Casey Kim Profile picture
Jul 26 4 tweets 3 min read
1/4: 🚨 “Do you think it’s ok to give this patient zofran? What about their QTc?” 🚨

#Tweetorial on QT prolonging drugs and torsades de pointes (TdP) 🧵
#MedEd #MedTwitter
2/4: How much does 8mg of ondansetron ⬆️ Qtc by?

What about 32 mg?

One study suggests low doses of QTc prolonging meds are unlikely to cause TdP in your avg patient, but would be careful if QTc > 500 or patient/drug is higher risk.
3/4: Not all drugs are created equal!

Common antiarrhythmics are more likely to cause TdP. Other drugs have a risk, but most are only documented as case reports (PMID: 32929996)
4/4: Here’s my summary on QT prolonging medications categorized by risk for Torsades de Pointes

Link to how risk categories were determined: wolterskluwer.com/en/expert-insi…

AZCERT runs @CredibleMeds (free online database with list of QT prolonging meds)

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