1. A short #MPX 🧵
The U.S. #monkeypox case count is now 2,323. Cases have been reported from all but 7 states: Wyoming, Montana, North Dakota, Mississippi, Alaska, Vermont and Maine. cdc.gov/poxvirus/monke… Image
2. The latest #monkeypox report from @ECDC_EU & @WHO_Europe is out. 36 countries in the European region have reported 10,604 cases. As usual, there's lots of interesting data in this report. monkeypoxreport.ecdc.europa.eu
3. Some stats:
- 42% of #monkeypox cases are 31 - 40 yo.
- 99.5% are male.
- 38% are people living with HIV (of cases for whom HIV status is known, ~1/5th of all cases)
- 94.5% had a rash.
- 31 were health workers, but they aren't thought to have been infected at work.
4. More #monkeypox stats:
- 65% had systemic symptoms (fever, muscle pain, fatigue, etc)
- 256 cases were hospitalised, but only 114 cases required clinical care. (I assume the rest were hospitalized for isolation purposes.)
- One case was admitted to ICU.
- Zero deaths.
5. Of the #monkeypox cases for whom gender is known, 48 are women.
The @ECDC_EU & @WHO_Europe weekly #MPX epi update is here: monkeypoxreport.ecdc.europa.eu Image

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More from @HelenBranswell

Jul 19
1. #ACIP, @CDCgov's vaccine advisory panel, meets today to study the data on Novavax's Covid vaccine and will vote on whether to recommend its use.
I'll be live tweeting the meeting.
If you want to watch the meeting yourself, it's viewable here: video.ibm.com/channel/VWBXKB…
2. Several members of #ACIP appear not to be attending today's meeting. Perhaps they'll join later but I think there are at least 4 of the 15 voting members not present.
3. Make that 3 missing members. I think.
#ACIP
Read 37 tweets
Jul 14
1. Short #MPX 🧵
There's an interesting #monkeypox paper today in @Eurosurveillanc from researchers in Barcelona. They took 147 specimens from 12 MPX patients, sampling saliva, semen and feces as well as skin/lesion samples and swabs of the throat and anus.
2. They found a high level of positivity among those samples — including finding #MPX DNA in the saliva of all 12 patients in their study. They also found #monkeypox virus DNA in semen (7/9 cases), urine (9/12 cases) and feces (8/12 cases). This raises an obvious question.
3. Sadly, this paper can't answer that question, which is: Can #MPX be transmitted through contact with bodily fluids/products? It can't answer it because the researchers didn't try to grow virus from the specimens, so it's not clear if this was viral debris or infectious virus.
Read 8 tweets
Jul 13
1. A thread on #PediatricHepatitis of unknown etiology.
@WHO issued an update today. It reports that 35 countries have reported 1010 cases. There've been 22 deaths (2%) & 46 (5%) of the children have needed liver transplants.
2. @WHO says it appears that the trend of cases is decreasing, but notes this should be interpreted with caution because there are reporting delays, likely under-reporting, and limited surveillance for such cases in many countries.
3. To that end, @WHO has launched an effort to try to assess whether there is a true increase in #PediatricHepatitis cases in the past 10 months or so. This comes on the heels of data from @CDCgov showing there has not been an increase of liver transplants among kids in the US.
Read 7 tweets
Jul 7
1. Short #MPXV thread, based on data from @WHO_Europe & @ECDC:
The Euro #monkeypox outbreak continues to grow. Of +5200 cases reported here, 29 were women — which seems to be an increase. 15 health workers among cases; not clear if exposure was on the job.
monkeypoxreport.ecdc.europa.eu
2. This may not be new-new, but I haven't noticed this previously: @WHO has pushed back the date on its case definition for suspected #monkeypox cases. They'd previously said March 15; now saying since Jan. 1. Suggests they believe the outbreak started earlier.
3. These regular #monkeypox updates from @WHO_Europe & @ECDC_EU contain really useful information, like this breakdown of symptomology among cases.
Read 9 tweets
Jul 1
1. A #MPXV 🧵
The director of @WHO_Europe issued a stark warning today about the state of the #monkeypox outbreak. Case counts have tripled in Europe in the past 2 weeks, @hans_kluge said.
who.int/europe/news/it…
2. @hans_kluge also noted while the majority of cases are still men who have sex with men, infections are being reported outside of that demographic. There is no reason #monkeypox will restrict itself to spread within a single group. Given the opportunity to transmit, it will.
3. @hans_kluge appeared to predict the #monkeypox outbreak will be declared a public health emergency of international concern sometime soon. An expert committee met last week & advised against declaring a #PHEIC for now.
Read 9 tweets
Jun 23
1. #ACIP is talking #monkeypox right now. Gonna try to live tweet.
This is the prior history in the US with #MPXV.
2. "Everything changed in May of 2022," @CDCgov's Agam Rao tells #ACIP.
3. The US #monkeypox case total is up to 176, @CDCgov says. There is some local transmission occurring, Rao said.
Read 18 tweets

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