Kai Kupferschmidt Profile picture
Aug 17 20 tweets 17 min read
"More than 35,000 cases of monkeypox have now been reported to WHO, from 92 countries and territories, with 12 deaths", says @DrTedros at @WHO presser
"Almost 7,500 cases were reported last week, a 20% increase over the previous week, which was also 20% more than the week before"
@DrTedros @WHO Almost all cases being reported from Europe and Americas and among men who have sex with men, says @drtedros.
This underscores "the importance for all countries to design and deliver services and info tailored to these communities that protect health, human rights and dignity"
@DrTedros @WHO "The primary focus for all countries must be to ensure they are ready for monkeypox and stop transmission using effective tools", says @drtedros.
Mentions disease surveillance, contact tracing, tailored risk comms and community engagement as well as risk reduction measures.
@DrTedros @WHO "Vaccines may also play an important part in controlling the monkeypox outbreak", says @drtedros.
"However, for the moment, supplies of vaccines, and data about their effectiveness, are limited, although we are starting to receive data from some countries."
@DrTedros @WHO .@WHO is in contact with vaccine manufacturers and countries willing to share doses, says @drtedros.
"We remain concerned that the inequitable access to vaccines we saw during the covid19 pandemic will be repeated, and that the poorest will continue to be left behind."
@DrTedros @WHO Millions of people in Djibouti, Ethiopia, Kenya, Somalia, South Sudan, Sudan, and Uganda are facing starvation, says @DrTedros.
"Drought, conflict, climate change, and increasing prices for food, fuel and fertilizer are all contributing to lack of access to sufficient food."
@DrTedros @WHO "Hunger and malnutrition pose a direct threat to health, but they also weaken the body’s defenses, and open the door to diseases including pneumonia, measles and cholera", says @drtedros. "Food insecurity also forces some people to choose between paying for food and health care."
@DrTedros @WHO "While other partners are working to address the food crisis, WHO is addressing the resulting health crisis", says @drtedros.
"The $123.7 million we are appealing for will be used to prevent and control outbreaks, to treat malnutrition and to provide essential health services..."
@DrTedros @WHO "In the Ethiopian region of Tigray, the drought is compounding a man-made catastrophe for 6 million people who have been under siege from Ethiopian and Eritrean forces for 21 months, sealed off from the outside world", says @drtedros.
@DrTedros @WHO "As a result, the people of Tigray are facing multiple outbreaks of malaria, anthrax, cholera, diarrhea and more", says @drtedros.
"This unimaginable cruelty must end."
@DrTedros @WHO "Just in the past week, 15,000 people around the world lost their lives to #covid19", says @DrTedros. "15,000 deaths in a week is completely unacceptable when we have all the tools to prevent infections and save lives."
@DrTedros @WHO "The number of sequences shared per week has fallen by 90% since the beginning of this year, and the number of countries sharing sequences has dropped by 75%, making it so much harder to understand how the virus might be changing", says @DrTedros.
@DrTedros @WHO "With colder weather approaching in the northern hemisphere and people spending more time indoors, the risks for more intense transmission and hospitalization will only increase in the coming months", says @drtedros.
@DrTedros @WHO "There is a lot of talk about learning to live with this virus", says @drtedros.
"But we cannot live with 15,000 deaths a week. We cannot live with mounting hospitalizations and deaths. We cannot live with inequitable access to vaccines and other tools."
@DrTedros @WHO "Learning to live with #COVID19 does not mean we pretend it's not there", says @drtedros.
"It means we use the tools we have to protect ourselves and protect others."
@DrTedros @WHO On monkeypox:
"We have known from the beginning that this vaccine would not be a silver bullet, that it would not meet all the expectations that are being put on it and that we don't have firm efficacy data or effectiveness data in this context", says @PeopleDocGeneva.
@DrTedros @WHO @PeopleDocGeneva "The fact that we're beginning to see some breakthrough cases is really important information, because it tells us that the vaccine is not 100% effective", says @PeopleDocGeneva.
"We cannot expect 100% effectiveness at the moment based on this emerging information."
@DrTedros @WHO @PeopleDocGeneva On monkeypox:
"A number of countries are showing concerning trends and Brazil is one of them", says @PeopleDocGeneva
@DrTedros @WHO @PeopleDocGeneva "It's really important for all public health interventions that are available in the country to be put in place and for individuals to be given the information they need to protect themselves", says @PeopleDocGeneva on #monkeypox in Brazil.
@DrTedros @WHO @PeopleDocGeneva .@DrMikeRyan says he is surprised that all questions have been on monkeypox.
"It shows how much interest there is in monkeypox. But it also shows quite frankly, how interest is declining in COVID and how we don't seem to give a damn about what's happening in the Horn of Africa."

