COVID-19 can cause lasting damage to the cardiovascular system, even in “mild” cases that didn’t require hospitalisation during the acute phase of infection.
A new study shows we’re going to see more heart disease, strokes, blood clots & other problems.🧵 nature.com/articles/s4159…
The authors have a warning for governments letting the virus spread:
“Governments and health systems around the world should be prepared to deal with the likely significant contribution of the COVID-19 pandemic to a rise in the burden of cardiovascular diseases.” (Continued 👇.)
“Because of the chronic nature of these conditions, they will likely have long-lasting consequences for patients and health systems and also have broad implications on economic productivity and life expectancy.”
Apart from lost quality of life, COVID-19 is going to be expensive!
The authors are quite clear about the need to keep COVID-19 cases low.
They write that “the best way to prevent Long COVID and its myriad complications, including the risk of serious cardiovascular sequelae, is to prevent SARS-CoV-2 infection in the first place.”
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I suspect a single-dose booster won’t be enough against the omicron strain, because it’s changed so much it’s almost like a new virus. One dose wasn’t enough against the original strain, either. Two doses seems more realistic.
Our best bet for bringing the pandemic to a end may be nasal spray vaccines.
Early experiments suggest these may be more resistant to variants and do a much better job of preventing infection and blocking transmission than the current generation of vaccines.
But vaccines alone aren’t going to end the pandemic.
Vaccination is extremely important but we also need to make some changes to the way we live our lives. Hopefully many of these changes can be unobtrusive, such as improving ventilation & using HEPA technology to clean the air.
Masks should be encouraged for primary school students, and the Government should consider supplying schools and parents with comfortable, high-quality KF94 masks.
Concerning new UK data show protection against hospitalisation is greatly reduced for the omicron variant. About 6 months after 2 doses, effectiveness is reduced to 52%.
The good news is that a third vaccine dose brings protection against hospitalisation up to 88% for the omicron variant.
Protection against hospitalisation caused by the delta variant remains at a very high level, for both two and three doses.
A study from South Africa recently estimated that two doses of the Pfizer-BNT vaccine offers 93% protection against hospitalisation caused by the delta variant, and 70% for the omicron variant. nejm.org/doi/full/10.10…
The omicron variant is AT LEAST as bad as the 2020 virus.
But the omicron variant is far more transmissible, and our vaccines don’t work as well against it.
This means that an omicron variant epidemic will infect far more people than a delta variant epidemic would.
In practical terms, this means the omicron variant is MORE dangerous than the delta variant.
I modelled what would happen if either of these variants were allowed to spread in Western Australia with only a *double-dose* vaccination level of 90% (i.e., hardly any third doses).
I recently went to two Christmas parties. Not a single person was wearing a mask.
And it was okay, because there’s no epidemic where I live. Western Australia has managed to sustain zero COVID for nearly 2 years.
Eliminating COVID-19 was always possible. The world chose not to.
This got people talking. Good. But the point isn’t Christmas parties or Western Australia. It’s that elimination is the only long-term strategy for ending the pandemic. I’m not someone who typically praises China, but the government there understood this. bmj.com/content/375/bm…
But elimination doesn’t require draconian measures. There are many tools in the toolbox that we’re not yet using (or not using widely), such as ensuring everyone has a better mask. People need masks that can block aerosols. Better ventilation is also key. masks4all.co/faqs-on-better…
People vaccinated with 2 doses of the Pfizer-BNT vaccine likely have no protection against infection with the omicron strain. Protection after 3 doses has likely taken a big hit as well.
Antibodies collected from people vaccinated with 2 doses of the Pfizer-BNT vaccine fare poorly against the omicron variant, although vaccinated people with a previous infection fared better.