspire confidence that the world will get a timely alert the next time a mysterious outbreak appears.
cnn.com/interactive/20…
These reports are old, but the problem persists.

How can global pandemic response be rapid if there are countries where alerting your hospital colleagues to a novel outbreak and telling them to wear protective equipment results in punishment?
theguardian.com/world/2020/mar…
I don't think it is a misstatement to say doctors were being brutally silenced when they blew the whistle on the earliest Covid-19 cases. Several lost their lives in this process after being forced to sign confessions and returning to fight the outbreak.
Read 4 tweets

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