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Dr Elisa Perego Profile picture
@elisaperego78
May 16, 2022 • 16 tweets • 8 min read • Read on X
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I'm a bit exhausted to repeat this. But #LongCovid | covid are among the best studied diseases in history. In addition to the sheer amount of studies, a lot of research has been done with some of the most advanced techniques in biomedical research. Let's have a look!

🧵
Brightest X-rays on Earth expose covid damage to the lung | the innovative imaging technique can pick up micrometre-scale of organs

@Nature | November 2021

nature.com/articles/d4158…
In @NatGeo | January 2022 | a long but accessible read on the implementation of cutting-edge technology and scanning techniques to explore the vascular nature of covid

nationalgeographic.com/science/articl…
Another cutting-edge scanning technique, polarized Xenon MRI, has revealed long-term damage to the lung after SARS-CoV-2 infection

#LongCovid

sheffield.ac.uk/news/study-con…
Shotgun total sequencing DNA analysis of stools from covid patients, weeks after onset => perturbations of gut microbiome composition, linked to disease severity

Alterations connected with inflammation markers in bloodwork

#LongCovid

@bmj_latest

gut.bmj.com/content/70/4/6…
Abnormalities in the oral microbiome have been identified in #LongCovid patients, potentially linked to an abnormal immune response and a pro-inflammatory status following SARS-CoV-2 infection

umassmed.edu/news/news-arch…
Blood DNA methylation and outcomes in COVID-19

…lepigeneticsjournal.biomedcentral.com/articles/10.11…
The role of mass spectrometry in defining different covid phenotypes (sub-types) and other key clinical challenges in the pandemic

frontiersin.org/articles/10.33…
The application of mass spectrometry reveals a prolonged inflammatory status in #LongCovid

pubmed.ncbi.nlm.nih.gov/33391730/
Gene expression changes in acute covid may have an impact on the development of #LongCovid

news-medical.net/news/20211006/…
This is just a short thread to show how some of the most innovative techniques available on earth have already been applied to covid and #LongCovid since 2020 and 2021. Surely, further research can be developed! Not all available studies will be perfect or leading to treatment
However, even this brief review shows that claims that covid and #LongCovid are "mysterious" entities are unfounded. There is a lot of research going on. We need to translate research into treatment. But the knowledge is being built right now.
People, especially those with a degree in medicine, or those employed in academic or research positions, should really work on reading the publications in their own field before speaking about #LongCovid as "rare" or "mysterious". Alternatively, they can simply avoid the topic!
I add here another 🧵 I have been compiling with many publications on #LongCovid including cardiovascular disease, and many other effects in multiple organs. I hope it's useful to keep up with growing data on the disease

And I add here another 🧵 on cardiovascular disease and complications in #LongCovid
With a lot of publications and case studies

And I add here another 🧵 on #LongCovidKids the long term effects of SARS-CoV-2 infection on children. There are many publications on this topic too. Long Covid in children is also increasingly documented and studied

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More from @elisaperego78

Dr Elisa Perego Profile picture
Jan 20
"I was still ok 10 min before the match"

There are concerns over a possible gastrointestinal virus spreading at the top Australian Open in elite tennis. Star Flavio Cobolli suffered a shocker early defeat, while being debilitated by sudden symptoms.

ilgiornale.it/news/tennis/vi…
Another player apparently affected is Luciano Darderi, who still managed to win his match, as he started to feel really unwell only towards the end. His GI symptoms were reportedly aggravated by medication he had to take for some injury.
World number 22 Cobolli admitted he was so ill he would have withdrawn, had the tournament been less prestigious. He started to feel unwell just before or at the beginning of his match, which he lost in the end.
Read 6 tweets
Dr Elisa Perego Profile picture
Oct 27, 2025
"No further delay should be acceptable."

Proud to co-author this #LongCovid declaration to demand urgent action to fully recognise, treat and prevent Long Covid

with @LCawarenessInt @winslow_la @TogetherWeMask @longcovidaragon @TheWHN
@COVID19persist1

longcovidriseup.eu/lc-declaration/
"Long COVID is a new complex chronic condition caused by SARS-CoV-2. Born in 2020 from the lived experience of patients, the term broke the early myth that COVID-19 was either a brief mild illness or a rapidly fatal disease."
"[the term #LongCovid] sparked a global grassroots movement demanding recognition and research. Long COVID is a vascular, chronic multisystemic condition caused by a virus that challenges medicine and public health in unprecedented ways."
Read 20 tweets
Dr Elisa Perego Profile picture
Sep 26, 2025
SARS-CoV-2 infection is a significant risk for cardiovascular health. Cardiovascular sequelae and manifestations are a key facet of #LongCovid. Patients deserve care
A thread with research studies

#CovidHeart
#LongCOVIDHeart
#LongCovidAwareness #LaRAGEauCoeur
@winslow_la
Cardiovascular disease as part of Long COVID: a systematic review

academic.oup.com/eurjpc/article…
Cardiovascular outcomes in long COVID-19: a systematic review and meta-analysis

frontiersin.org/journals/cardi…
Read 17 tweets
Dr Elisa Perego Profile picture
Jul 23, 2025
There are concerns about a "mysterious illness" going through the pelaton at the top cycling event Tour de France. Several racers were reported to be affected already days ago. Since then, star M. van der Poel has withdrawn with pneumonia while R. Evenepoel left feeling "empty" Image
One of the most prominent racers affected by the "mysterious illness" was superstar and current Tour leader Tadej Pogačar, who lamented cold symptoms but remains in the race. Van der Poel also had cold symptoms, which has now progressed to pneumonia

rmcsport.bfmtv.com/cyclisme/tour-…
Tadej Pogačar told reporters on Sunday "Am I sick? Thanks for checking in, actually I'm better, it's almost over" He added: "I have a bit of a runny nose, a bit of a cough, but I'm not really sick. It's just a bit of a pain in the *ss."
Pogačar currently remains Tour leader
Read 7 tweets
Dr Elisa Perego Profile picture
May 20, 2025
Five years ago today the term #LongCovid was first used as a Twitter hashtag. A single tweet by a patient linked together a growing, grassroots movement of people who weren't recovering from Covid. Across the world, we were fighting for recognition and studying our own disease Image
Image
Image
I feel strange posting this again after five years of fighting, suffering, and a global, grassroot mobilization of Covid survivors, who changed how Covid was understood and communicated to the public
Far from being a short, respiratory illness in most, dangerous only for the "old and frail", as said in early guidelines, Covid was a prolonged, multi-system disease, which could be severe and even fatal also in the "young and healthy": #LongCovid

sciencedirect.com/science/articl…
Read 20 tweets
Dr Elisa Perego Profile picture
May 19, 2025
A severe surge in Covid cases is reported in Asian countries.
"In Hong Kong, weekly cases surged over 30 times in 10 weeks. Cases also surged by nearly 30 per cent in a week in Singapore. There are also reports of significant surges in China and Thailand"
indiatoday.in/diu/story/in-n…
There also seems to be a raise in certain indicators about Covid in Italy, such as child hospitalizations, in Italy, where novel variants of concern have been detected
However, surveillance in the country remains low

Italy PM Giorgia Meloni would be suffering from a "fever" and has cancelled institutional meetings

Read 4 tweets

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