This is an intriguing Q. A few hypotheses 1. Vax'd young healthy college kids have succumb to fear-mongering & have irrational worry about own breakthrough 2. This cognitive bias more common on Left, where most youth are... 1/5
3. Any student who protests is called ableist, eugenicist or white supremacist. Hyperbolic use of these terms is chilling for speech and demeans what these terms actually mean.
4. The culture of wanting to take retribution against someone for one little thing they said has reached an apogee, students want to take no risks.
No forgiveness and can poison job opportunities
5. Universities aren't doing as good a job in teaching analytical thinking skills as they used to.
6. Other ideas...?
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NEW Paper 2022! @vkprasadlab
Once again we analyze the use (& MISUSE) of the parachute analogy in biomedicine
This time we trace citations to the original BMJ 2004 paper & the Yeh remix!
Let me walk you through the paper..
[THREAD]
First, you need to know that a parachute has a huge effect size. Without one, falling from plane, u are sure but dead. With one, deaths are ~1 per 10 million jumps.
Effect size, ARR = 99.999....
AKA amazing. Such a huge effect size, you don't need any trial to know it works!
Second, know that many in medicine love to believe they have something just as good.
My chemotherapy drug -- it's a parachute
A cloth mask to prevent covid -- a parachute
The Impella or Aortic balloon pump - two parachutes
renal artery stenting - parachute
Dazzling, daring, stunning piece by JH Russell and @DmpPatterson in @tabletmag tellin the true story of masking during COVID 👇
"The overselling of policies began in the early days of the pandemic with the problematic #masks4all movement...."
must read
🧵 tabletmag.com/sections/scien…
First, they are spot on. Many don't see it, but Trump is so influential, He sets the sides!
When he was for schools, Liberals lost their mind and worked to keep them closed; AAP did a bizarre flip flop & sided with unions to keep them closed.
And the same for masks 👇
Absolutely right again 👇
Inexperienced & naive twitter pundits kept saying the pandemic would vanish if we all worse a mask or n95 for 14, 21 days, a claim....
Wow! 👇
secondary endpoint
potential for infinite looks at data
yet still, scant events (50?) of dubious clinical value (some asx?)
Plus other issues, including durability discussed in video
But postponing/ flip flopping is going to poison vax confidence
White house should not have pressured FDA on boosters
Gruber and Kraus should still be there
Politics cannot dictate vaccine approval
This is a total fiasco
This administration is doing serious, serious damage to vaccine confidence
The backlash will hurt a lot of people
States will get rid of good programs to encourage routine childhood immunization
Vaccines become even more political
This administration does not have a plan here
They should have awknowledged natural immunity
and tried for just 1 dose in people with no prior NI
Lots of talk of wearing masks.
The policy question is: what happens when you advise people to:
Wear cloth masks
Wear surgical
Wear n95s
You have to combine mask properties with real world compliance
Ans:
No benefit
11% benefit in setting w no immunity & high bias rct
No trial
The 11% benefit should have an* because there is a serious risk of concealment being revealed in the study due to imbalance and study population by arm
If you pair this imbalance with the idea that people will be slightly less likely to report symptoms if they were enrolled on the margin. You have a big problem