Lea Alhilali, MD Profile picture
May 23, 2022 4 tweets 4 min read Read on X
1/
Monkey pox! It’s everywhere, at least in the news.

Here’s a 🧵about the neuroimaging manifestations of monkey pox

#MonkeypoxVirus #monkeypox #neurorad #FOAMed #NeuroTwitter #MedTwitter #RadRes #FOAMrad #neurology

pubmed.ncbi.nlm.nih.gov/15499541/ Image
2/
The most common manifestation on neuroimaging is tonsillar enlargement & cervical lymphadenopathy

It starts in submandibular nodes w/faucial tonsil enlargement. It progresses to lower lymph node stations & axillary nodes

These images are in primates journals.asm.org/doi/10.1128/JV… Image
3/
These are very hot on FDG PET. There are not reports of necrotic lymph nodes, but data is scarce

academic.oup.com/jid/article/20… Image
4/
Finally, in severe cases you can get a meningoencephalitis. This can cause edema/T2 signal in the deep gray structures, cortex, and white matter. There can also be leptomeningeal enhancement. Lumbar puncture with CSF analysis can help in diagnosis.

pubmed.ncbi.nlm.nih.gov/15499541/ Image

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Oct 17
1/My hardest thread yet! Are you up for the challenge?

How stroke perfusion imaging works!

Ever wonder why it’s Tmax & not Tmin?

Do you not question & let RAPID read the perfusion for you? Not anymore! Image
2/Perfusion imaging is based on one principle: When you inject CT or MR intravenous contrast, the contrast flows w/blood & so contrast can be a surrogate marker for blood.

This is key, b/c we can track contrast—it changes CT density or MR signal so we can see where it goes. Image
3/So if we can track how contrast gets to the tissue (by changes in CT density or MR signal), then we can approximate how BLOOD is getting to the tissue.

And how much blood is getting to the tissue is what perfusion imaging is all about. Image
Read 18 tweets
Oct 15
1/”That’s a ninja turtle looking at me!” I exclaimed. My fellow rolled his eyes at me, “Why do I feel I’m going to see this a thread on this soon…”

He was right! A thread about one of my favorite imaging findings & pathology behind it Image
2/Now the ninja turtle isn’t an actual sign—yet!

But I am hoping to make it go viral as one. To understand what this ninja turtle is, you have to know the anatomy.

I have always thought the medulla looks like a 3 leaf clover in this region.

The most medial bump of the clover is the medullary pyramid (motor fibers).

Next to it is the inferior olivary nucleus (ION), & finally, the last largest leaf is the inferior cerebellar peduncle.

Now you can see that the ninja turtle eyes correspond to the ION.Image
3/But why are IONs large & bright in our ninja turtle?

This is hypertrophic olivary degeneration.

It is how ION degenerates when input to it is disrupted. Input to ION comes from a circuit called the triangle of Guillain & Mollaret—which sounds like a fine French wine label! Image
Read 9 tweets
Oct 13
1/Time to FESS up! Do you understand functional endoscopic sinus surgery (FESS)?

If you read sinus CTs, you better know what the surgeon is doing or you won’t know what you’re doing!

Here’s a thread to make sure you always make the important findings! Image
2/The first step is to insert the endoscope into the nasal cavity.

The first two structures encountered are the nasal septum and the inferior turbinate. Image
3/So on every sinus CT you read, the first question is whether there is enough room to insert the scope.

Will it go in smoothly or will it be a tight fit? Image
Read 19 tweets
Oct 10
1/I always say you can tell a bad read on a spine MR if it doesn’t talk about lateral recesses.

What will I think when I see your read? Do you rate lateral recess stenosis?

Here’s a thread on lateral recess anatomy & a grading system for lateral recess stenosis Image
2/First anatomy.

Thecal sac is like a highway, carrying the nerve roots down the lumbar spine.

Lateral recess is part of the lateral lumbar canal, which is essentially the exit for spinal nerve roots to get off the thecal sac highway & head out into the rest of the body Image
3/Exits have 3 main parts.

First is the deceleration lane, where the car slows down as it starts the process of exiting.

Then there is the off ramp itself, and this leads into the service road which takes the car to the roads that it needs to get to its destination Image
Read 21 tweets
Oct 8
1/Remembering spinal fracture classifications is back breaking work!

A thread to review the scoring system for thoracic & lumbar fractures—“TLICS” to the cool kids! Image
2/TLICS scores a fx on (1) morphology & (2) posterior ligamentous complex injury

Let's start w/morphology

TLICS scores severity like the steps to make & eat a pizza:

Mild compression (kneading), strong compression (rolling), rotation (tossing), & distraction (tearing in) Image
3/At the most mild, w/only mild axial loading, you get the simplest fx, a compression fx—like a simple long bone fx--worth 1 pt.

This is like when you just start to kneading the dough. There's pressure, but not as much as with a rolling pin! Image
Read 13 tweets
Oct 6
1/Does PTERYGOPALATINE FOSSA anatomy feel as confusing as its spelling?

Does it seem to have as many openings as letters in its name?

Are you pterrified of the pterygopalatine fossa (PPF)?

Let this thread on PPF anatomy help you out. Image
2/The PPF is a crossroads between the skullbase & the extracranial head and neck

There are 4 main regions that meet here:

(1) Skullbase itself posteriorly, (2) nasal cavity medially, (3) infratemporal fossa laterally, and (4) orbit anteriorly. Image
3/At its most basic, you can think of the PPF as a room with 4 doors opening to each of these regions: one posteriorly to the skullbase, one medially to the nasal cavity, one laterally to the infratemporal fossa, and one anteriorly to the orbit Image
Read 18 tweets

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