Jyoti Baharani Profile picture
Jun 27 10 tweets 5 min read
Offering #dialysis to patients with a new diagnosis of #malignancy is always an emotive and complex affair if they present with an #AKI or #renaldysfunction
Sometimes it’s pretty clear - like in the 30 something who presents with a cervical cancer , bilateral hydronephrosis and K of 7- one will usually explain to The patient what’s the issue and buy them time for intervention which buys time for an oncology consult and further mx
Sometimes it’s not -70 plus with metastatic lung cancer and #AKI will likely need dialysis but is that the right thing - often it’s easy saying make the shared decision with the patient - but shock and the acuteness of the situation doesn’t help and true #SDM is seldom easy
So what does one do in that circumstance?
With the advent of acute oncology newer chemotherapy not all malignancies are a lost cause - it’s important then to dialyse the patient if it’s the safest thing to do - this publication provides a clear framework thelancet.com/journals/lanhl…
This is a good read and a comprehensive review by the inimitable Norbert Lamiere on #AKI in critically Ill #cancer Patients

ncbi.nlm.nih.gov/pmc/articles/P…
This more recent publication mentions that a multidisciplinary approach is necessary with the goal of reducing the incidence of AKI in cancer patients and improving patient outcomes

academic.oup.com/ckj/article/15…
A paywalled paper but worth a search provides an overview of the epidemiology and most common causes of acute kidney injury in patients with cancer unrelated to oncological treatment

ackdjournal.org/article/S1548-…
Despite having done this for a long time no 2 patients with similar malignancies have the same outcomes and it’s always a conundrum deciding on the right thing to do at the time of presentation 🙁
it’s important therefore to be honest and transparent and make shared decisions when possible and review treatment goals often when dealing with such cases #malignancy #AKI
Fin/

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