Joseph Allen Profile picture
Sep 6 25 tweets 5 min read
"Mysterious outbreak in Argentina solved"

Newly interested in #Legionella? Here's an excerpt from my book, #HealthyBuildings (in the opening chapter, after my FBI story...)

And...good time to mention...new edition comes out October 18. First look at the new cover!

1/n
It was during one of my first forensic investigations of a “sick building” that I first saw the power and potential of this burgeoning Healthy Buildings movement. This was no ordinary case of sick building syndrome...
It wasn’t a stuffy cubicle farm where people sometimes report symptoms like headaches, eye irritation, dizziness, or allergic reactions. I don’t mean to diminish those types of sick buildings in any way, but this was a hospital and the lives of four people were in jeopardy.
It was Grady Hospital in Atlanta in 2009. Four patients on the same two floors had developed Legionnaires’ disease within the same month: a classic disease outbreak scenario.
Before we go any further with how the Grady Hospital outbreak unfolded, let me give you some quick background on Legionnaires’ disease, a disease that to this day continues to impact many thousands of Americans every year, in and around buildings.
Legionnaires’ disease is pretty common—7,500 cases are reported each year, but this is a gross underestimate of the actual number of cases. Legionnaires’ disease is underdiagnosed and underreported. It’s also a deadly disease—1 in 10 people who get it die.
Legionnaires’ disease was first “discovered” after the infamous outbreak at the convention of the American Legion at the Bellevue-Stratford Hotel in 1976.
Over the course of a few days, 2,000 people became sick with a severe, life-threatening type of pneumonia. 29 of those people died. The scariest part? No one knew the cause. The other 10,000 people who attended the convention were, rightfully, in a panic about their own health.
This was front-page-of-Newsweek-type stuff. (In the age before the rise of internet news, making
the cover of Newsweek was a big deal.)
The disease was dubbed “Legionnaires’ disease” because of the location of this outbreak—at the American Legion meeting, where members call themselves Legionnaires.
After several months of investigation, the US CDC identified the cause of the outbreak: a bacterium in the building air-conditioning system that they named—you guessed it—Legionella.
Legionella are naturally occurring waterborne bacteria that can cause a pneumonia-like illness. Out in the natural world, where they are everywhere, their numbers stay small. But given an environment where water stagnates and where temperatures stay lukewarm, they proliferate.
That makes a few places in a building a nice home for Legionella.They like to live, and grow, inside the biofilm in water pipes, inside cooling towers on the roof of a building, or, in the case of the infamous American Legion outbreak, in the condensate drains of air conditioners
Within a building (a hospital, for example), Legionella are also commonly found in “dead legs” of a building’s plumbing system. Dead legs are sections of the plumbing system areas where an old line was cut off, say, during a renovation in which a water fountain was removed.
Sometimes, for reasons of efficiency, cost, laziness, or shortsightedness, rather than cutting the water line all the way back to its joint in the plumbing system, the building owner just caps the pipe where the fountain used to be and patches up the wall.
Thus, a dead leg is created.

The dead leg of the system is that extension of pipe that is no longer part of the normal circulating water flow, so the water stagnates and stays luke-warm. These are the perfect conditions for Legionella to grow.
And importantly, they grow in an area where they can’t be easily “attacked” by residual disinfectant in the building’s water supply (traditionally chlorine), and therefore they act as a source that continually feeds bacteria into the main line of the water system.
But simply having Legionella in water doesn’t mean you’ll get sick from it. The way we can get Legionnaires’ disease is by breathing in the bacteria.
So the mere presence of Legionella in a building doesn’t mean there’s a problem; the bacteria must also be aerosolized, or released into the air in tiny droplets.
In the case of the American Legion outbreak, the bacteria were aerosolized and distributed around the convention through the air-conditioning system.
Since that time, we have done a much better job of controlling Legionella in our cooling systems.

