1. Some background information on the much discussed recent research paper about the potentially deadly NeoCoV and its close relative, PDF-2180-CoV
Close relatives of MERS-CoV in bats use ACE2 as their functional receptors
biorxiv.org/content/10.110…
Close relatives of MERS-CoV in bats use ACE2 as their functional receptors
biorxiv.org/content/10.110…
3. To start, I consider anal swabbing of bats sacrilegious behaviour only fit for heathens and bat guano should be used only for its allotted purposes ;) 
4. Also a dangerous paper as it gives ideas for immoral scientists to create extremely deadly pathogens with one simple mutation, not a good idea, is it?
and now all easily done by downloading sequences via Genbank and modern lab techniques.
and now all easily done by downloading sequences via Genbank and modern lab techniques.
5. BSL Level?
I saw a lot of pseudo virus work & it says:
Q.X, L.C, C.B.M, C.L, J.Y.S, P.L, & F.T. performed the experiments
6 work at State Key Laboratory of Virology, Institute for Vaccine Research & Modern Virology Research Center, College of Life Sciences, Wuhan University
I saw a lot of pseudo virus work & it says:
Q.X, L.C, C.B.M, C.L, J.Y.S, P.L, & F.T. performed the experiments
6 work at State Key Laboratory of Virology, Institute for Vaccine Research & Modern Virology Research Center, College of Life Sciences, Wuhan University
6. BSL 3?
According to their now deleted website:
web.archive.org/web/2021032122…
The Wuhan University researchers use "a Biological Safety Level 3 Laboratory, Biological Safety Level 3 Animal Laboratory, and Biological Safety Level 4 Laboratory (In construction)."
According to their now deleted website:
web.archive.org/web/2021032122…
The Wuhan University researchers use "a Biological Safety Level 3 Laboratory, Biological Safety Level 3 Animal Laboratory, and Biological Safety Level 4 Laboratory (In construction)."
7. In my research report:
researchgate.net/publication/35…
There is more information on their labs and many biosafety issues identified (sections 2, 3 and 4), but that's mainly about their ABSL3 Lab and Bat researchers who failed to use PPE on sampling expeditions.
researchgate.net/publication/35…
There is more information on their labs and many biosafety issues identified (sections 2, 3 and 4), but that's mainly about their ABSL3 Lab and Bat researchers who failed to use PPE on sampling expeditions.
8. BSL3?
In this paper:
ncbi.nlm.nih.gov/labs/pmc/artic…
"All SARS-CoV-2 authentic virus-related experiments (S01321010A) were approved by Biosafety Committee Level 3 (ABSL-3) of Wuhan University, Wuhan Institute of Virology & Hubei Provincial CDC"
In this paper:
ncbi.nlm.nih.gov/labs/pmc/artic…
"All SARS-CoV-2 authentic virus-related experiments (S01321010A) were approved by Biosafety Committee Level 3 (ABSL-3) of Wuhan University, Wuhan Institute of Virology & Hubei Provincial CDC"
9. and here a similar statement:
nature.com/articles/s4155…
"All SARS-CoV-2 live virus-related experiments were approved by the Level 3 Biosafety Committee (ABSL-3) of Wuhan University. All experiments involving SARS-CoV-2 were performed in the BSL-3 facility"
nature.com/articles/s4155…
"All SARS-CoV-2 live virus-related experiments were approved by the Level 3 Biosafety Committee (ABSL-3) of Wuhan University. All experiments involving SARS-CoV-2 were performed in the BSL-3 facility"
10. and here, same:
animal-evolution.whu.edu.cn/ace2_bioRxiv2.…
"All SARS-CoV-2 live virus related experiments were approved by the Biosafety Committee Level 3 (ABSL-3) of Wuhan University.
All experiments involving SARS-CoV-2 were performed in the BSL-3 facility. SARS-CoV-2"
animal-evolution.whu.edu.cn/ace2_bioRxiv2.…
"All SARS-CoV-2 live virus related experiments were approved by the Biosafety Committee Level 3 (ABSL-3) of Wuhan University.
