Enrique de-Madaria Profile picture
Jun 26 β€’ 29 tweets β€’ 12 min read
Quick introduction to autoimmune pancreatitis, based on my recent talk in the @EurPancClub meeting #EPCKyiv2022 #GItwitter #TheAmylaseSchool #PancreasTwitter #PancreasLovers #MedTwitter
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Epidemiology
Presentation
Extrapancreatic involvement (type 1 autoimmune pancreatitis)
AIP and IBD I
AIP and IBD II
Pathology AIP type 1-I
Pathology AIP type 1-II
Pathology AIP type 1-III
Pathology AIP type 1-IV
Pathology AIP type 2-I
Pathology AIP type 2-II
Biomarkers
Imaging of autoimmune pancreatitis
Imaging II- type 1 autoimmune pancreatitis extrapancreatic involvement
Imaging III- type 1 autoimmune pancreatitis extrapancreatic involvement
Imaging VI- type 1 autoimmune pancreatitis extrapancreatic involvement
Classification of bile duct involvement, type 1 autoimmune pancreatitis
Mikulicz disease, type 1 AIP
Retroperitoneal fibrosis, type 1 autoimmune pancreatitis
Diagnosis of autoimmune pancreatitis, not easy!!
Diagnosis of AIP II
Diagnosis of mass-forming autoimmune pancreatitis, BE CAREFUL!!! Cancer is more frequent
Treatment of autoimmune pancreatitis

@maloehr1
Treatment of autoimmune pancreatitis, follow-up and relapses
Rituximab on autoimmune pancreatitis
I hope you learned and liked it! If so please retweet the first tweet to share it!
By the way, please join the @harvardmed MINIMALLY INVASIVE AND NOVEL THERAPEUTICS (MINT) 2022 course on foregut diseases, for GI, surgeons, nurses... interested in foregut diseases
Have a look and join now in advances.massgeneral.org/digestive-heal…

@krishnanendo @CharuParanjape @MGHSurgery

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More from @DeMadaria

Apr 11, 2021
How to do a pro search in Pubmed?

This special #TheAmylaseSchool infographics (or mini-course) is a guide to navigate the deep waters of Pubmed (and not get drown). I provide a pdf at the end of the Twitter Thread

1/5
Author Journal Date Title Abstract Language Affiliation
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How to search in Pubmed 2/5
Mesh terms, Boolean operators, My NCBI filters
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How to search in Pubmed 3/5
How to save your search
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Read 15 tweets
Feb 21, 2021
What is a Groove Pancreatitis (GP)? #GroovePancreatitis #ParaduodenalPancreatitis #CysticDystrophyDuodenalWall What are the symptoms, consequences, management?
Do not miss this @aegastro #HiloAEG #UEGambassador @my_ueg Twitter thread #TheAmylaseSchool Image
The groove area or pancreaticoduodenal groove involves the space between the duodenum, the head of the pancreas and the common bile duct karger.com/Article/FullTe… Image
Groove pancreatitis is a segmental chronic pancreatitis that affects the groove area; it was described in 1973 by Becker
link.springer.com/book/10.1007/9… Image
Read 15 tweets
Jan 3, 2021
Cross-sectional imaging often reveals unexpected pancreatic cystic lesions, it is a frequent clinical problem, Should we observe or remove it? What's the diagnosis? Is our patient in danger of malignancy?
Don’t miss this @aegastro @my_ueg #EducAEG #UEGambassador twitter thread
Importance of Pancreatic Cystic Neoplasms (PCN):
Most are asymptomatic at diagnosis, frequency increases with age
Symptoms: acute pancreatitis (Wirsung obstructed by the cyst or mucus), pain, obstructive chronic pancreatitis, jaundice
> symptoms, >malignancy risk!
Classification of PCN:
Mucinous: intraductal papillary mucinous neop. and mucinous cystic neop.
Nonmucinous: serous cystic neoplasm, solid pseudopapillary neoplasm and cystic neuroendocrine tumours
Endoderm- derived columnar epithelium is characteristic for mucinous lesions
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Read 18 tweets
Apr 26, 2020
LetΒ΄s talk about #PancreasHistory! The discovery of Insulin, Banting, Best, McLeod & Collip, the first patient who received insulin for #Diabetes Mellitus #UEGambassador @my_ueg @ESEndrocrinology @YouppiePancreas @EurPancClub @ChahalPrabhleen @PerelmansPearls #gigang
For ancient physicians the most important feature of diabetes was the increased urine output. Diabetes was a term for polyuria derived from the classical Greek word "diabainein" meaning to walk with the legs apart, later diabetes "a passer through" or a "siphon".
The Greek physician Arateus (credited for the term Diabetes) described it as "the melting down of flesh and limbs into urine"
Read 26 tweets
Jul 8, 2019
Pancreatic exocrine insufficiency: causes, consequences, diagnosis and treatment.

DonΒ΄t miss this @my_ueg #UEGambassador twitter thread

#PancreasHGUA @aegastro @AESPANC @EurPancClub @pancreatology @hpb_so @me4_so #SoMe4Surgery @GVAsanitat @GVAsalualicante @isabial_iis Image
Pancreatic juice is composed by
- Acinar secretion, rich in enzymes
- Ductal secretion: A) Water that will help to flush the acinar secretion B) Bicarbonate that will neutralize gastric acid in the duodenum; some enzymes like lipase do not work in an acid environment ImageImage
The arrival of acid and protein products to the duodenum induce S-cells to produce secretin which stimulates ductal secretion. Fatty acids, amino-acids and vagus nerve induce I-cells to produce cholecystokinin (CCK) which stimulates acinar secretion Image
Read 23 tweets

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