4/ Finally, in severe cases you can get a meningoencephalitis. This can cause edema/T2 signal in the deep gray structures, cortex, and white matter. There can also be leptomeningeal enhancement. Lumbar puncture with CSF analysis can help in diagnosis.
1/Having trouble remembering what you should look for in vascular dementia on imaging?
Almost everyone worked up for dementia has infarcts. Which ones are important?
Here’s a thread on the key findings in vascular dementia!
2/Vascular cognitive impairment, or its most serious form, vascular dementia, used to be called multi-infarct dementia.
It was thought dementia directly resulted from brain volume loss from infarcts, w/the thought that 50-100cc of infarcted related volume loss caused dementia
3/But that’s now outdated. We now know vascular dementia results from diverse pathologies that all share a common vascular origin.
It’s possible to lose little volume from infarct & still result in dementia.
So if infarcts are common—which contribute to vascular dementia?