"Are we better prepared?" asks @EckerleIsabella as she closes #SSM@SwissMicrobe with her keynote on challenges in prevention & preparedness for emerging viruses. #SARSCoV2 & #monkeypox have highlighted these issues; what do we know & where do we stand?
1/N
Perhaps particularly of note are viruses that aren't entirely new, but keep popping up, or appear in new hosts, new places, or with new symptoms a while after identification. How & how often does this happen?
Others we know well & have fought before, but appear again!
2/N
Understanding viral emergence is also not just for viral biologists: there are so many factors that provide influence, from that virus and host to environmental, anthropic, and human-animal interface.
3/N
In #SARSCoV2 we have moved from a phase of very unexpected variants to one with many Omicron "babies". What might dominate next -- will it be the same everywhere? We see a lot happening but exact prediction is difficult.
4/N
What about #influenza#flu ? We saw little circulation during COVID measures, but it's made a big reappearance. This alone is a lot of pressure on hospitals & a lot of illness. What can we expect in the North, what should try & prepare for?
5/N
And of course... Emerging viruses are part of larger and interconnected issues like #climatechange & biodiversity loss - along with changing use of land - and misinformation, fragmentation of our societies, & loss of trust.
6/N
"We are jumping from virus to virus but never take time to invest in understanding & surveillance to fully understand them."
Surveillance often falls in a gap: research sees it as public health, public health sees it as research - nobody funds it though we would all benefit!
7/N
And a great quote to finish.
"Any new disease that is emerging faster than our understanding is never under control."
I would argue it can also be applied to "old" viruses that may reappear and/or change faster than we can keep up!!
I'm excited to announce a new paper with @MLReichmuth and @C_Althaus, out now in @PLOSPathogens!
We used phylogenetics & modelling to investigate the introduction & expansion of #SARSCoV2 Alpha & Delta variants into #Switzerland & to simulate different interventions.
1/17
First, we wanted to estimate the number of times Alpha & Delta were introduced into Switzerland before they were dominant.
For this we used sequences: we looked for where Swiss Alpha/Delta seqs descend from non-Swiss sequences - coming to Switzerland from elsewhere.
2/17
We looked at two ways of counting these introductions:
Liberal: every Swiss sequence coming from non-Swiss sequences is an introduction
Conservative: only the first Swiss sequence in a subtree of mixed-Swiss-non-Swiss sequences is an introduction
Benevolent dictators have no place in academic science.
I don't care if they usually make the right decision. Or if people don't think they've abused their power yet.
Science should not depend on one person being well-behaved.
Balance should be built in, power distributed.
1/5
"If you want to go fast, go alone, if you want to go far, go together" the African proverb says.
Can driven, visionary people start up groundbreaking ideas & cut through barriers to implement them? Absolutely! This 100% is part of science.
2/5
But if you want your idea to be a keystone of science communities & the public, you have to make it about more than *you*.
If you want to run a private business, go do that.
If you want to be keystone of public science, you have to be transparent, trustworthy, & stable.
3/5
23B (XBB.1.16) is now available on CoVariants! It's visible as part of Per Country & Per Variant plots, on the shared mutation page - and of course, has a page of its own.
As I covered earlier, 23B (XBB.1.16) is descended from the recombinant 22F (XBB) variant, with some additional mutations. You can read more about how it evolved & acquired those mutations below 👇🏻.
Also from this article:
'Marion Koopmans ... says she has received multiple calls from Bogner“with a rather intimidating tone.” So have colleagues, she adds. “I have heard similar experiences from quite a few.”'
And:
"And Science heard many stories about researchers who saw their data curtailed, or cut off, without explanation. Some linked the actions to their being critical of GISAID or being seen as a potential threat."
If you're an early career researcher (yes even 'just' a PhD student!) 1 of my biggest pieces of advice would be:
Go claim/create your Google Scholar page!! 👈🏻✍️🏻
I put this off bc I thought I 'didn't have enough on it'. I also generally thought "nobody is looking for me".
1/4
Now that I'm (a little) on the other end, I see how wrong I was.
It's *just fine* to not have "much" in your Google Scholar profile - anyone worth their salt will be evaluating you relative to your career state.
Much more important: to be findable!
2/4
And alongside that: it's so useful to have an easy way for people to see what your field is & what you've been up to/who you work with/your expertise.
Google Scholar is also pretty easy to maintain (will vary depending on how unique your name is), as it auto-updates.
3/4