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More from @kakape

Aug 10
We are lucky that there is a vaccine that is licensed for monkeypox in many places. But even in countries that have doses and are using them, we don’t know how well it protects. Now researchers are trying to find out.
Story here and thread to come:

science.org/content/articl…
I’ve always found the challenge of answering a question like “How much does this vaccine protect?” fascinating.
It can seem technical, but I think it’s really important (particularly in the current situation) to explain how scientists go about this and the difficulties they face
Remember first of all that this is a vaccine developed to protect against smallpox. A study from 1988 showed that a smallpox vaccine offers something like 86% protection.
This is the paper: ncbi.nlm.nih.gov/pmc/articles/P…
And the crucial table:
Read 26 tweets
Aug 9
„We are who we are, in this moment, in this context, mediated in these ways. It is an abdication of responsibility for technologists to pretend that the technologies they make have no say in who we become“
A lot to like and think about here from @ezraklein
nytimes.com/2022/08/07/opi…
I find the question fascinating, to what extent certain societal changes are inherent to a technology and to what extent they are about how we as a society use these technologies. It reminded me of what Ted Chiang told @ezraklein a while back:
„Most of our fears or anxieties about technology are best understood as fears or anxiety about how capitalism will use technology against us. And technology and capitalism have been so closely intertwined that it’s hard to distinguish the two.“
Read 4 tweets
Aug 8
Important #monkeypox paper was just published in @TheLancet, so a quick thread…

Full paper is here: thelancet.com/action/showPdf…
@TheLancet The study, run by @oriolmitja and others, enrolled 181 consecutive patients at three hospitals in Madrid and Barcelona.
As usual, over 90% were men who have sex with men. You can see a breakdown of the participants here:
@TheLancet @oriolmitja More than a third of patients required medical treatment:

"Complications that required medical treatment were described in 70 (39%) participants, most frequently pain relief for proctitis, tonsillitis, and in participants with anal lesions."
Read 12 tweets
Jul 28
Had a chance to talk to @abcnews about monkeypox today.
Still find it incredibly difficult in these short TV interviews to get the big picture across while being nuanced and not saying “you know” a gazillion times. But this was almost 6 minutes and I really appreciated that!
“It is a difficult situation because we need to always be very clear: What is the situation right now? Why are we concentrating on one particular group? And at the same time make it very clear that the situation can change.”
“The likelihood of viruses jumping into humans and then spreading fast is becoming higher, so we’re in this moment where we need to be better at dealing with it and sadly we seem to be worse…”
And quoting @arimoin: “It’s easier to stay out of trouble than get out of trouble”
Read 4 tweets
Jul 27
"More than 18.000 cases of monkeypox have now been reported to WHO from 78 countries, with more than 70% of cases reported from the European region and 25% from the region of the Americas", says @drtedros at @WHO presser.
@DrTedros @WHO "So far, five deaths have been reported, and about 10% of monkeypox cases are admitted to hospital to manage the pain caused by the disease", says @drtedros.
@DrTedros @WHO "This is an outbreak that can be stopped if countries, communities and individuals inform themselves, take the risk seriously, and take the steps needed to stop transmission and protect vulnerable groups", says @DrTedros."The best way to do that is to reduce the risk of exposure"
Read 9 tweets
Jul 26
We are two months into an outbreak of monkeypox across the world and I find it incredibly frustrating that we seem to be stuck on debating whether this virus is really overwhelmingly affecting MSM (and whether it is homophobic to point that out) or whether to call this an STD.
Where we have data, it shows very clearly that the virus is affecting mostly gay men and our sexual networks. This is not because of biased testing either. Just look at the percentage of positive tests in @UKHSA's latest briefing:
Adult men: 54% positive
Adult women: 2 % positive
@UKHSA Obviously everybody *can* get this virus and it *can* spread through other ways than close skin-to-skin contact during sexual encounters.
But right now we are seeing it mostly spread in MSM and through sexual encounters.
Read 11 tweets

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