In case anyone is keeping score, we applied comparative evolutionary approaches (long before reinfection was common) to predict the durability of immunity, and our predictions were SPOT ON.
's comparative evolutionary analysis predicted an 18% probability of reinfection at ~270 days; David Bean and @ManishSagar_MD's subsequent empirical finding was 18% reinfection by 275–300 days after primary infection.
's comparative evolutionary analysis predicted a 34% probability of reinfection at ~450 days; Sumit Malhotra et al.'s subsequent empirical finding was 34% reinfection by 420–480 days after primary infection.
is pleased to communicate an answer to what has often been called one of the greatest unknown factors regarding #COVID19: the durability of immunity upon natural infection.
A @Nature video listed the durability of immunity upon natural infection as one of four questions regarding COVID-19 (1): “This is a big question, and immunologists are working feverishly to determine what immunity to SARS-CoV-2 could look like.”
.@statnews listed the durability of immunity upon natural infection a most pressing question regarding COVID-19 (2): “People seem to be protected from reinfection,” wrote @DrewQJoseph, @HelenBranswell, and @cooney_liz, “but for how long?”