By the way, please join the @harvardmed MINIMALLY INVASIVE AND NOVEL THERAPEUTICS (MINT) 2022 course on foregut diseases, for GI, surgeons, nurses... interested in foregut diseases
Have a look and join now in advances.massgeneral.org/digestive-healβ¦
This special #TheAmylaseSchool infographics (or mini-course) is a guide to navigate the deep waters of Pubmed (and not get drown). I provide a pdf at the end of the Twitter Thread
1/5 Author Journal Date Title Abstract Language Affiliation
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How to search in Pubmed 2/5
Mesh terms, Boolean operators, My NCBI filters
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How to search in Pubmed 3/5
How to save your search
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The groove area or pancreaticoduodenal groove involves the space between the duodenum, the head of the pancreas and the common bile duct karger.com/Article/FullTeβ¦
Groove pancreatitis is a segmental chronic pancreatitis that affects the groove area; it was described in 1973 by Becker link.springer.com/book/10.1007/9β¦
Cross-sectional imaging often reveals unexpected pancreatic cystic lesions, it is a frequent clinical problem, Should we observe or remove it? What's the diagnosis? Is our patient in danger of malignancy?
Donβt miss this @aegastro@my_ueg#EducAEG#UEGambassador twitter thread
Importance of Pancreatic Cystic Neoplasms (PCN):
Most are asymptomatic at diagnosis, frequency increases with age
Symptoms: acute pancreatitis (Wirsung obstructed by the cyst or mucus), pain, obstructive chronic pancreatitis, jaundice
> symptoms, >malignancy risk!
Classification of PCN:
Mucinous: intraductal papillary mucinous neop. and mucinous cystic neop.
Nonmucinous: serous cystic neoplasm, solid pseudopapillary neoplasm and cystic neuroendocrine tumours
Endoderm- derived columnar epithelium is characteristic for mucinous lesions
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For ancient physicians the most important feature of diabetes was the increased urine output. Diabetes was a term for polyuria derived from the classical Greek word "diabainein" meaning to walk with the legs apart, later diabetes "a passer through" or a "siphon".
The Greek physician Arateus (credited for the term Diabetes) described it as "the melting down of flesh and limbs into urine"
Pancreatic juice is composed by
- Acinar secretion, rich in enzymes
- Ductal secretion: A) Water that will help to flush the acinar secretion B) Bicarbonate that will neutralize gastric acid in the duodenum; some enzymes like lipase do not work in an acid environment
The arrival of acid and protein products to the duodenum induce S-cells to produce secretin which stimulates ductal secretion. Fatty acids, amino-acids and vagus nerve induce I-cells to produce cholecystokinin (CCK) which stimulates acinar secretion