Eric Topol Profile picture
May 1 4 tweets 3 min read
The uptake of smartwatches in the US is as fast as mobile phones in the 1990s
economist.com/technology-qua…
In @TheEconomist new Technology Quarterly on health and medical apps, and how wearable sensors are changing #healthcare and medical research economist.com/technology-qua… by @SlaveaChankova
A contemporary assessment of sensors and #AI algorithms for a broad range of use cases including individualized nutrition, pandemic surveillance, disease management and digital therapeutics
This graphic from the report doesn't make wearing sensors look enjoyable ;-)

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More from @EricTopol

Apr 29
So much for the pandemic being over
latimes.com/california/sto… @LukeMMoney @ronlin Image
From March 2021 Image
We decided..... Image
Read 4 tweets
Apr 24
You know it's an usual moment in the pandemic when New Zealand leads the world in cases per capita, And is on the descent from its Omicron wave
@OurWorldInData newsnodes.com/worldmonitor/
New Zealand with a total of 674 deaths for the entire pandemic, chance of dying approximately 1 in 7800, compared with the US, approaching 1 million confirmed deaths, 1 in 333 (24-fold)
A highly Unusual moment (anything but usual).
Sorry for my typo.
Read 4 tweets
Apr 13
🆕@NEJM on 4th dose vaccine
Compared with 3-doses (controls), >180,000 matched pairs, age 60+: significant increased protection from death, hospitalization, severe disease, symptomatic infection thru 30d
nejm.org/doi/full/10.10…
@OriMagen1 @RanBalicer @ClalitResearch @ClalitHealth
Vaccine effectiveness 4-shots vs 3-shots
Vs Omicron:
Hospitalization 72%
Death 76%
These are compelling data for a 2nd booster vs severe outcomes in people age 60+ who are >4 months from 3rd shot, backed up by other recent reports. Duration likely for another 4 months. But frequent boosters is only temporizing, an unsustainable long-term strategy ......
Read 6 tweets
Apr 9
The US pandemic: We know what a country-wide surge looks like (wave 5). It's clear now that wave 6 (BA.2), yet still in the works, will not resemble that
All regions of the US are well past 50% (dominant) BA.2 by sequencing/2
There's a lot of cross-immunity between BA.1 (monster wave) and BA.2. ~50% of Americans were infected in < 10 weeks.
No sign of increase of hospitalizations (actually a sustained decrease) /3
Read 5 tweets
Apr 5
Just published @NEJM
4th dose vaccine protection in >620,000 people vs 3-doses in >620,000, all age 60+, Omicron wave, Israel
—4-fold lower rate of severe disease, no waning at 6 weeks
—2-fold lower rate of infection, rapidly waned
nejm.org/doi/full/10.10…
The relative and absolute benefit of the 4th dose (in Omicron wave) is substantially less than the 3rd (Delta wave) vs severe illness
3rd dose report nejm.org/doi/full/10.10…
Relative: nearly 20-fold (3rd dose) vs 4-fold (4th dose)
Absolute: 7.5 vs 3.9 cases/100,000 person-days
—The 4th dose works vs severe disease but the challenge is Omicron, which has considerable immune escape, vastly different from the original strain.
—Until now, from this report, the data were only at 12+ days (extended to 6 weeks)
—There's another major study of people age 60+👇
Read 5 tweets
Mar 31
The protective benefit of Prior Covid ("natural immunity") in 2 large studies just out, prior to Omicron, and added impact of vaccination @TheLancetInfDis
Sweden thelancet.com/journals/lanin…
Brazil
thelancet.com/journals/lanin…
Two very different conclusions
My synthesis of the data, including the Omicron wave, and long overdue recognition for infection-induced immunity
theguardian.com/commentisfree/…
Read 4 tweets

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