2/Older pt w/lower extremity numbness. MRI showed intradural, extra-axial rounded lesions in the lower thoracic region that avidly enhanced on post-contrast imaging—like gang busters enhancement
3/On the T2 weighted images, the lesions showed a very distinct donut-like appearance, with a very dark, almost black rim and a bright center.
4/On contrast imaging, the donuts were connected as twisty, tubular structures—my fellow said they looked like crinkle fries! (and yes, I know McDonald’s doesn’t serve crinkle fries as illustrated, but it’s just an illustration—there aren’t fries in the spine either 😉)
5/Tubular sounds like a vessel! And these did empty out into the neural foramina. But the spinal angio was negative for a vascular lesion (not all images shown—normal studies don’t make for good twitter images)
6/These are intradural varices! B/c of slow flow, they may not fill on angiography & lose their flow void centrally—causing a“donut sign.” Etiology is unclear, but likely acquired
So the next time you see donuts & fries in the spine—you can be sure you've got the right diagnosis
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Brain MRI anatomy is best understood in terms of both form & function.
Here’s a short thread to help you to remember important functional brain anatomy--so you truly can clinically correlate!
2/Let’s start at the top. At the vertex is the superior frontal gyrus. This is easy to remember, bc it’s at the top—and being at the top is superior. It’s like the superior king at the top of the vertex.
3/It is also easy to recognize on imaging. It looks like a big thumb pointing straight up out of the brain. I always look for that thumbs up when I am looking for the superior frontal gyrus (SFG)
If the patient is symptomatic & the greatest stenosis from the plaque is >70% of the diameter of normal distal lumen, patient will likely benefit from carotid endarterectomy
But that doesn’t mean the remaining patients are just fine!
3/Yes, carotid plaques resulting in high-grade stenosis are high risk
But assuming that stenosis is the only mechanism by which a carotid plaque is high risk is like assuming that the only way to kill someone is by strangulation.
1/My hardest thread yet! Are you up for the challenge?
How stroke perfusion imaging works!
Ever wonder why it’s Tmax & not Tmin?
Do you not question & let RAPID read the perfusion for you? Not anymore!
2/Perfusion imaging is based on one principle: When you inject CT or MR intravenous contrast, the contrast flows w/blood & so contrast can be a surrogate marker for blood.
This is key, b/c we can track contrast—it changes CT density or MR signal so we can see where it goes.
3/So if we can track how contrast gets to the tissue (by changes in CT density or MR signal), then we can approximate how BLOOD is getting to the tissue.
And how much blood is getting to the tissue is what perfusion imaging is all about.