So they examined all the placentas of people known to have COVID-19 exposure during pregnancy and placentitis was found in people not fully vaccinated against COVID-19.

Study period pre-vaccination and early delta approx.
Mild maternal disease was associated with severe outcomes. 15/21 patients with stillbirth and COVID-19 placentitis had mild or asymptomatic disease initial COVID-19 infection.
January 1, 2020, through November 4, 2021 was the study period, and CDC published guidance that vaccines were recommended and safe on 11th August 2021.

That means that any women that were vaccinated and protected from placentitis would have been recently vaccinated.
So I am happy that placentitis is prevented by vaccines, but we need more information about how long this protection may last for in the context of waning and variants.

cdc.gov/media/releases…
There are more interesting facts in the article about strains and other outcomes.
The dichotomy between COVID-19 initial illness and placenta damage seems to be marked. COVID-19 appears to target placenta heavily.

This is a pathogen that warrants caution and control.

#VaccinesPlus
People that have COVID-19 exposure during pregnancy need close monitoring. I would advocate access to PCR testing too.

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More from @NjbBari3

Jul 30
A really nice study looking at the type of exposure and the type of symptoms.

Invasive = bite/scratch from prairie dog.

Non-invasive= other exposure to infected prairie dogs.

Note 80% upper respiratory tract symptoms.

#MonkeypoxIsAirborneToo

academic.oup.com/jid/article/19… Image
People that were infected without being bitten or scratched by the infected prairie dogs showed predominantly systemic 53.3% or upper respiratory 26.7% symptoms at presentation.

In my view, this could be because virus was inhaled rather than transferred across skin. Image
Those that did have an obvious skin breech (bite/scratch), developed rash earlier. Some even commenced at the sit of the wound.

Those that didn’t, had constitutional symptoms earlier, rash later, without the early localising lesion to the skin to indicate how virus got in. Image
Read 5 tweets
Jul 29
“…the majority of people in the community did not want to be told what to do…”

Yup. I don’t like to be told what to do either, but sometimes, it’s necessary…

#MaskMandates
Some examples when risks require regulations, laws or mandates to manage effectively.

Serious but uncommon risks.
Unintuitive or hidden risks.
Risk to others, not self.
Risks that occur a long time after an action is taken.
Risk is new or has changed.
Risk may be taken for financial or other gain, setting up traps for others.

etc.

We’ve always needed some limitations on the risks we take, otherwise bridges would fall down, people would still be windscreen pizza after an accident cos no seatbelt…
Read 4 tweets
Jul 29
What is this about believing in democracy, not technocracy?

Technocrats are supposed to inform democracy. Inform *people* so that they make choices that benefit them.

Why would these things necessarily be at loggerheads?
I’ve said it from the beginning. Having knowledge and the resources to put that knowledge into practice is very empowering.

Rampant COVID-19 is bad for business, bad for health, and a disoriented population that still doesn’t have the means to protect itself is vulnerable.
A good technocrat would give advice that strengthens the people, safeguard health, and this will inevitably improve confidence (based on reality), raise productivity, enhance resilience to future pandemics and strains of COVID-19.
Read 4 tweets
Jul 28
I graduated from UCL. It has changed a lot since I was there.

The ability to prioritise actions in an emergency is my job. You have to do things in the right order, or none of it works.

We need COVID control, so we can free up resources to do other work.
I don’t just mean health resources either. Everything is slower and deplete of workers due to sick leave, long term illness, carer duties, deaths, and some jobs have become frankly undesirable.
The expected benefits of ventilation and masks in essential services would be to reduce Reff and save lives.

How much… you have to do it to find out, because it hasn’t been done before.

We have to build this plane while flying. No room for excess baggage.
Read 4 tweets
Jul 28
Babies shouldn’t have to fight past this before they are even born.

Placenta.

Brown =vascular= good.
White stuff =useless.

#CutDownTransmission

the-scientist.com/news-opinion/d…
I’m going to take an educated guess and say that vaccination likely would prevent huge damage like this, but I think we are all familiar with the idea that it may vary depending on last dose and variant.

We can’t be living with this virus on the loose. It’s irresponsible!
Read 4 tweets
Jul 28
@healthgovau

SARS-CoV-2 does not have the required safety profile to administer it as a population level intervention to attempt to achieve “hybrid immunity”.
SARS-CoV-2 has serious adverse effects including neuro-inflammation and heart failure in the target population.

It is too transmissible. It circulates at high prevalence, persistently, and it readily transmits into vulnerable groups and we remain unable to prevent this.
It does not provide the intended outcome either. There is no evidence thus far of meaningfully durable immunity.

You can’t build the immunity wall. It is a folly.
Read 4 tweets

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