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Dr Elisa Perego Profile picture
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May 18 • 5 tweets • 3 min read
Happy to see a good discussion of #LongCovid in Italy's primetime TV news @tg5med | not perfect, but excellent to see the cardiovascular and cardiopulmonary sequelae openly mentioned, among others | including footage of scanners Image
There has been sometimes a poor depiction of #LongCovid in some Italian venues (with a focus on "fatigue" etc. but not the most severe organ damage, which we know it's not rare even in young people with "mild" disease at onset). The news could have been more explicit about this
But it's still a step forward in respect to less explicit information, provided by some television venues in various occasions (TG5 itself wrongly mentioned #LongCovid lasted only 3 months a few days ago!)
Mentioned the post covid clinic at the Gemelli Hospital in Rome | of particular interest @MartaEsperti @LongCovidItalia @celeste_sabato
@surf4children

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More from @elisaperego78

Dr Elisa Perego Profile picture
May 20
The UK Health Security Agency has "upgraded" Omicron BA.4 and BA.5 to Variants of Concern. The European ECDC did the same on 12 May.
BA.4 and BA.5 display enhanced immune evasion, which could impact "on the epidemiological situation in the EU/EEA" (ECDC).

news.sky.com/story/covid-19…
On the enhanced immune escape capacity of a subset of omicron sub-lineages, including BA.4 and BA.5

see e.g. [preprint]

biorxiv.org/content/10.110…
An easy to read report on research on BA.4 and BA.5. Note that immunity provided by BA.1 infection against these new sub-lineages appear to be quite poor, with particular regard to unvaccinated individuals

news-medical.net/news/20220503/…
Read 5 tweets
Dr Elisa Perego Profile picture
May 20
We know, scientifically, that #LongCovid is a complex, multi-system, multidimensional disease. It can affect, basically, all organs and body systems. There are thousands of publications on Long Covid and around half a million on covid in general. Children are affected, too.

🧵
#LongCovid can present with a wide range of manifestations, including severe, life threatening. This is not surprising: it's the same for acute covid, and it's well documented in the scientific literature. We know that many, including pediatric patients, have been ill since 2020.
I have not followed the interview in question. But any medical professional, or researcher, who deny the huge amount of scientific evidence available on #LongCovid should not be involved in managing patients, research, consultancy, or advising governments and health bodies.
Read 6 tweets
Dr Elisa Perego Profile picture
May 20
The WHO is convening an emergency meeting over the #monkeypox outbreak, now basically reported across all continents. About Europe, note that the draft genome just published was taken from a skin lesion swab in Portugal on *4 May*. The disease has been here for a while already
This is the 1st draft genome sequence for the 2022 multi-country outbreak. The information notes 4 May as the day of sample collection from the skin lesions of a male patient in Portugal. ~20 cases were confirmed in the country as of 19 May

virological.org/t/first-draft-…
The incubation period of monkeypox is given as variable in the WHO timesheet. The brodear range is reported at 5 to 21 days. The average range is at 6 to 13 days. After symptom onset, the disease has a "prodromal" | early phase with flu-like symptoms

who.int/news-room/fact…
Read 9 tweets
Dr Elisa Perego Profile picture
May 19
My solidarity to all healthcare professionals, including nurses, who contracted covid at work and are now living with #LongCovid. It is of paramount importance healthcare professionals, as well as other people living with Long Covid, are fully supported
As we have just passed #NursesDay it is important to consider how much talent and expertise can be lost, if optimal care and support pathways aren't implemented by providers and employers. Healthcare professionals are among the most hit by #LongCovid
The loss of healthcare expertise to #LongCovid is a huge hit for providers and new patients alike. Healthcare systems are under severe duress in this pandemic.
And, as usual, my solidarity to all sufferers beyond age, gender, and profession
Read 4 tweets
Dr Elisa Perego Profile picture
May 19
Ok not exactly breaking news. We have known since 2020 thanks to the patient community that #LongCovid can come after a "mild" or even asymptomatic infection. Many people with Long Covid were never hospitalized in the acute phase

🧵
However, I think it's important to be clear here: many people who were never hospitalized in the acute phase *did* experience what I would define as severe disease. First, we know people with severe symptoms in hotspots were left at home because of healthcare collapse
Second, severity in acute covid was initially defined by guidelines as based on the severity of respiratory symptoms, the gravity of covid pneumonia, and the likelihood to develop ARDS, respiratory failure and organ failure. But covid is much more than a respiratory illness
Read 4 tweets
Dr Elisa Perego Profile picture
May 19
Ok someone said it before me! What about Long Monkeypox. Didn't know if it was in good taste to talk about it so soon. But we learnt the hard way to consider morbidity, not only mortality

Anyway, #monkeypox has known long-term health effects and complications as per @WHO

🧵
Reported complications of historical cases of #monkeypox | i.e. before current cases | include secondary infections, bronchpneumonia, sespis, encephalitis, and infection of the cornea, with resulting loss of vision

who.int/news-room/fact….
Asymptomatic (subclinical | "silent") infection is also noted to occur. #monkeypox as a symptomatic disease can be prolonged in itself, with symptoms and signs reported to last for 2 to 4 weeks according to official guidelines | a bit of deja vu here with the early covid reports!
Read 7 tweets

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