(For the most part, anyway...
Outbreaks still frequently occur, like the outbreak in Disneyland in 2017 that impacted 22 people, or the outbreak in Portugal in 2014 that sickened 336 and killed 10.)
And in most commercial buildings, there really aren’t many opportunities indoors to aerosolize the water in any meaningful way, other than through spray from the sink or postflush spray from the
toilet. (Yes, you read that right.)
Hospitals, on the other hand, have a lot of opportunities for aerosolizing water that other types of buildings don’t always have—showers. (Hotels fall into this category, too, and there have been many high-profile outbreaks in hotels.)
Now that you’re armed with the basics of Legionella, let’s go back to Grady Hospital in Atlanta."

[Want to know what happened next?? #HealthyBuildings👇]

amazon.com/dp/0674278364/…

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More from @j_g_allen

Sep 1
All the strategies people are focusing on now, we knew them 2 years ago:

“Joseph Allen, the directir of the Healthy Buildings program at Harvard’s SPH, wrote a 62-page plan with a dozen colleagues listing steps that schools could take to reduce transmission risk.

1/n
“To improve ventilation and air quality, schools with AC could upgrade their air filters, while schools without it could make sure that their windows opened and set up fans to circulate fresh air from outdoors; when it got too cold, they could install portable air purifiers.”
And so much of the schools conversation that summer failed to even acknowledge the risks of kids out of school:

“There’s certainly no such thing as zero risk in anything we do, and that is certainly the case during a pandemic,” he said in a conference call to present the plan.
Read 4 tweets
Sep 1
The harms to kids from being out of school, on the other hand, are severe. They are accumulating. And they could last for decades.

nytimes.com/2021/12/20/opi…
A report by McKinsey examining Covid-19 effects on the 2020-21 school year found that the pandemic left students five months behind on math and four months behind in reading.
Schools with majority Black and brown populations saw deeper losses: six months behind in math and five to six months behind in reading.
Read 5 tweets
Sep 1
“…the worst drop in math and reading scores in decades…”

1/2 wsj.com/articles/educa…
June 2020

“First, school closures are creating “virtual dropouts.”…This will increase our country’s education gap and exacerbate racial and social inequalities — with impacts that will persist for years.”

washingtonpost.com/opinions/2020/…
Read 5 tweets
Aug 25
Excellent article by @zeynep on long covid:

"The scale of the pandemic has made the importance of postviral ailments harder to deny and the need for research greater, but we have not yet risen to the task."

THREAD pulls out issues hindering response
nytimes.com/2022/08/25/opi…
--> "Under the C.D.C. definition, someone with a single symptom just four weeks after illness can be lumped under the long Covid umbrella with someone bedbound for years."
--> "The symptom descriptions for long Covid are too vague. Do “brain fog” and “fatigue” mean people don’t feel as sharp as they were and are a little off their jogging times, or are they experiencing a cognitive crisis so profound that they cannot find words..."
Read 9 tweets
Aug 19
CLIMATE CHANGE
#InflationReductionAct

It is *really* important to understand this new #FalconCurve paper.

A short thread with 3 key takeaways
1. Seasonally, building energy demands vary by a factor of 1.6x. Most current plans for decarbonizing buildings do not take this seasonal variation into account.
2. If all buildings convert to electricity, electricity demand will switch from peaking in the summer to peaking in the winter. To handle this demand will require a massive buildout of renewable energy and seasonal energy storage.
#ElectrifyEverything
Read 7 tweets
Aug 3
In addition to the very cool name (#FalconCurve), you’re *really* going to want to know what’s in our paper if you’re at all interested in:

#ClimateChange
#GreenBuildings
#ElectrifyEverything
#EnergyEfficiency
#Sustainability
#HealthyBuildings

THREAD
bu.edu/sph/news/artic…
Direct fossil fuel consumption by buildings, burned in water heaters, furnaces, and other heating sources, account for nearly 10 percent of greenhouse gas emissions in the United States.
Switching to an electric system that powers heating through renewable energy sources, rather than coal, oil, and natural gas—the process known as building electrification or building decarbonization—is a crucial step towards achieving global net-zero climate goals.
Read 11 tweets

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