All experiments involving SARS-CoV-2 were performed in the BSL-3 facility. SARS-CoV-2"
11. Ke Lan
I did notice that one of the authors "Dr. Ke Lan" (involved in all papers listed including the latest Neo Cov one) was an early reader of my reports on Researchgate which surprised me at the time, so he has been on my "watch list" since 2020.
mri.whu.edu.cn/info/1094/2490…
I did notice that one of the authors "Dr. Ke Lan" (involved in all papers listed including the latest Neo Cov one) was an early reader of my reports on Researchgate which surprised me at the time, so he has been on my "watch list" since 2020.
mri.whu.edu.cn/info/1094/2490…
12. Dr. Ke Lan (2)
He is the Director of the State Key Laboratory of Virology, Wuhan University
His orcid profile:
orcid.org/0000-0002-0384…
His Lab on Researchgate:
researchgate.net/lab/Ke-Lan-Lab
He is the Director of the State Key Laboratory of Virology, Wuhan University
His orcid profile:
orcid.org/0000-0002-0384…
His Lab on Researchgate:
researchgate.net/lab/Ke-Lan-Lab
13. WHU ABSL3
"in fact, the Chinese NHC designated WU ABSL-3 as China’s lab for implementation of the International Convention on Prohibition of Development, Production, Storage of Biological & Viral Weapons & Destruction of Such Weapons"
researchgate.net/publication/35… (Page 6)
"in fact, the Chinese NHC designated WU ABSL-3 as China’s lab for implementation of the International Convention on Prohibition of Development, Production, Storage of Biological & Viral Weapons & Destruction of Such Weapons"
researchgate.net/publication/35… (Page 6)
14. Wuhan University Research
"we analyze the extraordinary biological characteristics of bats & scientific research value"
"Diversity & evolution of bat immune genes & evolution of virus receptors in bats are directions we focus on in the near future"
animal-evolution.whu.edu.cn/research.htm
"we analyze the extraordinary biological characteristics of bats & scientific research value"
"Diversity & evolution of bat immune genes & evolution of virus receptors in bats are directions we focus on in the near future"
animal-evolution.whu.edu.cn/research.htm
15. School of Life Sciences, WHU
They are here talking about Zhao Huabin, Vice Dean, Animal Diversity and Molecular Evolution Mechanism, Laboratory Location: Room 5119
animal-evolution.whu.edu.cn/info/1002/1204…
animal-evolution.whu.edu.cn/info/1005/1125…
Their publications are listed here:
animal-evolution.whu.edu.cn/publications.h…
They are here talking about Zhao Huabin, Vice Dean, Animal Diversity and Molecular Evolution Mechanism, Laboratory Location: Room 5119
animal-evolution.whu.edu.cn/info/1002/1204…
animal-evolution.whu.edu.cn/info/1005/1125…
Their publications are listed here:
animal-evolution.whu.edu.cn/publications.h…
16. More background on Wuhan University's Labs
Thread 1:
Thread 1:
https://twitter.com/BillyBostickson/status/1435143896489607172
17. More background on Wuhan University's Labs
Thread 2:
Thread 2:
https://twitter.com/BillyBostickson/status/1267797253260861441
18. Background on Wuhan University' Bat Research
Thread 3:
Thread 3:
https://twitter.com/BillyBostickson/status/1342706721068732416
21. Lei Cao (not Wuhan)
Only one co-author of the "Neo Cov" paper, L.C (Lei Cao) was from CAS Key Laboratory of Infection & Immunity, National Laboratory of Macromolecules, Institute of Biophysics, CAS, Beijing.
english.ibp.cas.cn/research_23463…
Only one co-author of the "Neo Cov" paper, L.C (Lei Cao) was from CAS Key Laboratory of Infection & Immunity, National Laboratory of Macromolecules, Institute of Biophysics, CAS, Beijing.
english.ibp.cas.cn/research_23463…
22. Lei Cao (2)
Research profile:
orcid.org/0000-0003-4289…
He co-authored this paper with authors from State Key Laboratory of Pathogen & Biosecurity (Academy of Military Science)
Characterization & structural basis of a lethal mouse-adapted SARS-CoV-2
europepmc.org/article/PMC/84…
Research profile:
orcid.org/0000-0003-4289…
He co-authored this paper with authors from State Key Laboratory of Pathogen & Biosecurity (Academy of Military Science)
Characterization & structural basis of a lethal mouse-adapted SARS-CoV-2
europepmc.org/article/PMC/84…
23. "Neo-Cov" Conclusion?
Virologist, Leave them bat's asses alone!
Last thing we need is a new lab leak of a mutated pathogen with a 30% death rate, as Bill Gallaher warned about last year (MERS + SARS-COV-2 recombination)
and
Virologist, Leave them bat's asses alone!
Last thing we need is a new lab leak of a mutated pathogen with a 30% death rate, as Bill Gallaher warned about last year (MERS + SARS-COV-2 recombination)
https://twitter.com/BillyBostickson/status/1279154412854763520
and
https://twitter.com/BillyBostickson/status/1279358247594455042
unroll "Neo-Cov" paper co-author's investigation @threadreaderapp
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