Sometimes pancreatitis involves the duodenum, let´s talk about paraduodenal/groove pancreatitis
Don't miss this #GItwitter thread based on my talk for @harvardmed @HMSPostgradCE #HarvardMINT2022 course
Thanks, @CharuParanjape @krishnanendo for one of my best experiences ever! Pancreas inflammation involving the duodenum has many names: Cystic dystrophy on aberrant pancreas of the duodenal wall, Groove pancreatitis... Adsay and Zamboni proposed paraduodenal pancreatitis as a term that involves these 2 organs

Our dream comes true: the #WATERFALLtrial has been published in @NEJM Aggressive fluid resuscitation in acute pancreatitis is not safe & does not improve outcomes #GItwitter #SomosAEG @aegastro
What's behind this publication?
It all started 21 years ago
nejm.org/doi/full/10.10… 2001, I started to attend patients with acute pancreatitis as a GI resident in @GVAsalualicante. Books and papers recommended aggressive fluid resuscitation. It was believed that many fluids increased pancreatic blood flow preventing pancreatic necrosis

1/5 @pancreatitis_nl trials addressing the management of infected pancreatic necrosis in acute pancreatitis #TheAmylaseSchool @my_ueg @EurPancClub @MarcBesselink #ClinicalResearch 2/5
Panther trial: A Step-up Approach or Open Necrosectomy for Necrotizing Pancreatitis @NEJM
This trial robustly demonstrated that minimally invasive treatment (percutaneous drainage and minim. invasive surgery if needed) was better than open surgery
nejm.org/doi/10.1056/NE…

Quick introduction to autoimmune pancreatitis, based on my recent talk in the @EurPancClub meeting #EPCKyiv2022 #GItwitter #TheAmylaseSchool #PancreasTwitter #PancreasLovers #MedTwitter
👇👇👇 Epidemiology

How to do a pro search in Pubmed?

This special #TheAmylaseSchool infographics (or mini-course) is a guide to navigate the deep waters of Pubmed (and not get drown). I provide a pdf at the end of the Twitter Thread

1/5
Author Journal Date Title Abstract Language Affiliation
👇 How to search in Pubmed 2/5
Mesh terms, Boolean operators, My NCBI filters
👇

What is a Groove Pancreatitis (GP)? #GroovePancreatitis #ParaduodenalPancreatitis #CysticDystrophyDuodenalWall What are the symptoms, consequences, management?
Do not miss this @aegastro #HiloAEG #UEGambassador @my_ueg Twitter thread #TheAmylaseSchool The groove area or pancreaticoduodenal groove involves the space between the duodenum, the head of the pancreas and the common bile duct karger.com/Article/FullTe…

Cross-sectional imaging often reveals unexpected pancreatic cystic lesions, it is a frequent clinical problem, Should we observe or remove it? What's the diagnosis? Is our patient in danger of malignancy?
Don’t miss this @aegastro @my_ueg #EducAEG #UEGambassador twitter thread Importance of Pancreatic Cystic Neoplasms (PCN):
Most are asymptomatic at diagnosis, frequency increases with age
Symptoms: acute pancreatitis (Wirsung obstructed by the cyst or mucus), pain, obstructive chronic pancreatitis, jaundice
> symptoms, >malignancy risk!

Let´s talk about #PancreasHistory! The discovery of Insulin, Banting, Best, McLeod & Collip, the first patient who received insulin for #Diabetes Mellitus #UEGambassador @my_ueg @ESEndrocrinology @YouppiePancreas @EurPancClub @ChahalPrabhleen @PerelmansPearls #gigang For ancient physicians the most important feature of diabetes was the increased urine output. Diabetes was a term for polyuria derived from the classical Greek word "diabainein" meaning to walk with the legs apart, later diabetes "a passer through" or a "siphon".

Pancreatic exocrine insufficiency: causes, consequences, diagnosis and treatment.

Don´t miss this @my_ueg #UEGambassador twitter thread

#PancreasHGUA @aegastro @AESPANC @EurPancClub @pancreatology @hpb_so @me4_so #SoMe4Surgery @GVAsanitat @GVAsalualicante @isabial_iis Pancreatic juice is composed by
- Acinar secretion, rich in enzymes
- Ductal secretion: A) Water that will help to flush the acinar secretion B) Bicarbonate that will neutralize gastric acid in the duodenum; some enzymes like lipase do not work in an acid environment