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Oct 19, 2022 6 tweets 6 min read Read on X
1/🚨New Episode🚨
Aspirin for Primary Prevention: #MindtheGap Segment

What do current ACC and USPSTF guidelines say about daily low-dose #aspirin for the primary prevention of #cardiovascular disease?

🎧: apple.co/3VPRCV4
Sponsor: bit.ly/TCChoZ Image
2/Throwback to medical school pathophysiology!

Remember how the #atherosclerotic process takes place in blood vessels? 🫀

Now, where does #aspirin exert its effect during this cascade? 🤔 Image
3/What do the most recent #RCTs inform us about the use of aspirin for primary prevention ⁉️

ASCEND, ARRIVE, ASPREE!

#CoreIMJournalClub 📕 Image
4/How should we use the #ASCVD 10-year risk calculator? 🧮

Are there any other important risk factors that we are not accounting for? 😮

Ultimately, how can we best tailor the decision of #aspirin for primary prevention for each and every patient? 👩‍🚒👩‍🎨👩‍⚖️ Image
5/Incredibly grateful for the #dreamteam behind this relaunch of #MindtheGap!

Host @gregorykatz @eucaryotic
Producers @ShreyaTrivediMD @YichiZzzzz
Peer Review: Kinjan Parikh
Graphics: @elizzieh08

We hope you enjoyed our discussion of #aspirin, stay tuned for more learning!
6/ Make sure to check out our Shownotes & link for ACP CME credit!

🗒️: bit.ly/3gk4O40
CME: bit.ly/CIMCME

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More from @COREIMpodcast

Jun 5
1/ 🚨 NEW #5Pearls on HFpEF!

HFpEF is:
- Clinical syndrome of heart failure w/ EF 50%+
- ☂️ term | Heterogeneous disease 

HFpEF is NOT:
- Classic high BP, causing stiff ventricles

🖥️ :
ACP CME:
Sponsor:  coreimpodcast.com/2024/06/05/hfp…
bit.ly/CIMCME
coreimpodcast.com/Freed
Image
2/ Clinically, HFpEF is:

🫀Dyspnea on exertion
🫀PND
🫀Orthopnea
🫀Fatigue
🫀Exercise intolerance
🫀JVD
🫀Pulmonary rales
🫀LE edema
3/ On echo, HFpEF is NOT:
🫀Just diastolic dysfunction

**Diastolic dysfunction CAN be seen in HFpEF 

But, it was not observed on resting echocardiograms of ⅓ of HFpEF patients in the Paragon-HF trial ‼️
Read 7 tweets
May 13
1/ 🚨 NEW #5Pearls episode on Cardiorenal Considerations 🫀🫘

So many diuretic options, so which to choose and why?

Use the toolkit ⤵️ for all your diuresis needs!

🖥️:
CME: 
Sponsor:  bit.ly/3wx8tnB
bit.ly/CIMCME
coreimpodcast.com/Freed
Image
2/ Not all AKI in heart failure is cardiorenal syndrome!

In pure cardiorenal, expect a “bland” UA with no:
🥩 Protein
🩸 Blood
🦠 Granular or other cell casts!

**Remember, keep a broad differential for AKI
3/ You suspect volume overload in a patient…what dose of diuretic do you start with?

2.5x their home dose of diuretic (in IV form)!

IV options include:
💉 Furosemide
💉 Bumetanide

**Bumetanide drip at higher doses is associated with myalgias
Read 9 tweets
Jun 8, 2023
1/ Time for #12LeadThursday!

What’s the axis and do you notice anything about the precordial leads? Image
2/ What do you see on ECG to identify extreme axis deviation?

Negative deflection in lead I + negative deflection in aVF = extreme axis deviation Image
3/ What about the precordial leads?

Do you notice dominant R waves, S waves, or T-wave inversions? Image
Read 5 tweets
Apr 13, 2023
1/ What better way to end off a week of pacemakers and ICDs than recapping and revisiting our #12LeadThursday series!

🧵 Image
2/ Which patients get pacemakers?

Think of 2 big buckets: conduction disease and heart failure Image
3/ Let’s start with conduction disease!

Refresh your memory with this past byte - 80 y/o M with hx of CABG…what's the rhythm?
bit.ly/40cAry0
Read 15 tweets
Jan 18, 2023
1/ Atrial Fibrillation: #GrayMatters Series

What do you do with that episode of #Afib when sick or post-op in the hospital?

What type of monitoring is best?

🎧: link.chtbl.com/Afib
🗒️: bit.ly/3QPiLFt
CME: bit.ly/CIMCME
Sponsor: go.amboss.com/CoreIM-E9
2/ When do you start AC for new Afib post-op?

We hope this infographic will be handy for the many times we may be in the gray zone!

From @accpchest guidelines

A few things to consider:
🤔 Patient specific risk
🤔 Blood thinner of choice
🤔 Bleeding risk of the surgery
3/ Credit to the team that worked tirelessly on this!

Hosts: Dr. Nick Villano, @Ali_Trainor, @FreedoBaggins
Off-air producer: @ShreyaTrivediMD
Experts: @jasonmatosmd, @PoojaJagadishMD, @gregorykatz
Graphic: Josie Levey

🎧:link.chtbl.com/Afib

coreimpodcast.com/2023/01/18/dia…
Read 5 tweets
Dec 15, 2022
1/🚨New Episode🚨
The Lipid Panel Reimagined: #MindtheGap Segment

How do you interpret the #lipidpanel to help inform patients' risk for #cardiovascular disease? Do you use #ApoB? 🧐

🎧: link.chtbl.com/Lipids
Sponsor: go.amboss.com/CoreIM-E8
2/ Unfortunately, our patient is stuck in "bumper-to-bumper" #cholesterol traffic 🚗!

See traffic analogy to understand why ApoB can give us information that LDL-C may not:

#Mindblown! 🤯
3/ Overall, LOWER ⬇️ is better for both #LDL-C and #ApoB in terms of reducing #CV disease risk!

But #discordance between LDL-C vs. ApoB is actually quite common!

Take a look at the orange line to see how ApoB confers a higher CVD risk over time 👇
Read 5 tweets

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