Graham Pechenik Profile picture
Feb 2 6 tweets 5 min read
All your vapes are belong to us?

New patent granted—“Delivery System for Ayahuasca-Like Substances”

Claims DMT vapes, 5-MeO-DMT vapes, & 2C-B vapes

These claims can be immediately enforced

1/6
The patent claims:

“A device for the delivery of a substance comprising:

a chamber comprising at least one vaporizable formulation wherein the vaporizable formulation comprises the substance and wherein the substance comprises one or more of”

DMT, 5-MeO-DMT, or 2C-B

2/6
The application was first filed as a provisional in July 2020

Did DMT vape pens exist in the prior art before the priority date?

This @doubleblindmag article was first published on Feb. 5, 2020:

3/6
doubleblindmag.com/are-dmt-vape-p…
The patent examiner made a single prior art rejection, over a PCT application filed by Syqe Medical—“Personal vaporizing device”

patents.google.com/patent/WO20171…

Applicant argued that Syqe Medical did not describe a vape containing DMT, 5-MeO-DMT, or 2C-B

The claims were allowed

4/6
So—DMT vape pens have now been patented

(But, despite their applications as written about by @shayla__love, not by Philip Morris)

It was by a patent attorney, prosecuting an application with himself as the sole inventor

A PCT is also pending

Will this patent be enforced?

5/6
Patent: patft.uspto.gov/netacgi/nph-Pa…

Prosecution: patentcenter.uspto.gov/#!/application…

Follow psychedelic patents with the @PsilocybinAlpha Patent Trackers:

psilocybinalpha.com/data

6/6

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More from @calyxlaw

Dec 31, 2021
Patentable pharmahuasca “kits of parts”?

New PCT app published: “Compositions & Kits of Parts Comprising N,N-DMT & Harmine & Their Use in Therapy”

“An alternative to ayahuasca that solves the problems of side effects…is pharmahuasca, also known as synthetic ayahuasca”

1/4
Applicant is University of Zürich, w inventors Dario Dornbierer, Davor Kosanic, & Milan Scheidegger

All are founders at Reconnect Labs: “a Spin-off of the University of Zürich…setting standards for a novel kind of ethical drug development company”

reconnect-foundation.org/reconnect-labs/

2/4
The PCT app claims:

–a “kit of parts” of DMT & harmine

–a composition of DMT & harmine

-their use to treat psychiatric disorders

None were found inventive

3/4
Read 4 tweets
Dec 30, 2021
New psychedelic inventions?

∰ Field Trip—tryptamine prodrugs

∰ Greenway DNA—personalized psychedelic treatment

∰ Small Pharma—deuterated DMT

1/9
Field Trip $FTRP: “Tryptamine Prodrugs”

Application covers diacid hemiester prodrugs of tryptamines & isotryptamines, eg, psilocin, 4-HO-DET, 4-HO-DiPT, & 4-HO-MiPT

Head twitch response & pharmacokinetics in rats & humans with 4-hemiglutarate & 4-hemisuccinate of 4-HO-DiPT

2/9
Is Field Trip $FTRP FT-104 a prodrug of 4-HO-DiPT?

In “Use in Treatment,” app discloses intramuscular & subcutaneous injection or oral tablet administration of:

N,N-isopropyltryptamine-4-glutarate (4-hemiglutarate of 4-HO-DiPT)

& subcutaneous “injectable formulation kit”

3/9
Read 9 tweets
Dec 29, 2021
New psychedelic inventions?

⁂ Phil Wolfson/KRF—ketamine for postpartum symptoms

⁂ Psilo Scientific—psychoactive & psychedelic fungus extraction

⁂ Cognigenics—5-HT2A “cognitive upgrade”

⁂ Liechti—MDMA response prediction

⁂ Small Pharma—DMT-type compound synthesis

1/14
…and more new psychedelic inventions?

⁂ Ixtlan—psilocybin for Alzheimer’s

⁂ Spirify—hydroxynorketamine analogs

⁂ Guangzhou Dazhou Biomedicine—transdermal ketamine

⁂ Disruption Labs—nanoparticle compositions

⁂ Daniel Lilly—“medicinal food products” with psilocybin

2/14
Ketamine Research Foundation (KRF)—“Ketamine for the Treatment of Postpartum Symptoms & Disorder”

First inventor Phil Wolfson

“treatment of all forms of emotional and psychological symptoms and disorders related to childbirth and its aftermath”

patentscope.wipo.int/search/en/deta…

3/14
Read 14 tweets
Nov 20, 2021
Novel ketamine + psilocybin inventions?

New patent applications published:

𝔎 Celon Pharma—pulmonary administration of ketamine

𝔎 Univ Kansas—ketamine treatment for ALS

𝔎 Takeda Pharm—depression tx, after ketamine therapy

𝔎 CaaMTech—combinations of serotonergic drugs

1/6
Celon Pharma—“Ketamine Composition for Use in a Method of Treatment of Depression by Pulmonary Administration”

–inhalable dry powder ketamine compositions

–dosage regimens for their use “in a cycle of administrations of sequences of single doses”

appft.uspto.gov/netacgi/nph-Pa…

2/6
University of Kansas—“Ketamine Treatment for Amyotrophic Lateral Sclerosis”

Covers use of ketamine to:

–extend life expectancy

–increase number of days of survival

–reduce rate of deterioration of body weight

Claims all found novel & inventive

patentscope.wipo.int/search/en/deta…

3/6
Read 6 tweets
Nov 18, 2021
Ibogaine + MDA = “an extremely beneficial drug”?

#TBT to 1968 patents by Claudio Naranjo

“The medical preparation of the invention produces most unexpected and beneficial results, by for example alleviating fears and anxieties which may have been present in the patient”

1/12 Image
The patents claimed medical preparations of:

(1) ibogaine, iboga alkaloid extract, or total extract; plus

(2) amphetamine, MDA, TMA, tetrahydronapthylamine, or naphazoline

“The best results have been obtained with” MDA

The combination “forms an excellent medicine"

2/12 ImageImage
The ibogaine “has the effect of considerably clarifying the mind of the sick person, giving him a kind of extra-lucid vision of his ‘ego.’ It likewise excites the memory centre of the brain thus revealing memories which may go back to a period before the age of 4…”

3/12 Image
Read 12 tweets
Mar 21, 2021
New Compass Pathways patents granted?

Another US patent was granted on March 16, 2021

This is Compass’ second US patent, in same family as the first patent granted on December 31, 2019

New ‘257 patent: patft.uspto.gov/netacgi/nph-Pa…

First ‘175 patent: patft.uspto.gov/netacgi/nph-Pa…

1/7
A primary difference between the new ‘257 & the first ‘175 patent is:

– ‘175 patent claims methods “of treating drug resistant depression” by orally administering “an oral dosage form“ of the COMP360 psilocybin Polymorph A

– ‘257 patent claims the “oral dosage form” itself

2/7
Just as with the first ‘175 patent, the new ‘257 patent claims the psilocybin Polymorph A by reference to its “XRPD diffractogram”

These are the peaks displayed when the polymorph is analyzed by X-ray

Compass unsuccessfully sought claims without these XRPD limitations

3/7
Read 7 tweets

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