Thread by @adfurlan

11 super interesting facts about the PAIN NEURO MATRIX that everyone should know:
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#1 ... is a matrix of brain structures🧠that process and regulate pain information

#2 ... includes various nuclei in the brainstem, the amygdala, hypothalamus, thalamus and areas of the cerebral cortex

#3 ... Men and women have similar pain matrix, but women maintain activation longer than men after stimulation of the PAIN matrix

#4 ... creates pain even in the absence of nociception

#5 ... is linked to feelings, behaviours and thoughts. It means that the meaning the person assigns to the pain can make the pain worse or better, longer or shorter duration

#6 ... it generates a top-down response that inhibits the bottom-up pain signals

#7 ... psychological and genetic risk factors are related to the pain matrix

#8 ... it determines how intense the pain will be felt by the person

#9 ... fibromyalgia is an example of deregulation of the pain matrix

#10 ... fear of pain makes the pain worse because it activates the pro-nociception areas of the pain matrix

#11 ... brain retraining is capable of controlling the pain matrix and changing it

Which fact was most interesting to you?

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#pain #neuroscience #chronicpain #Fibromyalgia #MedTwitter