BERBERINE
Lewis rats were immunized with porcine cardiac myosin to induce experimental AUTOIMMUNE MYOCARDITIS,TREATED WITH BERBERIN nd specific JAK inhibitor
BERBERIN and AG490 significantly reduced impaired cardiac function and pathophysiological severity
HOW MUCH ENDOCYTOSIS AND CD147 CONTRIBUTE
in comparison to ace2
"still of opinion that endocytosis is a equal or significant route of entry to coV2.
majority of population use some drugs to downregulate ace2. despite of this,magnitude of covid is awesome"
#akcomicron
OMICRON-- DIFFERENT MODE OF CELL ENTRY
more cell types infected
"uses an endosomal pathway for entry that increases number of cell types it can infect. This switch of entry pathway could explain increase in transmissibility of Omicron variant" news-medical.net/news/20220109/…
COMMON ANTI-PARASITIC AGENT EASES MOTOR SYMPTOMS, AIDS REMYELINATION IN MS MOUSE MODEL
IVM in autoimmune disease
"ivermectin eased clinical manifestations of experimental autoimmun encephalomyelitis (EAE;an induced autoimmune disease similar to MS in human multiplesclerosisnewstoday.com/2018/07/13/ant…
POOR AB RESPONSE TO VACS OR NATURAL COV2 INFECTION
*pts on immunosuppressive drugs
*immunocompromised due to diseases like HIV
*neoplastic blood disorders, leukemia, lymphoma
*hereditary dysfunctions of T and B cells
"According to Public Health England (PHE),information about Lambda Variant Covid Symptoms is given below.According to PHE,no patient of this variant has had fatal disease so far.PHE reports that lambda version causes any major ill-effects" mpnrc.org/lambda-variant…
PLEASE
*i have kept an eye on fatalities occurred, despite of taking proper HCQ prophylaxis in 2020
PROUDLY SAYING, NONE
*in covid 2021, we need a fine tune in dosage and protocols, in older ones.but i assure everybody listening,
DRUGS ARE STILL GOLDSTANDARD
please watch updates
*drugs are working good in new strains too, but virus is looking slightly faster than drugs
*usual one drug regime used in older strain, getting insufficient, specially in younger population
1/1
@Psychoman53 1/2
*in youngsters, increased dosage/number of drugs, are needed to control progression of disease, and still more aggressive efforts are needed to combate hypoxia
@Psychoman53 1/3
*THIS EXTRA ORDINARY SUSCEPTIBILITY OF YOUNGER PEOPLE, LOOKS TO BE RELATED TO THEIR HEIGHTENED ANDROGENIC RECEPTORS/EXPRESSIONS, YOUNGER GIRLS ARE LOOKING LESS AFFECTED. this suggests a more aggressive use of anti-androgens in youngsters