Dr Dan Goyal Profile picture
Jan 25 21 tweets 5 min read
How similar is Covid to Flu in the UK?

On an individual level, the risk of severe Covid-19 in a fully boosted adult is significantly lower with Omicron than Delta.

How close is that individual risk to the risk with Flu?

Short 🧵
I will provide some data and sources at the end, but the main points are:
1. Rate of death from Covid has dropped significantly over the last year. By about ten-fold.
2. Omicron may even be less than this, once we are out of the Omicron wave.
3. Overall risk is still likely more than X 6 higher than Flu.

But all this does depend on what you see as flu!
When people talk of flu and Covid, most want the reassurance that Covid will be less dangerous and less dominant. “Flu is awful but rarely bad, unless frail”
Under this perception of the flu, Covid really is quite different. And even If Omicron-levels of severity remain, Covid is - sorry - much more severe than Flu.
Direct deaths from Flu are really uncommon. That is, someone gets flu so severe that they have to go to hospital. You have likely only heard of a handful of people ever being admitted to hospital with flu.
In this, the public perception of flu, Covid-19 caused around 120 times more deaths than Flu in 2020. And about the same in 2021.

Comparing Covid to a bad flu year, it is about X 30 deaths.
But this does include pre-vaccine deaths. Total Covid mortality so far is about 230 per 100k. Since vaccinations it has fallen recently to around 60 per 100k. Flu is typically around 5-10 per 100k (but this likely includes contributory deaths).

apps.who.int/iris/rest/bits…
In terms of individual risk, it is slightly different. Firstly, we don’t know how many flu cases there are worldwide and therefore what the infection fatality rate (IFR) is. We have estimates. On WHO estimates IFR is about 0.05%. who.int/influenza/Glob…
What we don’t know is whether this Omicron surge of cases and deaths will be it for the year. If so, Covid is killing > X 6 that of flu. A new variant together with immune waning together with reduced booster uptake…it is likely to be higher.
Under this same perception of flu (the “public” perception), there is the ‘flu-deaths are in the frail and extremely vulnerable’ experience. And yes, some approaching the end of their life do succumb to flu.

This is not Covid!
Covid increases every adults chance of dying by the same proportion (assuming vaccine status is the same and access to healthcare remains). Indeed, the % of excess deaths in those under 65yrs remains higher than older age groups, still!
And finally, complications of Covid versus Flu.

Flu can cause bacterial pneumonia, heart problems and post-viral syndromes.

Covid causes much more! Especially if needing hospital treatment. Risks of many major disorders, including stroke, heart attacks, lung disease,… all ⬆️
Severe Covid causes a slightly higher complication rate as being admitted with bacterial pneumonia. But there is clear evidence of milder disease causing complications too.
Flu is a serious disease causing a heavy toll on life and on healthcare provision.

Bacterial pneumonia is much more deadly and much more burdensome than flu (although some are triggered by flu - the hidden cost of flu!).
Covid is still causing more death than pneumonia, way more than flu, and carries a massive burden on the health system. The secondary effects of Covid are almost unquantifiable.,,
ONS have recommended an investigation into home deaths from non-Covid conditions as evidence suggests this may be due to a failing health systems.
From my perspective, we rarely see serious Flu cases, and very rarely see younger (<70yrs) with complicated flu. We see a lot of pneumonia and now a lot of Covid.

Individual risk is a lot less for most.

But I think at best we are looking at doubling the burden from Pneumonia.
Is Covid the same as flu? No. It is its own entity and something we have never experienced before. We should define it as such.

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More from @danielgoyal

Jan 25
Some policy makers are using the “Flu” comparison to argue for doing less/nothing to control Covid.

Here I present an argument against such policies.

Understanding the risk of Covid is useful when deciding your own opinion about gov policy.

🧵

[FYI ⬇️ - Flu vs Covid]
Disclaimer: not a statistician. Clinical academic. This is my understanding of the current risks told plainly. Others better placed to comment further: @Kit_Yates_Maths @chrischirp @dgurdasani1 @JamesWard73 @jburnmurdoch @EricTopol @DrEricDing and others…
Risk to self: the actual risk of death from Omicron is less (vs Delta).

In crude terms, the risk of death from Flu is 0.05% (prob much less).

The current risk from Covid seems to be ~0.2% (vaccinated, confirm, ave)

This is a direct comparison. Real risk is very different.
Read 9 tweets
Jan 22
Despite the dramatic title, Mr Snowdon raises an important point: what happens when number-crunchers neglect human factors.

I fear though, Mr Snowdon has succumbed to the very criticism he levy’s against those arguing for stronger mitigations

Thread
This is not a criticism of the many astute and invaluable statisticians. More a challenge to basic assumptions.

Indeed, often the distance and objectivity is appreciated.
But It is a pattern that seems to be emerging from economists and statisticians, that somehow the resistance of the PM to further mitigations was in some way a success.

While the economic argument seems absent, focus on healthcare numbers seems popular and problematic.
Read 19 tweets
Jan 16
Oh my, Johnson must be getting desperate. His tactic for holding onto power now seems to be “talking up” his success in managing the pandemic.

Some things to bear in mind as the battle for the narrative continues…
While we can get distracted by the ‘with’ or ‘from’ Covid argument, here is the excess death data…one of the good overall measures for how a nation responded to the pandemic.

Ireland, Germany and France had about half as many excess deaths as the UK.
We averaged between 500 to 1000 extra deaths at home per week, throughout the pandemic.

Note, only a fraction were Covid.
Read 11 tweets
Jan 14
Covid update from the UK frontline.

Things are looking different at the “front door”

Here’s how…
Context:
▪️Scotland
▪️Non-city
▪️High vax rate + high booster rate
▪️Respectful people: masks, distancing, isolating when needed.
▪️Care homes still protected
I compare this wave with the last delta wave July ‘21 to Nov ‘21 - so called, Delta baseline.

Just my experience of the patients I see.

Our rates have been about 3 X higher than our delta baseline.
Read 11 tweets
Jan 10
Back on the frontline the damage caused by 'letting it rip' is all too apparent. "Broken" seems to be the word of the day - both for staff and NHS.
As the battle for the Omicron narrative begins, hearing the word 'coping' now stings a bit too much...'success' a swell of anger...
Lots of Covid today. New outpatient treatments (someone has to administer them); loads of patients not well, but with some effort can be managed at home; the inpatients, and the odd escalation to Level 2 care..
It's a lot of work in the middle of our usual brutal winter caseloads
Being on the senior medical team is tough. Lots of compromising, and spreading too little way too thinly. Sleepless nights and little left to give for the family. I feel for the patients more...although many don't realise. I feel also for the juniors and med students...
Read 8 tweets
Jan 9
How will the pandemic end?

To appreciate the magnitude of lunacy behind the UK, US, and some other nations pandemic strategy, it is helpful to try and “game out” how the pandemic will “end”.

Here are some scenarios…
1. Waves of new variants with increasing immune tolerance to SARS-CoV-2.

Only someone very brave or very foolish would bet against more variants. As the population develops immunity to one variant the conditions become favourable for another to take hold.
We don’t know what such variants may look like. They may be more severe or less severe, they may cause more illness in the young or less, they may be more responsive to vaccines or less. No doubt, on this path uncertainty remains high.
Read 18 tweets

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